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We used existing administrative data to measure MSA-level socioeconomic status; criminal justice activities; expenditures on social welfare, health, and policing; and histories of Black uprisings (1960\u20131969) and urban renewal funding (1949\u20131974). We regressed Black IDU prevalence on these predictors by using hierarchical linear models.<\/jats:p><jats:p>Results. Black IDU prevalence was lower in MSAs with declining Black high-school dropout rates, a history of Black uprisings, higher percentages of Black residents, and, in MSAs where 1992 White income was high, higher 1992 Black income. Incarceration rates were unrelated.<\/jats:p><jats:p>Conclusions. Contextual factors shape patterns of drug use among Black individuals. Structural interventions, especially those that improve Black socioeconomic security and political strength, may help reduce IDU among Black adolescents and adults.<\/jats:p>","DOI":"10.2105\/ajph.2015.302911","type":"journal-article","created":{"date-parts":[[2015,12,21]],"date-time":"2015-12-21T21:40:58Z","timestamp":1450734058000},"page":"517-526","source":"Crossref","is-referenced-by-count":18,"title":["Contextual Predictors of Injection Drug Use Among Black Adolescents and Adults in US Metropolitan Areas, 1993\u20132007"],"prefix":"10.2105","volume":"106","author":[{"given":"Hannah L.\u2009F.","family":"Cooper","sequence":"first","affiliation":[{"name":"Hannah L.\u2009F. Cooper, Sabriya Linton, Josalin Hunter-Jones, Maria Zlotorzynska, and Mary E. Wolfe are with the Department of Behavioral Sciences and Health Education, Rollins School of Public Health, Emory University, Atlanta, GA. 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