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The cost of the program was balanced against the benefits of the program, such as the averted costs of institutionalization, medical care, and the like. The total cost of the program to screen 100,000 such women was calculated to be $2,047,780, or slightly over $20 per woman screened, while the total economic benefits exceeded $4,000,000. <\/jats:p>","DOI":"10.2105\/ajph.69.6.566","type":"journal-article","created":{"date-parts":[[2008,11,27]],"date-time":"2008-11-27T05:10:13Z","timestamp":1227762613000},"page":"566-573","source":"Crossref","is-referenced-by-count":35,"title":["Maternal serum alpha-fetoprotein screening: a cost-benefit analysis."],"prefix":"10.2105","volume":"69","author":[{"given":"P M","family":"Layde","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S D","family":"von Allmen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr","given":"G P","family":"Oakley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"844","reference":[{"key":"p_1","doi-asserted-by":"crossref","unstructured":"U.K. Collaborative Study: Maternal serum-alpha-fetoprotein measurement in antenatal screening for anencephaly and spina bifida in early pregnancy. 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The Week in Review, The New York Times, September 11, 1977."},{"key":"p_9","first-page":"40","volume":"30","author":"Hagard S","year":"1976","journal-title":"Br J Prev Soc Med"},{"key":"p_10","first-page":"1978","author":"Center for Disease Control","year":"1977","journal-title":"Congenital Malformations Surveillance Report"},{"key":"p_11","first-page":"1","volume":"48","author":"Milunsky A","year":"1976","journal-title":"Obstet Gynecol"},{"key":"p_12","first-page":"6","volume":"48","author":"Milunsky A","year":"1976","journal-title":"Obstet Gynecol"},{"key":"p_13","unstructured":"Klonza EM: Expenditures versus recoverable costs projected \"Screening for Neural-Tube defects\", a conference at for the Maine serum screening program. Paper presented at Scarborough Beach, Maine, September 6-8, 1977."},{"key":"p_14","doi-asserted-by":"publisher","DOI":"10.1136\/adc.46.246.127"},{"key":"p_15","unstructured":"Conley RW: The Economics of Mental Retardation. 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