{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T19:10:49Z","timestamp":1785352249634,"version":"3.55.0"},"reference-count":6,"publisher":"American Public Health Association","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Public Health"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:p> Objective. To examine baseline trends for the 2019 Ending the HIV Epidemic in the United States (EHE), which aims to reduce HIV incidence by 90% by 2030 in the 57 counties and states responsible for half of incident infections, and to provide a counterfactual comparator for future evaluation of the initiative\u2019s midpoint. <\/jats:p><jats:p> Methods. We used 2014\u20122021 metropolitan statistical area (MSA) data to compare HIV diagnostic rate trends between MSAs subsuming EHE regions (n\u2009=\u200946) and other MSAs (n\u2009=\u200976). A difference-in-difference analysis illustrated potential early-stage programmatic effects. <\/jats:p><jats:p> Results. From 2014 to 2021 across 122 MSAs, 305\u2009413 HIV cases were diagnosed with a mean annual MSA-level diagnostic rate change of \u20126.7% (range\u2009=\u2009\u201266.1\u2012466.7%). MSA-level diagnostic rate changed by \u201221.3% (range\u2009=\u2009\u201250.8%\u201214.8%) amongst MSAs including EHE regions and by 2.1% (range\u2009=\u2009\u201266.1%\u2012466.7%) in other MSAs. In a difference-in-difference analysis, the HIV diagnostic rate change from 2020 to 2021 was 3.1 cases per 100\u2009000 people-years ( P\u2009=\u2009.03) greater in EHE regions compared to the baseline HIV diagnostic rate change of \u20120.8 cases per 100\u2009000 people-years ( P\u2009&lt;\u2009.01) across all MSAs. <\/jats:p><jats:p> Conclusions. Although MSAs including EHE regions experienced greater reductions in HIV diagnoses from 2014 to 2021, high interregional variability requires exploration. These trends provide a baseline for subsequent EHE programmatic evaluations. ( Am J Public Health. 2025;115(2):217\u2013220. https:\/\/doi.org\/10.2105\/AJPH.2024.307890 ) <\/jats:p>","DOI":"10.2105\/ajph.2024.307890","type":"journal-article","created":{"date-parts":[[2025,1,8]],"date-time":"2025-01-08T21:02:53Z","timestamp":1736370173000},"page":"217-220","source":"Crossref","is-referenced-by-count":2,"title":["HIV Trends in Metropolitan US Cities From 2014 to 2021: Baseline Data for the Ending the HIV Epidemic Initiative"],"prefix":"10.2105","volume":"115","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4872-0774","authenticated-orcid":false,"given":"Ribhav","family":"Gupta","sequence":"first","affiliation":[{"name":"Ribhav Gupta is with Department of Medicine at the University of Minnesota School of Medicine in Minneapolis and the Department of Epidemiology of Microbial Disease at the Yale School of Public Health in New Haven, CT. Sten H. Vermund is with the Department of Epidemiology of Microbial Disease at the Yale School of Public Health and the Department of Pediatrics at the Yale School of Medicine in New Haven."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7289-8698","authenticated-orcid":false,"given":"Sten H.","family":"Vermund","sequence":"additional","affiliation":[{"name":"Ribhav Gupta is with Department of Medicine at the University of Minnesota School of Medicine in Minneapolis and the Department of Epidemiology of Microbial Disease at the Yale School of Public Health in New Haven, CT. Sten H. Vermund is with the Department of Epidemiology of Microbial Disease at the Yale School of Public Health and the Department of Pediatrics at the Yale School of Medicine in New Haven."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"844","reference":[{"key":"bib2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2019.1343"},{"key":"bib3","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6825a2"},{"key":"bib7","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0000000000002959"},{"key":"bib8","doi-asserted-by":"publisher","DOI":"10.2196\/33522"},{"key":"bib10","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm7125a2"},{"key":"bib11","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0000000000002885"}],"container-title":["American Journal of Public Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/ajph.aphapublications.org\/doi\/pdf\/10.2105\/AJPH.2024.307890","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,8]],"date-time":"2025-01-08T21:03:24Z","timestamp":1736370204000},"score":1,"resource":{"primary":{"URL":"https:\/\/ajph.aphapublications.org\/doi\/full\/10.2105\/AJPH.2024.307890"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2]]},"references-count":6,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,2]]}},"alternative-id":["10.2105\/AJPH.2024.307890"],"URL":"https:\/\/doi.org\/10.2105\/ajph.2024.307890","relation":{},"ISSN":["0090-0036","1541-0048"],"issn-type":[{"value":"0090-0036","type":"print"},{"value":"1541-0048","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2]]}}}