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All previous discharges of each case or control patient between 1970 and 1990 were searched for the occurrence of hypertensive diseases or chronic diseases of the joints, lungs, pancreas, and liver. The relative frequencies of such diagnoses in case and control patients were compared by multivariate logistic regression. RESULTS: Gastric ulcer and duodenal ulcer, but not gastric cancer, were significantly associated with chronic diseases of the joints, lungs, pancreas, and liver. None of the three diagnoses showed any significant association with hypertensive diseases. CONCLUSIONS: These relationships may reflect the influence of nonsteroidal anti-inflammatory drugs, smoking, and alcohol. They stress the importance of environmental risk factors other than Helicobacter pylori in terms of damage to the upper gastrointestinal mucosa. <\/jats:p>","DOI":"10.2105\/ajph.85.9.1252","type":"journal-article","created":{"date-parts":[[2008,11,29]],"date-time":"2008-11-29T13:18:52Z","timestamp":1227964732000},"page":"1252-1255","source":"Crossref","is-referenced-by-count":18,"title":["Associations of peptic ulcer and gastric cancer with other diseases in US veterans."],"prefix":"10.2105","volume":"85","author":[{"given":"A","family":"Sonnenberg","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I H","family":"Wasserman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"844","reference":[{"key":"p_1","first-page":"1","volume":"174","author":"Westlund K","year":"1963","journal-title":"Acta Med Scand."},{"key":"p_2","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1016\/S0016-5085(19)33679-0","volume":"59","author":"Monson RR","year":"1970","journal-title":"Gastroenterology."},{"key":"p_3","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(76)92790-2"},{"key":"p_4","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1016\/S0016-5085(19)31847-5","volume":"73","author":"Bonnevie 0","year":"1977","journal-title":"Gastroenterology."},{"key":"p_5","doi-asserted-by":"crossref","first-page":"27","DOI":"10.3109\/00365528009182210","volume":"15","author":"Wormsley KG","year":"1980","journal-title":"Scand J Gastroenterol."},{"key":"p_6","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(88)90425-8"},{"key":"p_7","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(88)90288-0"},{"key":"p_8","doi-asserted-by":"crossref","unstructured":"Susser M. 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