{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T18:03:43Z","timestamp":1791482623116,"version":"4.3.4"},"reference-count":16,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Bone and Joint Surgery"],"published-print":{"date-parts":[[2017,3,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Despite the large increase in total hip arthroplasties and total knee arthroplasties, the incidence and prevalence of additional contralateral or ipsilateral joint arthroplasty are poorly understood. The purpose of this study was to determine the rate of additional joint arthroplasty after a primary total hip arthroplasty or total knee arthroplasty.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This historical cohort study identified population-based cohorts of patients who underwent primary total hip arthroplasty (n = 1,933) or total knee arthroplasty (n = 2,139) between 1969 and 2008. Patients underwent passive follow-up through their medical records beginning with the primary total hip arthroplasty or total knee arthroplasty. We assessed the likelihood of undergoing a subsequent total joint arthroplasty, including simultaneous and staged bilateral procedures. Age, sex, and calendar year were evaluated as potential predictors of subsequent arthroplasty.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>During a mean follow-up of 12 years after an initial total hip arthroplasty, we observed 422 contralateral total hip arthroplasties (29% at 20 years), 76 contralateral total knee arthroplasties (6% at 10 years), and 32 ipsilateral total knee arthroplasties (2% at 20 years). Younger age was a significant predictor of contralateral total hip arthroplasty (p &lt; 0.0001), but not a predictor of the subsequent risk of total knee arthroplasty. During a mean follow-up of 11 years after an initial total knee arthroplasty, we observed 809 contralateral total knee arthroplasties (45% at 20 years), 31 contralateral total hip arthroplasties (3% at 20 years), and 29 ipsilateral total hip arthroplasties (2% at 20 years). Older age was a significant predictor of ipsilateral or contralateral total hip arthroplasty (p &lt; 0.001).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Patients undergoing total hip arthroplasty or total knee arthroplasty can be informed of a 30% to 45% chance of a surgical procedure in a contralateral cognate joint and about a 5% chance of a surgical procedure in noncognate joints within 20 years of initial arthroplasty. Increased risk of contralateral total knee arthroplasty following an initial total hip arthroplasty may be due to gait changes prior to and\/or following total hip arthroplasty. The higher prevalence of bilateral total hip arthroplasty in younger patients may result from bilateral disease processes that selectively affect the young hip, such as osteonecrosis, or structural hip problems, such as acetabular dysplasia or femoroacetabular impingement.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence:<\/jats:title>\n                    <jats:p>\n                      Therapeutic\n                      <jats:underline>Level IV<\/jats:underline>\n                      . See Instructions for Authors for a complete description of levels of evidence.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.2106\/jbjs.16.00499","type":"journal-article","created":{"date-parts":[[2017,3,1]],"date-time":"2017-03-01T08:41:56Z","timestamp":1488357716000},"page":"396-401","source":"Crossref","is-referenced-by-count":76,"title":["Subsequent Total Joint Arthroplasty After Primary Total Knee or Hip Arthroplasty"],"prefix":"10.2106","volume":"99","author":[{"given":"Thomas L.","family":"Sanders","sequence":"first","affiliation":[{"name":"Departments of Orthopedic Surgery (T.L.S., H.M.K., and D.J.B.) and Health Sciences Research (H.M.K., C.D.S., and D.R.L.), Mayo Clinic, Rochester, Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hilal","family":"Maradit Kremers","sequence":"additional","affiliation":[{"name":"Departments of Orthopedic Surgery (T.L.S., H.M.K., and D.J.B.) and Health Sciences Research (H.M.K., C.D.S., and D.R.L.), Mayo Clinic, Rochester, Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cathy D.","family":"Schleck","sequence":"additional","affiliation":[{"name":"Departments of Orthopedic Surgery (T.L.S., H.M.K., and D.J.B.) and Health Sciences Research (H.M.K., C.D.S., and D.R.L.), Mayo Clinic, Rochester, Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dirk R.","family":"Larson","sequence":"additional","affiliation":[{"name":"Departments of Orthopedic Surgery (T.L.S., H.M.K., and D.J.B.) and Health Sciences Research (H.M.K., C.D.S., and D.R.L.), Mayo Clinic, Rochester, Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel J.","family":"Berry","sequence":"additional","affiliation":[{"name":"Departments of Orthopedic Surgery (T.L.S., H.M.K., and D.J.B.) and Health Sciences Research (H.M.K., C.D.S., and D.R.L.), Mayo Clinic, Rochester, Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"issue":"17","key":"bib1-20230810","doi-asserted-by":"crossref","first-page":"1386","DOI":"10.2106\/JBJS.N.01141","article-title":"Prevalence of total hip and knee replacement in the United States","volume":"97","author":"Maradit Kremers","year":"2015","journal-title":"J Bone Joint Surg Am."},{"issue":"4","key":"bib2-20230810","doi-asserted-by":"crossref","first-page":"780","DOI":"10.2106\/00004623-200704000-00012","article-title":"Projections of primary and revision hip and knee arthroplasty in the United States from 2005 to 2030","volume":"89","author":"Kurtz","year":"2007","journal-title":"J Bone Joint Surg Am."},{"issue":"10","key":"bib3-20230810","doi-asserted-by":"crossref","first-page":"1842","DOI":"10.1016\/j.arth.2012.10.008","article-title":"The fate of the remaining knee(s) or hip(s) in osteoarthritic patients undergoing a primary TKA or THA","volume":"28","author":"Shao","year":"2013","journal-title":"J Arthroplasty."},{"issue":"8","key":"bib4-20230810","first-page":"E141","article-title":"Joint arthroplasty within 10 years after primary Charnley total hip arthroplasty","volume":"38","author":"Sayeed","year":"2009","journal-title":"Am J Orthop (Belle Mead NJ)."},{"issue":"4","key":"bib5-20230810","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/0883-5403(94)90043-4","article-title":"Long-term outcomes of contralateral knees after unilateral total knee arthroplasty for osteoarthritis","volume":"9","author":"Ritter","year":"1994","journal-title":"J Arthroplasty."},{"issue":"8","key":"bib6-20230810","first-page":"1822","article-title":"The risk of contralateral total knee arthroplasty after knee replacement for osteoarthritis","volume":"30","author":"McMahon","year":"2003","journal-title":"J Rheumatol."},{"issue":"7","key":"bib7-20230810","doi-asserted-by":"crossref","first-page":"1144","DOI":"10.1016\/j.joca.2015.03.022","article-title":"Relationship of unilateral total hip arthroplasty (THA) to contralateral and ipsilateral knee joint degeneration \u2013 a longitudinal 3T MRI study from the Osteoarthritis Initiative (OAI)","volume":"23","author":"Jungman","year":"2015","journal-title":"Osteoarthritis Cartilage."},{"issue":"3","key":"bib8-20230810","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/j.joca.2012.12.008","article-title":"The progression of end-stage osteoarthritis: analysis of data from the Australian and Norwegian joint replacement registries using a multi-state model","volume":"21","author":"Gillam","year":"2013","journal-title":"Osteoarthritis Cartilage."},{"issue":"12","key":"bib9-20230810","doi-asserted-by":"crossref","first-page":"1202","DOI":"10.1016\/j.mayocp.2012.08.012","article-title":"History of the Rochester Epidemiology Project: half a century of medical records linkage in a US population","volume":"87","author":"Rocca","year":"2012","journal-title":"Mayo Clin Proc."},{"issue":"2","key":"bib10-20230810","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.mayocp.2011.11.009","article-title":"Generalizability of epidemiological findings and public health decisions: an illustration from the Rochester Epidemiology Project","volume":"87","author":"St Sauver","year":"2012","journal-title":"Mayo Clin Proc."},{"issue":"6","key":"bib11-20230810","doi-asserted-by":"crossref","first-page":"1614","DOI":"10.1093\/ije\/dys195","article-title":"Data resource profile: the Rochester Epidemiology Project (REP) medical records-linkage system","volume":"41","author":"St Sauver","year":"2012","journal-title":"Int J Epidemiol."},{"issue":"9","key":"bib12-20230810","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1093\/aje\/kwq482","article-title":"Use of a medical records linkage system to enumerate a dynamic population over time: the Rochester Epidemiology Project","volume":"173","author":"St Sauver","year":"2011","journal-title":"Am J Epidemiol."},{"issue":"6","key":"bib13-20230810","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1186\/s13075-014-0455-7","article-title":"Asymmetries and relationships between dynamic loading, muscle strength, and proprioceptive acuity at the knees in symptomatic unilateral hip osteoarthritis","volume":"16","author":"Shakoor","year":"2014","journal-title":"Arthritis Res Ther."},{"issue":"5","key":"bib14-20230810","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1002\/jor.21323","article-title":"Gait after unilateral total knee arthroplasty: frontal plane analysis","volume":"29","author":"Alnahdi","year":"2011","journal-title":"J Orthop Res."},{"issue":"10","key":"bib15-20230810","doi-asserted-by":"crossref","first-page":"1965","DOI":"10.1016\/j.apmr.2008.02.034","article-title":"Bilateral frontal plane mechanics after unilateral total knee arthroplasty","volume":"89","author":"Milner","year":"2008","journal-title":"Arch Phys Med Rehabil."},{"issue":"8","key":"bib16-20230810","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1016\/j.clinbiomech.2013.07.014","article-title":"Joint loading asymmetries in knee replacement patients observed both pre- and six months post-operation","volume":"28","author":"Worsley","year":"2013","journal-title":"Clin Biomech (Bristol, Avon)."}],"container-title":["Journal of Bone and Joint Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/00004623-201703010-00005","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T13:38:28Z","timestamp":1787751508000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00004623-201703010-00005"}},"subtitle":["A 40-Year Population-Based Study"],"short-title":[],"issued":{"date-parts":[[2017,3,1]]},"references-count":16,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2017]]}},"URL":"https:\/\/doi.org\/10.2106\/jbjs.16.00499","relation":{},"ISSN":["0021-9355","1535-1386"],"issn-type":[{"value":"0021-9355","type":"print"},{"value":"1535-1386","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,3,1]]}}}