{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T00:56:31Z","timestamp":1791420991625,"version":"4.3.3"},"reference-count":17,"publisher":"American Public Health Association","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Public Health"],"published-print":{"date-parts":[[2002,7]]},"abstract":"<jats:p> Objectives. This study examined the methodology of epidemiological studies that suggest use of topical sunscreen preparations is associated with increased risk of malignant melanoma. <\/jats:p><jats:p> Methods. We pooled data from observational studies using a general variance\u2013based meta-analytic method that employed confidence intervals (previously described). The outcome of interest was a summary relative risk (RR) reflecting the risk of melanoma associated with sunscreen use versus nonuse. Sensitivity analyses were performed when necessary to explain any observed statistical heterogeneity. <\/jats:p><jats:p> Results. Combining studies that used nonheterogeneous data yielded a summary RR of 1.01, indicating no association between sunscreen use and development of malignant melanoma. <\/jats:p><jats:p> Conclusions. The available epidemiological data do not support the existence of a relationship between topical sunscreen use and an increased risk of cutaneous malignant melanoma. (Am J Public Health. 2002;92:1173\u20131177) <\/jats:p>","DOI":"10.2105\/ajph.92.7.1173","type":"journal-article","created":{"date-parts":[[2008,12,2]],"date-time":"2008-12-02T00:04:35Z","timestamp":1228176275000},"page":"1173-1177","source":"Crossref","is-referenced-by-count":147,"title":["Use of Topical Sunscreens and the Risk of Malignant Melanoma: A Meta-Analysis of 9067 Patients From 11 Case\u2013Control Studies"],"prefix":"10.2105","volume":"92","author":[{"given":"Michael","family":"Huncharek","sequence":"first","affiliation":[{"name":"Michael Huncharek is with the Division of Radiation Oncology, Department of Clinical Oncology, Marshfield Clinic Cancer Center, Marshfield, Wis; the Meta-Analysis Research Group, Stevens Point, Wis; and St. Michael's Hospital Cancer Center, Stevens Point. Bruce Kupelnick is with the Meta-Analysis Research Group, Stevens Point."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruce","family":"Kupelnick","sequence":"additional","affiliation":[{"name":"Michael Huncharek is with the Division of Radiation Oncology, Department of Clinical Oncology, Marshfield Clinic Cancer Center, Marshfield, Wis; the Meta-Analysis Research Group, Stevens Point, Wis; and St. Michael's Hospital Cancer Center, Stevens Point. 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