{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,31]],"date-time":"2025-07-31T00:29:30Z","timestamp":1753921770818},"reference-count":25,"publisher":"American Public Health Association","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Public Health"],"published-print":{"date-parts":[[1993,1]]},"abstract":"<jats:p> OBJECTIVES. The goal of the study was to determine survival time after diagnosis of acquired immunodeficiency syndrome (AIDS) and to identify predictors of survival. METHODS. We conducted a population-based prospective survival analysis of all Massachusetts-resident adult AIDS patients diagnosed from January 1, 1979, through December 31, 1988. RESULTS. Median survival was 406 days, with a 5-year survival rate of 3%. Age older than 40 years (P = .001), a diagnosis other than Kaposi's sarcoma (P = .001), and a history of intravenous drug use (P &lt; or = .01) were associated with shorter survival after confounding was controlled. Survival increased as year of diagnosis became more recent (P &lt; .0001). This temporal effect was strongest for patients with Pneumocystis carinii pneumonia. Individuals with Kaposi's sarcoma, Hispanics, homosexual men who were concurrent intravenous drug users, and residents of the greater Boston standard metropolitan statistical area, excluding the city of Boston, did not experience increases in survival over time. CONCLUSIONS. With the exception of cases initially defined by Kaposi's sarcoma, recently diagnosed AIDS case subjects survive longer than those diagnosed earlier in the epidemic. Further work is needed to determine whether this effect is due to lead-time bias or better treatment after diagnosis. <\/jats:p>","DOI":"10.2105\/ajph.83.1.72","type":"journal-article","created":{"date-parts":[[2011,12,2]],"date-time":"2011-12-02T00:59:24Z","timestamp":1322787564000},"page":"72-78","source":"Crossref","is-referenced-by-count":26,"title":["Survival with AIDS in Massachusetts, 1979 to 1989."],"prefix":"10.2105","volume":"83","author":[{"suffix":"3rd","given":"G R","family":"Seage","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Oddleifson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E","family":"Carr","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B","family":"Shea","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L","family":"Makarewicz-Robert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"van Beuzekom","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"De Maria","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"844","reference":[{"key":"p_2","unstructured":"Centers for Disease Control.AIDS Weekly Health and Social Affairs; 1988:208."},{"key":"p_3","unstructured":"Swveillance Report. 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Survival US Dept of Health and Human Services, experience of upstate New York's adult ac-Public Health Service; 1988. TP 71. quired immunodeficiency syndrome cases."},{"key":"p_7","unstructured":"Rothenberg R, Woelfel M, Stonebumer R, In: Fourth International Conference on Acquired Immunodeficiency Syndrome. Abst,cts Volume 2. Stockholm, Sweden: Swedish Ministry of Health and Social Affairs; 1988:209."},{"key":"p_8","unstructured":"Whyte BM, Swanson CE, Cooper DA. Suivival of patients with AIDS in Australia. In: Fouah International Conference on Acquired Immunodeficiency Syndrome. Abstracts Volune 2 Stockholm, Sweden: Swedish Ministry of Health and Social Affairs; 1988:209."},{"key":"p_9","doi-asserted-by":"crossref","unstructured":"Moore RD, Hidalgo J, Sugland BW, Chaisson RE. 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