{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,21]],"date-time":"2025-12-21T17:04:22Z","timestamp":1766336662261},"reference-count":6,"publisher":"American Public Health Association","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Public Health"],"published-print":{"date-parts":[[1992,6]]},"abstract":"<jats:p> BACKGROUND. An observational, epidemiological study was undertaken to evaluate the safety of permethrin 1% creme rinse (Nix) for treatment of head lice infestations. METHODS. Thirty-seven local public health departments enrolled a total of 38,160 patients for 47,578 treatments with permethrin or other pediculicides from September 1, 1986, through January 31, 1988. Follow-up safety information was collected between 7 and 14 days following treatment via return visit or telephone contact. RESULTS. One hundred three adverse events were reported among 41,955 evaluable treatments. The rates of reported adverse events were 2.2 per 1000 treatments among permethrin treatments, 3.4 per 1000 treatments among lindane treatments, and 1.5 per 1000 treatments among other over-the-counter treatments. No serious, unexpected adverse events were detected in the 18,950 patients treated with permethrin. CONCLUSIONS. This study confirmed the safety profile of permethrin in conditions of general use, as seen in clinical trials. Postmarketing safety monitoring in public health departments of drugs used to treat public health conditions was shown to be feasible. <\/jats:p>","DOI":"10.2105\/ajph.82.6.857","type":"journal-article","created":{"date-parts":[[2008,11,29]],"date-time":"2008-11-29T13:17:08Z","timestamp":1227964628000},"page":"857-861","source":"Crossref","is-referenced-by-count":18,"title":["Postmarketing surveillance study of permethrin creme rinse."],"prefix":"10.2105","volume":"82","author":[{"given":"E B","family":"Andrews","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M C","family":"Joseph","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M J","family":"Magenheim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H H","family":"Tilson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P A","family":"Doi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M W","family":"Schultz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"844","reference":[{"key":"p_1","doi-asserted-by":"crossref","unstructured":"Slonka GF, McKinley TW, McCroan JE, etal. Epidemiology of an outbreak of head lice in Georgia.AmJTropMedHyg. 1976;25(5): 739-743.","DOI":"10.4269\/ajtmh.1976.25.739"},{"key":"p_2","unstructured":"Juranek DD. Epidemiologic investigations of pediculosis capitis in school children. In: Orkin M, ed. Scabies and Pediculosis. Philadelphia, Pa, and Toronto, Canada: JR Lippincott Co; 1977:168-173."},{"key":"p_3","doi-asserted-by":"crossref","unstructured":"Slonka GF, Fleissner ML, Berlin J, Puleo J, Harrod EK, Schultz MG. An epidemic of pediculosis capitis. J ParasitoL 1977;63(2): 377-383.","DOI":"10.2307\/3280083"},{"key":"p_4","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.1986.tb00538.x"},{"key":"p_6","first-page":"252","volume":"6","author":"Bowerman JG","year":"1987","journal-title":"Austin RD"},{"issue":"5","key":"p_7","first-page":"598","volume":"48","author":"Strom BL","year":"1990","journal-title":"Phamnacol Ther."}],"container-title":["American Journal of Public Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/ajph.aphapublications.org\/doi\/pdf\/10.2105\/AJPH.82.6.857","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,9]],"date-time":"2022-05-09T18:31:00Z","timestamp":1652121060000},"score":1,"resource":{"primary":{"URL":"https:\/\/ajph.aphapublications.org\/doi\/full\/10.2105\/AJPH.82.6.857"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1992,6]]},"references-count":6,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1992,6]]}},"alternative-id":["10.2105\/AJPH.82.6.857"],"URL":"https:\/\/doi.org\/10.2105\/ajph.82.6.857","relation":{},"ISSN":["0090-0036","1541-0048"],"issn-type":[{"value":"0090-0036","type":"print"},{"value":"1541-0048","type":"electronic"}],"subject":[],"published":{"date-parts":[[1992,6]]}}}