{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T02:11:34Z","timestamp":1793239894719,"version":"4.5.0"},"reference-count":40,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Bone and Joint Surgery"],"published-print":{"date-parts":[[2017,1,4]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Current literature describing the periacetabular osteotomy (PAO) is mostly limited to retrospective case series. Larger, prospective cohort studies are needed to provide better clinical evidence regarding this procedure. The goals of the current study were to (1) report minimum 2-year patient-reported outcomes (pain, hip function, activity, overall health, and quality of life), (2) investigate preoperative clinical and disease characteristics as predictors of clinical outcomes, and (3) report the rate of early failures and reoperations in patients undergoing contemporary PAO surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A large, prospective, multicenter cohort of PAO procedures was established, and outcomes at a minimum of 2 years were analyzed. A total of 391 hips were included for analysis (79% of the patients were female, and the average patient age was 25.4 years). Patient-reported outcomes, conversion to total hip replacement, reoperations, and major complications were documented. Variables with a p value of \u22640.10 in the univariate linear regressions were included in the multivariate linear regression. The backward stepwise selection method was used to determine the final risk factors of clinical outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Clinical outcome analysis demonstrated major clinically important improvements in pain, function, quality of life, overall health, and activity level. Increasing age and a body mass index status of overweight or obese were predictive of improved results for certain outcome metrics. Male sex and mild acetabular dysplasia were predictive of lesser improvements in certain outcome measures. Three (0.8%) of the hips underwent early conversion to total hip arthroplasty, 12 (3%) required reoperation, and 26 (7%) experienced a major complication.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>This large, prospective cohort study demonstrated the clinical success of contemporary PAO surgery for the treatment of symptomatic acetabular dysplasia. Patient and disease characteristics demonstrated predictive value that should be considered in surgical decision-making.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence:<\/jats:title>\n                    <jats:p>\n                      Therapeutic\n                      <jats:underline>Level IV<\/jats:underline>\n                      . See Instructions for Authors for a complete description of levels of evidence.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.2106\/jbjs.15.00798","type":"journal-article","created":{"date-parts":[[2017,1,6]],"date-time":"2017-01-06T01:19:12Z","timestamp":1483665552000},"page":"33-41","source":"Crossref","is-referenced-by-count":244,"title":["Patient-Reported Outcomes of Periacetabular Osteotomy from the Prospective ANCHOR Cohort Study"],"prefix":"10.2106","volume":"99","author":[{"given":"John C.","family":"Clohisy","sequence":"first","affiliation":[{"name":"Departments of Orthopaedic Surgery (J.C.C. and G.B.) and Biostatistics (J.B.), Washington University School of Medicine, St. Louis, Missouri"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey","family":"Ackerman","sequence":"additional","affiliation":[{"name":"Illinois Bone & Joint Institute, Chicago, Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geneva","family":"Baca","sequence":"additional","affiliation":[{"name":"Departments of Orthopaedic Surgery (J.C.C. and G.B.) and Biostatistics (J.B.), Washington University School of Medicine, St. Louis, Missouri"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jack","family":"Baty","sequence":"additional","affiliation":[{"name":"Departments of Orthopaedic Surgery (J.C.C. and G.B.) and Biostatistics (J.B.), Washington University School of Medicine, St. Louis, Missouri"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul E.","family":"Beaul\u00e9","sequence":"additional","affiliation":[{"name":"Ottawa General Hospital, Ottawa, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young-Jo","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Boston Children\u2019s Hospital, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael B.","family":"Millis","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Boston Children\u2019s Hospital, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David A.","family":"Podeszwa","sequence":"additional","affiliation":[{"name":"Texas Scottish Rite Hospital, Dallas, Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Perry L.","family":"Schoenecker","sequence":"additional","affiliation":[{"name":"Shriners Hospitals for Children, St. Louis, Missouri"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafael J.","family":"Sierra","sequence":"additional","affiliation":[{"name":"Mayo Clinic, Rochester, Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ernest L.","family":"Sink","sequence":"additional","affiliation":[{"name":"Hospital for Special Surgery, New York, NY"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel J.","family":"Sucato","sequence":"additional","affiliation":[{"name":"Texas Scottish Rite Hospital, Dallas, Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert T.","family":"Trousdale","sequence":"additional","affiliation":[{"name":"Mayo Clinic, Rochester, Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ira","family":"Zaltz","sequence":"additional","affiliation":[{"name":"Beaumont Hospital, Royal Oak, Michigan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"on behalf of the ANCHOR Study Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"issue":"9","key":"bib1-20230810","doi-asserted-by":"crossref","first-page":"2221","DOI":"10.1007\/s11999-009-0810-1","article-title":"Combined periacetabular and femoral osteotomies for severe hip deformities","volume":"467","author":"Clohisy","year":"2009","journal-title":"Clin Orthop Relat Res."},{"key":"bib2-20230810","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1097\/00003086-198807000-00006","article-title":"A new periacetabular osteotomy for the treatment of hip dysplasias. 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