{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T10:14:35Z","timestamp":1792491275421,"version":"4.5.0"},"reference-count":48,"publisher":"American Public Health Association","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Public Health"],"published-print":{"date-parts":[[2014,3]]},"abstract":"<jats:p> Objectives. Because only a fraction of patients with acute viral hepatitis A, B, and C are reported through national surveillance to the Centers for Disease Control and Prevention, we estimated the true numbers. <\/jats:p><jats:p> Methods. We applied a simple probabilistic model to estimate the fraction of patients with acute hepatitis A, hepatitis B, and hepatitis C who would have been symptomatic, would have sought health care tests, and would have been reported to health officials in 2011. <\/jats:p><jats:p> Results. For hepatitis A, the frequencies of symptoms (85%), care seeking (88%), and reporting (69%) yielded an estimate of 2730 infections (2.0 infections per reported case). For hepatitis B, the frequencies of symptoms (39%), care seeking (88%), and reporting (45%) indicated 18\u2009730 infections (6.5 infections per reported case). For hepatitis C, the frequency of symptoms among injection drug users (13%) and those infected otherwise (48%), proportion seeking care (88%), and percentage reported (53%) indicated 17\u2009100 infections (12.3 infections per reported case). <\/jats:p><jats:p> Conclusions. These adjustment factors will allow state and local health authorities to estimate acute hepatitis infections locally and plan prevention activities accordingly. <\/jats:p>","DOI":"10.2105\/ajph.2013.301601","type":"journal-article","created":{"date-parts":[[2014,1,16]],"date-time":"2014-01-16T21:01:07Z","timestamp":1389906067000},"page":"482-487","source":"Crossref","is-referenced-by-count":79,"title":["Estimating Acute Viral Hepatitis Infections From Nationally Reported Cases"],"prefix":"10.2105","volume":"104","author":[{"given":"R. Monina","family":"Klevens","sequence":"first","affiliation":[{"name":"At the time of the study, all authors were with the Division of Viral Hepatitis, National Center for HIV\/AIDS, Viral Hepatitis, STDs and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen","family":"Liu","sequence":"additional","affiliation":[{"name":"At the time of the study, all authors were with the Division of Viral Hepatitis, National Center for HIV\/AIDS, Viral Hepatitis, STDs and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henry","family":"Roberts","sequence":"additional","affiliation":[{"name":"At the time of the study, all authors were with the Division of Viral Hepatitis, National Center for HIV\/AIDS, Viral Hepatitis, STDs and TB Prevention, Centers for Disease Control and Prevention, Atlanta, 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