{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T10:41:24Z","timestamp":1759401684865},"reference-count":15,"publisher":"American Public Health Association","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Public Health"],"published-print":{"date-parts":[[1993,7]]},"abstract":"<jats:p> OBJECTIVES. If Helicobacter pylori plays an important role in the occurrence of three distinct diseases--gastric cancer, gastric ulcer, and duodenal ulcer--their individual epidemiologic behaviors should show a resemblance to one common pattern. METHODS. To test this hypothesis, birth cohort and linear regression analyses were used to study the US temporal and geographic variations, respectively, of mortality from the three diseases. RESULTS. US mortality from gastric ulcer in males and duodenal ulcer in both sexes showed a clear-cut peak of occurrence in subjects born around 1885, whereas gastric cancer declined continuously in all Americans born since 1855. The geographic distributions showed a strong correlation between gastric and duodenal ulcer, as opposed to weak correlations between either ulcer type and gastric cancer. CONCLUSIONS. The similarities in the behavior of the three diseases support the idea that identical risk factors play a crucial role in their occurrence. However, the time lag between the decline in mortality from gastric cancer and the decline in mortality from peptic ulcer and their weak geographic correlations indicate that factors besides H pylori must have influenced their epidemiology. <\/jats:p>","DOI":"10.2105\/ajph.83.7.1006","type":"journal-article","created":{"date-parts":[[2008,11,29]],"date-time":"2008-11-29T13:18:52Z","timestamp":1227964732000},"page":"1006-1010","source":"Crossref","is-referenced-by-count":31,"title":["The US temporal and geographic variations of diseases related to Helicobacter pylori."],"prefix":"10.2105","volume":"83","author":[{"given":"A","family":"Sonnenberg","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"844","reference":[{"key":"p_1","doi-asserted-by":"crossref","unstructured":"Graham DY. Helicobacter pylori: its epidemiology and its role in duodenal ulcer disease. J Gastroenterol HepatoL 1991;6: 105-113.","DOI":"10.1111\/j.1440-1746.1991.tb01448.x"},{"key":"p_2","unstructured":"Graham DY, Klein PD, Evans DG, etal. Helicobacter pylori: epidemiology, relationship to gastric cancer and the role of infants in transmission. Eur J Gastroenterol HepatoL 1992;4(suppl 1):S1-S6."},{"key":"p_3","unstructured":"Catalog ofPublic Use Data Tapes. Washington, DC: US Dept of Health and Human Services; 1988:30-33. DHHS publication PHS 88-1213."},{"key":"p_4","unstructured":"Mortality Statistics-AnnualReport, 1921-1936. Washington, DC: US Bureau of the Census; 1924-1938."},{"key":"p_5","unstructured":"Vital Statistics of the United States. Volume II, Mortality, Part A, 1937-1944. Washington, DC: US Bureau of the Census; 1939-1946."},{"key":"p_6","unstructured":"Vital Statistics of the United States. Volune II, Mortality PartA and B, 1945-1988. Washington, DC: National Center for Health Statistics; 1947-1991."},{"key":"p_7","unstructured":"World Health Organization. Intenaftional Classification of Diseases, 9th Revision. ClinicalModfication. 2nd ed. Washington, DC: US Dept of Health and Human Services; 1980. DHHS publication PHS 80-1260."},{"key":"p_8","unstructured":"US Censu ofPopulation. 1980. Volwne 1, Chapter B. General Population Characteristics. Washington, DC: US Bureau of the Census; 1982."},{"key":"p_9","unstructured":"Kahn HA, Sempos CT. Statistical Methods in Epidemiology. New York, NY: Oxford University Press; 1989:85-105."},{"key":"p_10","unstructured":"Kleinbaum DG, Kupper LL, Muller KE. Applied Regression Analysis and Other Multivariable Methods. 2nd ed. Boston, Mass: PWS-Kent Publishing Co; 1988;219-220."},{"key":"p_11","doi-asserted-by":"publisher","DOI":"10.1002\/sim.4780030205"},{"key":"p_12","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)70433-8"},{"key":"p_13","first-page":"115","author":"Susser M","year":"1962","journal-title":"Lancet."},{"key":"p_14","doi-asserted-by":"crossref","unstructured":"Sonnenberg A, Sengupta A, Bauerfeind P. Epidemiology of peptic ulcer disease. In: ReesWDW, ed.Advancesin UlcerPathogenesis. Lancaster, UK: MTP Press; 1988: 1-22.","DOI":"10.1007\/978-94-009-1245-8_1"},{"key":"p_15","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9681(87)90153-6"}],"container-title":["American Journal of Public Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/ajph.aphapublications.org\/doi\/pdf\/10.2105\/AJPH.83.7.1006","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,9]],"date-time":"2022-05-09T19:25:50Z","timestamp":1652124350000},"score":1,"resource":{"primary":{"URL":"https:\/\/ajph.aphapublications.org\/doi\/full\/10.2105\/AJPH.83.7.1006"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1993,7]]},"references-count":15,"journal-issue":{"issue":"7","published-print":{"date-parts":[[1993,7]]}},"alternative-id":["10.2105\/AJPH.83.7.1006"],"URL":"https:\/\/doi.org\/10.2105\/ajph.83.7.1006","relation":{},"ISSN":["0090-0036","1541-0048"],"issn-type":[{"value":"0090-0036","type":"print"},{"value":"1541-0048","type":"electronic"}],"subject":[],"published":{"date-parts":[[1993,7]]}}}