{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T03:12:27Z","timestamp":1791947547668,"version":"4.3.4"},"reference-count":24,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Bone and Joint Surgery"],"published-print":{"date-parts":[[2016,4,20]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Osteonecrosis of the femoral head has a host of etiologies. However, in 30% of the cases, no underlying etiology is identified and the process is considered \u201cidiopathic.\u201d Our hypothesis was that osseous anatomical abnormalities might be frequently found in patients with femoral head osteonecrosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>\n                      A retrospective, 1:2 matched, case-control study was undertaken to compare ninety patients with idiopathic osteonecrosis who had undergone lower-limb computed tomography (CT) prior to undergoing total hip arthroplasty with 180 control patients matched for age, sex, and body mass index (BMI) who had undergone lower-limb computed tomography scanning at our radiology department for any reason except articular or bone disease. Preoperative CT scans were performed for all patients to evaluate femoral offset, femoral neck-shaft angle, femoral neck version, femoral head diameter, acetabular coverage estimated with use of the lateral center-edge angle, acetabular version, and acetabular diameter. The mean age was forty-five years, 69% of the patients were men, and the mean BMI was 26 kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Anatomical \u201cabnormalities\u201d associated with osteonecrosis were determined to be a femoral neck-shaft angle of &lt;129\u00b0 (likelihood ratio [LR] = 3.6), femoral neck version of &gt;17\u00b0 (LR = 3.8), a lateral center-edge angle of &lt;32\u00b0 (LR = 5.7), and acetabular version of &lt;19\u00b0 (LR = 1.38). A combination of three of the four anatomical \u201cabnormalities\u201d was found in 73% of the patients with osteonecrosis but only 11% of the control cases (LR = 6).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>This 1:2 matched, anatomical study suggests that acetabular and femoral anatomical factors, in isolation or combination, can be found in a large percentage of cases of \u201cidiopathic\u201d osteonecrosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical Relevance:<\/jats:title>\n                    <jats:p>In this study, isolated or combined abnormalities of the hip were observed in the group of patients with osteonecrosis. Those elements may help surgeons to understand the process underlying idiopathic osteonecrosis and thus require further investigation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2106\/jbjs.14.01099","type":"journal-article","created":{"date-parts":[[2016,4,20]],"date-time":"2016-04-20T14:04:20Z","timestamp":1461161060000},"page":"672-676","source":"Crossref","is-referenced-by-count":25,"title":["Anatomical Findings in Patients Undergoing Total Hip Arthroplasty for Idiopathic Femoral Head Osteonecrosis"],"prefix":"10.2106","volume":"98","author":[{"given":"Matthieu","family":"Ollivier","sequence":"first","affiliation":[{"name":"Department of Orthopedics and Traumatology, St. Marguerite Hospital, Marseille, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandre","family":"Lunebourg","sequence":"additional","affiliation":[{"name":"Department of Orthopedics and Traumatology, St. Marguerite Hospital, Marseille, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew P.","family":"Abdel","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00e9bastien","family":"Parratte","sequence":"additional","affiliation":[{"name":"Department of Orthopedics and Traumatology, St. Marguerite Hospital, Marseille, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-No\u00ebl","family":"Argenson","sequence":"additional","affiliation":[{"name":"Department of Orthopedics and Traumatology, St. Marguerite Hospital, Marseille, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"issue":"3","key":"bib1-20230714","doi-asserted-by":"crossref","first-page":"473","DOI":"10.2106\/00004623-199603000-00022","article-title":"Non-traumatic avascular necrosis of the femoral head","volume":"78","author":"Maillefert","year":"1996","journal-title":"J Bone Joint Surg Am."},{"key":"bib2-20230714","first-page":"143","article-title":"Idiopathic necrosis of the femoral head in adults","volume":"34","author":"Merle d\u2019Aubign\u00e9","year":"1964","journal-title":"Ann R Coll Surg Engl."},{"issue":"2","key":"bib3-20230714","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1007\/s00402-003-0630-9","article-title":"Total hip arthroplasty after avascular necrosis of the femoral head: does etiology affect the results?","volume":"124","author":"Dudkiewicz","year":"2004","journal-title":"Arch Orthop Trauma Surg."},{"issue":"2","key":"bib4-20230714","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1053\/sarh.2002.33724b","article-title":"Pathogenesis and natural history of osteonecrosis","volume":"32","author":"Assouline-Dayan","year":"2002","journal-title":"Semin Arthritis Rheum."},{"issue":"7","key":"bib5-20230714","first-page":"327","article-title":"Avascular necrosis of the femoral head: etiology, pathophysiology, classification, and current treatment guidelines","volume":"33","author":"Aldridge","year":"2004","journal-title":"Am J Orthop (Belle Mead NJ)."},{"issue":"6","key":"bib6-20230714","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1055\/s-2008-1040311","article-title":"[In vivo measurement of hip joint stress. 1. Physical therapy]","volume":"127","author":"Bergmann","year":"1989","journal-title":"Z Orthop Ihre Grenzgeb."},{"issue":"9","key":"bib7-20230714","first-page":"767","article-title":"[The role of mechanical stress on the femoral head in the occurrence of femoral head lesions in spontaneously hypertensive rats]","volume":"65","author":"Nishimura","year":"1991","journal-title":"Nihon Seikeigeka Gakkai Zasshi."},{"issue":"24","key":"bib8-20230714","doi-asserted-by":"crossref","first-page":"2228","DOI":"10.2106\/JBJS.L.00300","article-title":"Effects of non-weight-bearing on the immature femoral head following ischemic osteonecrosis: an experimental investigation in immature pigs","volume":"94","author":"Kim","year":"2012","journal-title":"J Bone Joint Surg Am."},{"issue":"5","key":"bib9-20230714","doi-asserted-by":"crossref","first-page":"051008","DOI":"10.1115\/1.2953472","article-title":"Validation of finite element predictions of cartilage contact pressure in the human hip joint","volume":"130","author":"Anderson","year":"2008","journal-title":"J Biomech Eng."},{"issue":"1","key":"bib10-20230714","first-page":"41","article-title":"[Anatomo-clinical (radiological and etiological) forms of so-called primary chronic ischemia and osteonecrosis of the upper femoral epiphysis]","volume":"38","author":"Arlet","year":"1971","journal-title":"Rev Rhum Mal Osteoartic."},{"issue":"5","key":"bib11-20230714","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1016\/j.otsr.2013.02.006","article-title":"Relation between lower extremity alignment and proximal femur anatomy. 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