{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T18:20:06Z","timestamp":1790187606949,"version":"4.1.0"},"reference-count":22,"publisher":"Korean Society of Otorhinolaryngology-Head and Neck Surgery","issue":"4","license":[{"start":{"date-parts":[[2023,8,23]],"date-time":"2023-08-23T00:00:00Z","timestamp":1692748800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100003710","name":"Korea Health Industry Development Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003710","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003625","name":"Ministry of Health and Welfare","doi-asserted-by":"publisher","award":["HR21C0885"],"award-info":[{"award-number":["HR21C0885"]}],"id":[{"id":"10.13039\/501100003625","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["2022M3E5E908221711"],"award-info":[{"award-number":["2022M3E5E908221711"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100014188","name":"Ministry of Science and ICT","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100014188","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["e-ceo.org"],"crossmark-restriction":true},"short-container-title":["Clin Exp Otorhinolaryngol"],"published-print":{"date-parts":[[2023,11,30]]},"abstract":"<jats:p>Objectives Acute low-tone sensorineural hearing loss (ALHL) is thought to have a different etiology from that of idiopathic sudden sensorineural hearing loss. We hypothesized that endolymphatic hydrops (EH) in the inner ear organ contributes to ALHL, even in patients without vertigo. This study investigated the presence of EH in ALHL and compared the clinical characteristics of patients with or without EH.Methods We retrospectively reviewed 38 patients diagnosed with ALHL without vertigo from January 2017 to March 2022. EH was measured in all patients using inner ear magnetic resonance imaging (MRI). In addition, we selected patients who showed only mid- or high-frequency hearing loss and had available MRI data as a control group and compared the ALHL and control groups.Results After treatment, the pure-tone average at low frequencies significantly improved compared to the initial hearing (P&lt;0.001). Hearing recovery was observed in 63.1% of patients; however, the recovery rate did not differ based on the treatment method. During the follow-up period, six patients (15.8%) progressed to Meniere\u2019s disease, and 18 (47.4%) experienced recurrence. In the ALHL group, the cochlear hydrops ratio on the affected side (0.34\u00b10.09) was significantly higher than on the contralateral side (0.29\u00b10.12) (&lt;i&gt;P&lt;\/i&gt;=0.005), and most patients showed hydrops in the apex area of the cochlea. Compared with the control group (0.25\u00b10.15), the ALHL group showed a significantly higher cochlear hydrops ratio (&lt;i&gt;P&lt;\/i&gt;=0.043). The correlation analysis showed a tendency for hearing thresholds at low frequencies to increase as the hydrops ratio increased, albeit without statistical significance.Conclusion The cochlear hydrops ratio, especially in the apex area on the affected side, was significantly higher in patients with ALHL, suggesting that EH in the cochlea contributes to the pathogenesis of ALHL.<\/jats:p>","DOI":"10.21053\/ceo.2023.00486","type":"journal-article","created":{"date-parts":[[2023,8,23]],"date-time":"2023-08-23T01:53:11Z","timestamp":1692755591000},"page":"334-341","update-policy":"https:\/\/doi.org\/10.21053\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Findings of Intravenous Gadolinium Inner Ear Magnetic Resonance Imaging in Patients With Acute Low-Tone Sensorineural Hearing Loss"],"prefix":"10.21053","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-7795-1498","authenticated-orcid":true,"given":"Hee Won","family":"Seo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9395-4879","authenticated-orcid":true,"given":"Yikyung","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3576-3625","authenticated-orcid":true,"given":"Hyung-Jin","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7157-9935","authenticated-orcid":true,"given":"Won-Ho","family":"Chung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4040-7206","authenticated-orcid":true,"given":"Young Sang","family":"Cho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1894","reference":[{"key":"ref1","first-page":"385","volume-title":"Acute sensorineural hearing loss in low frequencies","author":"Abe","year":"1982"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.21790\/rvs.2018.17.3.102"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1177\/0145561320952501"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2020.102856"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1159\/000506147"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.3342\/kjorl-hns.2019.00759"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.3109\/00016489.2016.1152506"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1177\/000348949710600906"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1007\/bf00180389"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.2463\/mrms.9.237"},{"key":"ref11","first-page":"17562","volume-title":"Usefulness of intravenous gadolinium inner ear mr imaging in diagnosis of Meniere\u2019s disease","author":"Cho","year":"2018"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1080\/00016489.2017.1297539"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1159\/000049079"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1097\/aud.0000000000001129"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.7874\/jao.2021.00269"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1177\/0145561319869610"},{"key":"ref17","first-page":"295","volume-title":"Recurrence rate of idiopathic sudden low-tone sensorineural hearing loss without vertigo: a long-term follow-up study","author":"Fushiki","year":"2009"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1038\/nrdp.2016.28"},{"key":"ref19","first-page":"S71","volume-title":"What is Meniere\u2019s disease? A contemporary re-evaluation of endolymphatic hydrops","author":"Gurkov","year":"2016"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1097\/mao.0b013e3182990e81"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1016\/j.anl.2018.11.008"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1016\/j.anl.2019.04.003"}],"container-title":["Clinical and Experimental Otorhinolaryngology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/e-ceo.org\/upload\/pdf\/ceo-2023-00486.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/e-ceo.org\/journal\/view.php?doi=10.21053\/ceo.2023.00486","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/e-ceo.org\/upload\/pdf\/ceo-2023-00486.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,6]],"date-time":"2023-12-06T03:14:00Z","timestamp":1701832440000},"score":1,"resource":{"primary":{"URL":"http:\/\/e-ceo.org\/journal\/view.php?doi=10.21053\/ceo.2023.00486"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11,30]]},"references-count":22,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,11]]}},"URL":"https:\/\/doi.org\/10.21053\/ceo.2023.00486","relation":{},"ISSN":["1976-8710","2005-0720"],"issn-type":[{"value":"1976-8710","type":"print"},{"value":"2005-0720","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,11,30]]},"assertion":[{"value":"2023-04-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-08-23","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-08-23","order":2,"name":"published","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-11-30","order":3,"name":"published","label":"Print publication","group":{"name":"publication_history","label":"Publication History"}}]}}