{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T23:52:56Z","timestamp":1790898776389,"version":"4.1.0"},"reference-count":24,"publisher":"American Public Health Association","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Public Health"],"published-print":{"date-parts":[[2001,4,1]]},"abstract":"<jats:p> OBJECTIVES: This study explored the risk of childhood acute lymphoblastic leukemia (ALL) associated with participation by household members in hobbies or other home projects involving organic solvents. METHODS: Participants in this case-control study were 640 subjects with ALL and 640 matched controls. RESULTS: Childhood ALL was associated with frequent (&gt; 4 times\/month) exposure to model building (odds ratio [OR] = 1.9; 95% confidence interval [95% CI] = 0.7, 5.8) and artwork using solvents (OR = 4.1; 95% CI = 1.1, 15.1). We also found elevated risk (OR = 1.7; 95% CI = 1.1, 2.7) among children whose mothers lived in homes painted extensively (&gt; 4 rooms) in the year before the children's birth. CONCLUSIONS: In this exploratory study, substantial participation by household members in some common household activities that involve organic solvents was associated with elevated risks of childhood ALL. <\/jats:p>","DOI":"10.2105\/ajph.91.4.564","type":"journal-article","created":{"date-parts":[[2008,11,29]],"date-time":"2008-11-29T13:33:29Z","timestamp":1227965609000},"page":"564-567","source":"Crossref","is-referenced-by-count":57,"title":["Household solvent exposures and childhood acute lymphoblastic leukemia"],"prefix":"10.2105","volume":"91","member":"844","reference":[{"key":"p_1","unstructured":"Chow W-H, Linet MS, Liff JM, Greenberg RS. Cancers in children. In: Schottenfeld D, Fraumeni JF Jr, eds. Cancer Epidemiology and Prevention. New York, NY: Oxford University Press; 1996:1331-1369."},{"key":"p_2","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.98106909"},{"key":"p_3","first-page":"4030","volume":"49","author":"Buckley JD","year":"1989","journal-title":"Cancer Res."},{"key":"p_4","first-page":"98","volume":"28","author":"Fabia J","year":"1974","journal-title":"Br J Prev Soc Med."},{"key":"p_5","doi-asserted-by":"publisher","DOI":"10.1136\/jech.35.1.11"},{"key":"p_6","doi-asserted-by":"publisher","DOI":"10.1080\/00039896.1996.9936022"},{"key":"p_7","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a113992"},{"key":"p_8","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.302.6778.681"},{"key":"p_9","doi-asserted-by":"publisher","DOI":"10.1007\/BF00051656"},{"key":"p_10","first-page":"39","volume":"79","author":"Lowengart RA","year":"1987","journal-title":"J Natl Cancer Inst."},{"key":"p_11","doi-asserted-by":"publisher","DOI":"10.1007\/BF00192164"},{"key":"p_12","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.91957"},{"key":"p_13","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1976.03260300024023"},{"key":"p_14","first-page":"233","volume":"79","author":"Thomas TL","year":"1987","journal-title":"J Natl Cancer Inst."},{"key":"p_15","doi-asserted-by":"publisher","DOI":"10.1097\/00001648-199709000-00017"},{"key":"p_16","doi-asserted-by":"publisher","DOI":"10.1097\/00001648-199805000-00006"},{"key":"p_17","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a113866"},{"key":"p_18","unstructured":"Robison LL, Neglia JP. Epidemiology of Down syndrome and childhood acute leukemia. In: McCoy EE, Epstein CJ, eds. Oncology and Immunology of Down Syndrome. New York, NY: Alan R Liss; 1987:19-32."},{"key":"p_19","doi-asserted-by":"publisher","DOI":"10.5271\/sjweh.2409"},{"key":"p_20","first-page":"783","volume":"8","author":"Shu XO","year":"1999","journal-title":"Cancer Epidemiol Biomarkers Prev."},{"key":"p_21","unstructured":"Linet MS, Cartwright RA. The leukemias. In: Schottenfeld D, Fraumeni JF Jr, eds. Cancer Epidemiology and Prevention. New York, NY: Oxford University Press; 1996:841-892."},{"key":"p_22","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.2830200113"},{"key":"p_23","doi-asserted-by":"publisher","DOI":"10.1023\/A:1018461406120"},{"key":"p_24","doi-asserted-by":"publisher","DOI":"10.3109\/10408449609012525"}],"container-title":["American Journal of Public Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/ajph.aphapublications.org\/doi\/pdf\/10.2105\/AJPH.91.4.564","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,9]],"date-time":"2022-05-09T23:03:16Z","timestamp":1652137396000},"score":1,"resource":{"primary":{"URL":"https:\/\/ajph.aphapublications.org\/doi\/full\/10.2105\/AJPH.91.4.564"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,4,1]]},"references-count":24,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2001,4,1]]}},"alternative-id":["10.2105\/AJPH.91.4.564"],"URL":"https:\/\/doi.org\/10.2105\/ajph.91.4.564","relation":{},"ISSN":["0090-0036","1541-0048"],"issn-type":[{"value":"0090-0036","type":"print"},{"value":"1541-0048","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,4,1]]}}}