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Structured interviews were administered to an ethnically diverse sample of 394 adolescents (114 girls, 280 boys; mean\u2009=\u200916.30 years; SD\u2009=\u20091.15 years; 44.9% Hispanic, 20.6% African American, 25.4% White non-Hispanic, and 9.1% other) in 2 outpatient treatment settings. <\/jats:p><jats:p> Results. Path analyses yielded findings consistent with a mediation model. Alcohol abuse and dependence symptoms mediated (1) relations between emotional neglect scores and sex with co-occurring alcohol use and (2) relations between sexual abuse scores and sex with co-occurring alcohol use. Drug abuse and dependence symptoms mediated relations between (1) neglect scores and (2) sexual intercourse with co-occurring alcohol or drug use, as well as unprotected sexual intercourse. <\/jats:p><jats:p> Conclusions. Efforts to treat alcohol or drug use problems among adolescents or to prevent transmission of HIV or other sexually transmitted infections among youths with substance use problems may require tailoring treatment or prevention protocols to address client histories of maltreatment. <\/jats:p>","DOI":"10.2105\/ajph.2011.300628","type":"journal-article","created":{"date-parts":[[2012,3,8]],"date-time":"2012-03-08T20:51:47Z","timestamp":1331239907000},"page":"S250-S257","source":"Crossref","is-referenced-by-count":59,"title":["Childhood Maltreatment Histories, Alcohol and Other Drug Use Symptoms, and Sexual Risk Behavior in a Treatment Sample of Adolescents"],"prefix":"10.2105","volume":"102","author":[{"given":"Assaf","family":"Oshri","sequence":"first","affiliation":[{"name":"Assaf Oshri is with the Department of Clinical and Social Sciences, Mt. Hope Family Center, University of Rochester, Rochester, NY. Jonathan G. 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