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Most were school based, conducted in the United States, and effective for multiple forms of substance use. Effects were small, in line with findings for other universal prevention programs. In some studies, effects for more than 1 health risk behavior only emerged at long-term follow-up.<\/jats:p>\n                  <jats:p>Integrated prevention programs are feasible and effective and may be more efficient than discrete prevention strategies.<\/jats:p>","DOI":"10.2105\/ajph.2014.301874","type":"journal-article","created":{"date-parts":[[2014,3,13]],"date-time":"2014-03-13T16:06:48Z","timestamp":1394726808000},"page":"e19-e41","source":"Crossref","is-referenced-by-count":212,"title":["A Systematic Review of Effective Interventions for Reducing Multiple Health Risk Behaviors in Adolescence"],"prefix":"10.2105","volume":"104","author":[{"given":"Daniel R.","family":"Hale","sequence":"first","affiliation":[{"name":"The authors are with the General and Adolescent Paediatrics Unit, Institute of Child Health, University College London, 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