{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T17:29:54Z","timestamp":1790098194353,"version":"4.0.1"},"reference-count":32,"publisher":"American Public Health Association","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Public Health"],"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:p> Objectives. To test the hypothesis that law enforcement efforts to disrupt local drug markets by seizing opioids or stimulants are associated with increased spatiotemporal clustering of overdose events in the surrounding geographic area. <\/jats:p><jats:p> Methods. We performed a retrospective (January 1, 2020 to December 31, 2021), population-based cohort study using administrative data from Marion County, Indiana. We compared frequency and characteristics of drug (i.e., opioids and stimulants) seizures with changes in fatal overdose, emergency medical services nonfatal overdose calls for service, and naloxone administration in the geographic area and time following the seizures. <\/jats:p><jats:p> Results. Within 7, 14, and 21 days, opioid-related law enforcement drug seizures were significantly associated with increased spatiotemporal clustering of overdoses within radii of 100, 250, and 500 meters. For example, the observed number of fatal overdoses was two-fold higher than expected under the null distribution within 7 days and 500 meters following opioid-related seizures. To a lesser extent, stimulant-related drug seizures were associated with increased spatiotemporal clustering overdose. <\/jats:p><jats:p> Conclusions. Supply-side enforcement interventions and drug policies should be further explored to determine whether they exacerbate an ongoing overdose epidemic and negatively affect the nation\u2019s life expectancy. (Am J Public Health. 2023;113(7):750\u2013758. https:\/\/doi.org\/10.2105\/AJPH.2023.307291 ) <\/jats:p>","DOI":"10.2105\/ajph.2023.307291","type":"journal-article","created":{"date-parts":[[2023,9,6]],"date-time":"2023-09-06T21:36:11Z","timestamp":1694036171000},"page":"750-758","source":"Crossref","is-referenced-by-count":89,"title":["Spatiotemporal Analysis Exploring the Effect of Law Enforcement Drug Market Disruptions on Overdose, Indianapolis, Indiana, 2020\u20132021"],"prefix":"10.2105","volume":"113","author":[{"given":"Bradley","family":"Ray","sequence":"first","affiliation":[{"name":"Bradley Ray is with RTI International, Research Triangle Park, NC. Steven J. Korzeniewski is with the School of Medicine, Wayne State University, Detroit, MI. George Mohler is with the Computer Science Department, Boston College, Chestnut Hill, MA. Jennifer J. Carroll is with the Department of Sociology and Anthropology, North Carolina State University, Raleigh. Brandon del Pozo is with the Warren Alpert School of Medicine, Brown University, Providence, RI. Grant Victor is with the School of Social Work,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven J.","family":"Korzeniewski","sequence":"additional","affiliation":[{"name":"Bradley Ray is with RTI International, Research Triangle Park, NC. Steven J. Korzeniewski is with the School of Medicine, Wayne State University, Detroit, MI. George Mohler is with the Computer Science Department, Boston College, Chestnut Hill, MA. Jennifer J. Carroll is with the Department of Sociology and Anthropology, North Carolina State University, Raleigh. Brandon del Pozo is with the Warren Alpert School of Medicine, Brown University, Providence, RI. Grant Victor is with the School of Social Work,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George","family":"Mohler","sequence":"additional","affiliation":[{"name":"Bradley Ray is with RTI International, Research Triangle Park, NC. Steven J. Korzeniewski is with the School of Medicine, Wayne State University, Detroit, MI. George Mohler is with the Computer Science Department, Boston College, Chestnut Hill, MA. Jennifer J. Carroll is with the Department of Sociology and Anthropology, North Carolina State University, Raleigh. Brandon del Pozo is with the Warren Alpert School of Medicine, Brown University, Providence, RI. Grant Victor is with the School of Social Work,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer J.","family":"Carroll","sequence":"additional","affiliation":[{"name":"Bradley Ray is with RTI International, Research Triangle Park, NC. Steven J. Korzeniewski is with the School of Medicine, Wayne State University, Detroit, MI. George Mohler is with the Computer Science Department, Boston College, Chestnut Hill, MA. Jennifer J. Carroll is with the Department of Sociology and Anthropology, North Carolina State University, Raleigh. Brandon del Pozo is with the Warren Alpert School of Medicine, Brown University, Providence, RI. Grant Victor is with the School of Social Work,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brandon","family":"del Pozo","sequence":"additional","affiliation":[{"name":"Bradley Ray is with RTI International, Research Triangle Park, NC. Steven J. Korzeniewski is with the School of Medicine, Wayne State University, Detroit, MI. George Mohler is with the Computer Science Department, Boston College, Chestnut Hill, MA. Jennifer J. Carroll is with the Department of Sociology and Anthropology, North Carolina State University, Raleigh. Brandon del Pozo is with the Warren Alpert School of Medicine, Brown University, Providence, RI. Grant Victor is with the School of Social Work,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grant","family":"Victor","sequence":"additional","affiliation":[{"name":"Bradley Ray is with RTI International, Research Triangle Park, NC. Steven J. Korzeniewski is with the School of Medicine, Wayne State University, Detroit, MI. George Mohler is with the Computer Science Department, Boston College, Chestnut Hill, MA. Jennifer J. Carroll is with the Department of Sociology and Anthropology, North Carolina State University, Raleigh. Brandon del Pozo is with the Warren Alpert School of Medicine, Brown University, Providence, RI. Grant Victor is with the School of Social Work,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip","family":"Huynh","sequence":"additional","affiliation":[{"name":"Bradley Ray is with RTI International, Research Triangle Park, NC. Steven J. Korzeniewski is with the School of Medicine, Wayne State University, Detroit, MI. George Mohler is with the Computer Science Department, Boston College, Chestnut Hill, MA. Jennifer J. Carroll is with the Department of Sociology and Anthropology, North Carolina State University, Raleigh. Brandon del Pozo is with the Warren Alpert School of Medicine, Brown University, Providence, RI. Grant Victor is with the School of Social Work,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bethany J.","family":"Hedden","sequence":"additional","affiliation":[{"name":"Bradley Ray is with RTI International, Research Triangle Park, NC. Steven J. Korzeniewski is with the School of Medicine, Wayne State University, Detroit, MI. George Mohler is with the Computer Science Department, Boston College, Chestnut Hill, MA. Jennifer J. Carroll is with the Department of Sociology and Anthropology, North Carolina State University, Raleigh. Brandon del Pozo is with the Warren Alpert School of Medicine, Brown University, Providence, RI. 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