{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T03:32:03Z","timestamp":1787023923154,"version":"build-2736575974"},"reference-count":40,"publisher":"American Public Health Association","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Public Health"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:p>Objectives. To investigate the long-term (12- and 24-month) impact of an economic empowerment intervention on HIV risk behaviors and mental health among school-going adolescent girls in Uganda.<\/jats:p>\n                  <jats:p>Methods. A total of 1260 girls aged 14 to 17 years were randomized at the school level to (1) standard health and sex education (controls; n\u2009=\u2009408 students; n\u2009=\u200916 schools), (2) 1-to-1 matched savings youth development account (YDA; n\u2009=\u2009471 students; n\u2009=\u200916 schools), or (3) combination intervention (YDA and multiple family group [YDA+MFG]; n\u2009=\u200915 schools; n\u2009=\u2009381 students). Mixed-effects models were fitted.<\/jats:p>\n                  <jats:p>Results. YDA and YDA+MFG girls had significantly lower depressive symptoms and better self-concept than controls at 24 months. Only YDA+MFG girls had significantly lower hopelessness levels than controls. There were no significant study group differences at 12 and 24 months for sexual risk-taking behavior and attitudes. There was no significant difference between YDA and YDA+MFG groups for all outcomes.<\/jats:p>\n                  <jats:p>Conclusions. Providing YDA and MFG can positively improve adolescent girls\u2019 mental health, but our analyses showed no significant differences across groups on sexual risk-taking behaviors. Future studies may consider replicating these interventions and analyses in older populations, including those transitioning into young adults.<\/jats:p>\n                  <jats:p>Trial Registration. ClinicalTrials.gov Identifier: NCT03307226. (Am J Public Health. 2023;113(3):306\u2013315. https:\/\/doi.org\/10.2105\/10.2105\/AJPH.2022.307169 )<\/jats:p>","DOI":"10.2105\/ajph.2022.307169","type":"journal-article","created":{"date-parts":[[2023,1,5]],"date-time":"2023-01-05T15:59:51Z","timestamp":1672934391000},"page":"306-315","source":"Crossref","is-referenced-by-count":24,"title":["Economic Empowerment, HIV Risk Behavior, and Mental Health Among School-Going Adolescent Girls in Uganda: Longitudinal Cluster-Randomized Controlled Trial, 2017\u20122022"],"prefix":"10.2105","volume":"113","author":[{"given":"Fred M.","family":"Ssewamala","sequence":"first","affiliation":[{"name":"Fred M. Ssewamala and Rachel Brathwaite are with the International Center for Child Health and Development, Brown School, Washington University in St Louis, MO. Torsten B. Neilands is with the Division of Prevention Science, University of California, San Francisco."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel","family":"Brathwaite","sequence":"additional","affiliation":[{"name":"Fred M. Ssewamala and Rachel Brathwaite are with the International Center for Child Health and Development, Brown School, Washington University in St Louis, MO. Torsten B. Neilands is with the Division of Prevention Science, University of California, San Francisco."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Torsten B.","family":"Neilands","sequence":"additional","affiliation":[{"name":"Fred M. Ssewamala and Rachel Brathwaite are with the International Center for Child Health and Development, Brown School, Washington University in St Louis, MO. Torsten B. 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