{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T17:39:27Z","timestamp":1791049167667,"version":"4.1.0"},"reference-count":49,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"20","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,10,19]]},"abstract":"Update<\/jats:title>\n \n This article was updated on October 19, 2022, because of previous errors, which were discovered after the preliminary version of the article was posted online. On page 1787, in the legend for Figure 2, the sentence that had read \u201cThe vertebral collapse rate (in %) was defined as 1 \u2212 (A\/P) \u00d7 100, and vertebral instability (in %) was defined as the difference in vertebral collapse rate between the loaded and non-loaded images.\u201d now reads \u201cThe vertebral collapse rate (in %) was defined as (1 \u2212 [A\/P]) \u00d7 100, and vertebral instability (in %) was defined as the difference in vertebral collapse rate between the loaded and non-loaded images.\u201d On page 1788, in the section entitled \u201cData Collection,\u201d the sentence that had read \u201cThe vertebral collapse rate (in %) was defined as 1 \u2212 (anterior vertebral wall height\/posterior vertebral wall height) \u00d7 100, and vertebral instability (in %) was defined as the difference in vertebral collapse rate between the loaded and non-loaded images\n 9<\/jats:sup>\n .\u201d now reads \u201cThe vertebral collapse rate (in %) was defined as (1 \u2212 [anterior vertebral wall height\/posterior vertebral wall height]) \u00d7 100, and vertebral instability (in %) was defined as the difference in vertebral collapse rate between the loaded and non-loaded images\n 9<\/jats:sup>\n .\u201d Finally, on page 1791, in Table IV, the footnote for the \u201cPrimary outcome\u201d row that had read \u201cN = 113 in the rest group and 99 in the no-rest group.\u201d now reads \u201cN = 116 in the rest group and 108 in the no-rest group.\u201d\n <\/jats:p>\n \n Background:<\/jats:title>\n Although imaging findings that predict resistance to conservative treatment in patients with osteoporotic vertebral fracture (OVF) have recently been reported, no conservative treatment method has been standardized. In this study, the effects of initial bed rest on the outcomes of patients with OVF and in patients with and without poor prognostic findings on magnetic resonance imaging (MRI) were compared.<\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n This prospective cohort study at 2 facilities involved consecutive patients aged \u226565 years with OVF who began treatment within 2 weeks after their injury and were observed for 6 months. Patients at one hospital rested for 2 weeks (116 patients; mean age, 80.4 years), whereas those at the other hospital were not instructed to rest (108 patients; mean age, 81.5 years). Patients were further divided according to the presence or absence of poor prognostic MRI findings. The primary end point was the rate of transition to surgery; secondary end points included bone union rate, vertebral collapse progression, local kyphosis progression, and changes in activities of daily living (ADL).<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n Forty-five patients in the rest group (including 3 who required surgery) and 37 patients in the no-rest group (including 9 who required surgery) had poor prognostic MRI findings. Although the difference in the rate of transition to surgery between the rest and no-rest groups did not reach significance among all patients (p = 0.06), the transition rate in the rest group was significantly lower (p = 0.02) in the patients with poor prognostic MRI findings. Both the bone union rate and changes in ADL were not significantly different between the rest and no-rest groups. The mean vertebral collapse progression was 6.4% in the rest group and 20.9% in the no-rest group (p < 0.001), and the mean local kyphosis progression was 2.4\u00b0 in the rest group and 8.8\u00b0 in the no-rest group (p < 0.001).<\/jats:p>\n <\/jats:sec>\n \n Conclusions:<\/jats:title>\n Although bed rest is not recommended for all patients, hospitalized bed rest for 2 weeks reduced the number of patients with OVF who require surgery among patients with poor prognostic MRI findings. Bed rest also reduced progression of vertebral collapse and kyphosis, regardless of the MRI findings.<\/jats:p>\n <\/jats:sec>\n \n Level of Evidence:<\/jats:title>\n \n Therapeutic\n Level II<\/jats:underline>\n . See Instructions for Authors for a complete description of levels of evidence.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.2106\/jbjs.22.00116","type":"journal-article","created":{"date-parts":[[2022,8,25]],"date-time":"2022-08-25T08:01:45Z","timestamp":1661414505000},"page":"1785-1795","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":16,"title":["Therapeutic Effects of Conservative Treatment with 2-Week Bed Rest for Osteoporotic Vertebral Fractures"],"prefix":"10.2106","volume":"104","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7325-4357","authenticated-orcid":false,"given":"Toru","family":"Funayama","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3679-9438","authenticated-orcid":false,"given":"Masaki","family":"Tatsumura","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery and Sports Medicine, Tsukuba University Hospital Mito Clinical Education and Training Center, Mito Kyodo General Hospital, Mito, Ibaraki, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4450-0819","authenticated-orcid":false,"given":"Kengo","family":"Fujii","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Kenpoku Medical Center Takahagi Kyodo Hospital, Takahagi, Ibaraki, Japan"},{"name":"Department of Orthopaedic Surgery, Showa General Hospital, Kodaira, Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6034-1593","authenticated-orcid":false,"given":"Akira","family":"Ikumi","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery and Sports Medicine, Tsukuba University Hospital Mito Clinical Education and Training Center, Mito Kyodo General Hospital, Mito, Ibaraki, Japan"},{"name":"Department of Orthopaedic Surgery, Kenpoku Medical Center Takahagi Kyodo Hospital, Takahagi, Ibaraki, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9614-5399","authenticated-orcid":false,"given":"Shun","family":"Okuwaki","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan"},{"name":"Department of Orthopaedic Surgery, Kenpoku Medical Center Takahagi Kyodo Hospital, Takahagi, Ibaraki, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5789-993X","authenticated-orcid":false,"given":"Yosuke","family":"Shibao","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0982-5386","authenticated-orcid":false,"given":"Masao","family":"Koda","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9293-3531","authenticated-orcid":false,"given":"Masashi","family":"Yamazaki","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"the Tsukuba Spine Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2022,8,24]]},"reference":[{"issue":"3","key":"bib1-20250430","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1007\/s00198-020-05804-3","article-title":"Vertebral fracture: epidemiology, impact and use of DXA vertebral fracture assessment in fracture liaison services","volume":"32","author":"Lems","year":"2021","journal-title":"Osteoporos Int."},{"issue":"5","key":"bib2-20250430","doi-asserted-by":"crossref","first-page":"505S","DOI":"10.1016\/8756-3282(95)00258-4","article-title":"The worldwide problem of osteoporosis: insights afforded by epidemiology","volume":"17","author":"Riggs","year":"1995","journal-title":"Bone."},{"issue":"3","key":"bib3-20250430","doi-asserted-by":"crossref","first-page":"144","DOI":"10.14245\/kjs.2013.10.3.144","article-title":"Comparative study on the period of absolute bed rest of vertebral compression fracture","volume":"10","author":"Cha","year":"2013","journal-title":"Korean J Spine."},{"issue":"11","key":"bib4-20250430","doi-asserted-by":"crossref","first-page":"E641","DOI":"10.1097\/BRS.0b013e31828ced9d","article-title":"Impact of initial conservative treatment interventions on the outcomes of patients with osteoporotic vertebral fractures","volume":"38","author":"Hoshino","year":"2013","journal-title":"Spine (Phila Pa 1976)."},{"issue":"2","key":"bib5-20250430","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.jcot.2017.02.001","article-title":"Non-surgical management of acute osteoporotic vertebral compression fracture: A review","volume":"8","author":"Garg","year":"2017","journal-title":"J Clin Orthop Trauma."},{"issue":"2","key":"bib6-20250430","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1302\/0301-620X.94B2.26894","article-title":"Conservative management of patients with an osteoporotic vertebral fracture: a review of the literature","volume":"94","author":"Longo","year":"2012","journal-title":"J Bone Joint Surg Br."},{"issue":"12","key":"bib7-20250430","doi-asserted-by":"crossref","first-page":"1932","DOI":"10.1016\/j.spinee.2017.07.174","article-title":"An overview of clinical guidelines for the management of vertebral compression fracture: a systematic review","volume":"17","author":"Parreira","year":"2017","journal-title":"Spine J."},{"issue":"1","key":"bib8-20250430","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1007\/s00068-016-0747-5","article-title":"Conservative management of osteoporotic vertebral fractures: an update","volume":"43","author":"Slavici","year":"2017","journal-title":"Eur J Trauma Emerg Surg."},{"issue":"2","key":"bib9-20250430","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1016\/j.jos.2021.01.005","article-title":"Characteristic imaging findings predicting the risk of conservative treatment resistance in fresh osteoporotic vertebral fractures with poor prognostic features on magnetic resonance imaging","volume":"27","author":"Funayama","year":"2022","journal-title":"J Orthop Sci."},{"issue":"13","key":"bib10-20250430","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1097\/BRS.0000000000003413","article-title":"Risk factors of nonunion after acute osteoporotic vertebral fractures: A prospective multicenter cohort study","volume":"45","author":"Inose","year":"2020","journal-title":"Spine (Phila Pa 1976)."},{"issue":"2","key":"bib11-20250430","doi-asserted-by":"crossref","first-page":"E61","DOI":"10.1097\/BSD.0b013e318292b509","article-title":"Usefulness of an early MRI-based classification system for predicting vertebral collapse and pseudoarthrosis after osteoporotic vertebral fractures","volume":"27","author":"Kanchiku","year":"2014","journal-title":"J Spinal Disord Tech."},{"issue":"10","key":"bib12-20250430","doi-asserted-by":"crossref","first-page":"2565","DOI":"10.1007\/s00586-017-5340-z","article-title":"Osteoporotic vertebral fractures: predictive factors for conservative treatment failure. A systematic review","volume":"27","author":"Muratore","year":"2018","journal-title":"Eur Spine J."},{"issue":"4","key":"bib13-20250430","doi-asserted-by":"crossref","first-page":"641","DOI":"10.14444\/7084","article-title":"Can we predict the progression of vertebral collapse in conservative treatment of osteoporotic vertebral fractures? A 3-year retrospective study of 180 patients from the emergency department","volume":"14","author":"Muratore","year":"2020","journal-title":"Int J Spine Surg."},{"issue":"1","key":"bib14-20250430","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1186\/s13018-020-01649-y","article-title":"Vertebral mobility is a valuable indicator for predicting and determining bone union in osteoporotic vertebral fractures: a conventional observation study","volume":"15","author":"Sato","year":"2020","journal-title":"J Orthop Surg Res."},{"issue":"12","key":"bib15-20250430","doi-asserted-by":"crossref","first-page":"3567","DOI":"10.1007\/s00198-016-3687-3","article-title":"Predicting delayed union in osteoporotic vertebral fractures with consecutive magnetic resonance imaging in the acute phase: a multicenter cohort study","volume":"27","author":"Takahashi","year":"2016","journal-title":"Osteoporos Int."},{"issue":"15","key":"bib16-20250430","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1097\/BRS.0b013e3181f29e8d","article-title":"Characteristic radiographic or magnetic resonance images of fresh osteoporotic vertebral fractures predicting potential risk for nonunion: a prospective multicenter study","volume":"36","author":"Tsujio","year":"2011","journal-title":"Spine (Phila Pa 1976)."},{"issue":"Suppl 3","key":"bib17-20250430","doi-asserted-by":"crossref","first-page":"S26","DOI":"10.1016\/j.injury.2018.10.006","article-title":"The impact of magnetic resonance imaging in the diagnostic and classification process of osteoporotic vertebral fractures","volume":"49","author":"Marongiu","year":"2018","journal-title":"Injury."},{"issue":"21","key":"bib18-20250430","doi-asserted-by":"crossref","first-page":"2430","DOI":"10.1097\/01.brs.0000184303.86932.77","article-title":"\u201cOccult\u201d osteoporotic vertebral fractures: vertebral body fractures without radiologic collapse","volume":"30","author":"Pham","year":"2005","journal-title":"Spine (Phila Pa 1976)."},{"issue":"3","key":"bib19-20250430","doi-asserted-by":"crossref","first-page":"176","DOI":"10.5435\/00124635-201103000-00007","article-title":"The treatment of symptomatic osteoporotic spinal compression fractures","volume":"19","author":"Esses","year":"2011","journal-title":"J Am Acad Orthop Surg."},{"key":"bib20-20250430","doi-asserted-by":"crossref","first-page":"373","DOI":"10.2147\/IJGM.S25972","article-title":"Initial non-weight-bearing therapy is important for preventing vertebral body collapse in elderly patients with clinical vertebral fractures","volume":"5","author":"Kishikawa","year":"2012","journal-title":"Int J Gen Med."},{"issue":"1","key":"bib21-20250430","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1007\/s11657-018-0547-0","article-title":"Initial hospitalization with rigorous bed rest followed by bracing and rehabilitation as an option of conservative treatment for osteoporotic vertebral fractures in elderly patients: a pilot one arm safety and feasibility study","volume":"13","author":"Abe","year":"2018","journal-title":"Arch Osteoporos."},{"issue":"4","key":"bib22-20250430","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1007\/s00774-014-0604-8","article-title":"Factors affecting postoperative activities of daily living in patients with osteoporotic vertebral collapse with neurological deficits","volume":"33","author":"Kashii","year":"2015","journal-title":"J Bone Miner Metab."},{"issue":"7","key":"bib23-20250430","doi-asserted-by":"crossref","first-page":"1633","DOI":"10.1007\/s00586-013-2759-8","article-title":"Surgical treatment for osteoporotic vertebral collapse with neurological deficits: retrospective comparative study of three procedures\u2014anterior surgery versus posterior spinal shorting osteotomy versus posterior spinal fusion using vertebroplasty","volume":"22","author":"Kashii","year":"2013","journal-title":"Eur Spine J."},{"issue":"13","key":"bib24-20250430","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1097\/BRS.0b013e3182432823","article-title":"Prognostic factors for reduction of activities of daily living following osteoporotic vertebral fractures","volume":"37","author":"Matsumoto","year":"2012","journal-title":"Spine (Phila Pa 1976)."},{"issue":"1","key":"bib25-20250430","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/s11657-017-0411-7","article-title":"Difference of clinical course between cases with bone union and those with delayed union following osteoporotic vertebral fractures","volume":"13","author":"Yasuda","year":"2017","journal-title":"Arch Osteoporos."},{"issue":"1","key":"bib26-20250430","doi-asserted-by":"crossref","first-page":"51","DOI":"10.22603\/ssrr.2021-0029","article-title":"Relationship between vertebral instability and the cross-sectional area of lumbar muscles in postmenopausal acute osteoporotic vertebral fractures","volume":"6","author":"Okuwaki","year":"2021","journal-title":"Spine Surg Relat Res."},{"issue":"4","key":"bib27-20250430","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1007\/s00198-012-2048-0","article-title":"Degenerative changes at the lumbar spine\u2014implications for bone mineral density measurement in elderly women","volume":"24","author":"Tenne","year":"2013","journal-title":"Osteoporos Int."},{"issue":"2","key":"bib28-20250430","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1007\/s00198-013-2456-9","article-title":"Efficacy of the dynamic radiographs for diagnosing acute osteoporotic vertebral fractures","volume":"25","author":"Niimi","year":"2014","journal-title":"Osteoporos Int."},{"issue":"2","key":"bib29-20250430","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1007\/s00774-021-01283-6","article-title":"Risk factors affecting vertebral collapse and kyphotic progression in postmenopausal osteoporotic vertebral fractures","volume":"40","author":"Okuwaki","year":"2022","journal-title":"J Bone Miner Metab."},{"issue":"3","key":"bib30-20250430","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1038\/bmt.2012.244","article-title":"Investigation of the freely available easy-to-use software \u2018EZR\u2019 for medical statistics","volume":"48","author":"Kanda","year":"2013","journal-title":"Bone Marrow Transplant."},{"key":"bib31-20250430","first-page":"1428","article-title":"Complications of immobilization and bed rest. Part 1: Musculoskeletal and cardiovascular complications","volume":"39","author":"Dittmer","year":"1993","journal-title":"Can Fam Physician."},{"issue":"5","key":"bib32-20250430","first-page":"709","article-title":"[Secondary osteoporosis UPDATE. Bone loss due to bed rest and human space flight study]","volume":"20","author":"Ohshima","year":"2010","journal-title":"Clin Calcium."},{"issue":"1","key":"bib33-20250430","doi-asserted-by":"crossref","first-page":"8","DOI":"10.2185\/jrm.2020-036","article-title":"Effects of conservative treatment of 2-week rigorous bed rest on muscle disuse atrophy in osteoporotic vertebral fracture patients","volume":"16","author":"Ikumi","year":"2021","journal-title":"J Rural Med."},{"issue":"12","key":"bib34-20250430","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1007\/s00198-003-1510-4","article-title":"Impact of postural deformities and spinal mobility on quality of life in postmenopausal osteoporosis","volume":"14","author":"Miyakoshi","year":"2003","journal-title":"Osteoporos Int."},{"issue":"8","key":"bib35-20250430","doi-asserted-by":"crossref","first-page":"1362","DOI":"10.1016\/j.spinee.2021.03.014","article-title":"Does spinal sagittal imbalance lead to future vertebral compression fractures in osteoporosis patients?","volume":"21","author":"Lin","year":"2021","journal-title":"Spine J."},{"issue":"1","key":"bib36-20250430","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1007\/s00590-016-1844-1","article-title":"Does spinopelvic alignment affect the union status in thoracolumbar osteoporotic vertebral compression fracture?","volume":"27","author":"Iwata","year":"2017","journal-title":"Eur J Orthop Surg Traumatol."},{"issue":"7","key":"bib37-20250430","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.1007\/s00198-008-0777-x","article-title":"Impact of spinal kyphosis on gastroesophageal reflux disease symptoms in patients with osteoporosis","volume":"20","author":"Miyakoshi","year":"2009","journal-title":"Osteoporos Int."},{"issue":"2","key":"bib38-20250430","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1007\/s00198-021-06136-6","article-title":"The association between hyperkyphosis and fall incidence among community-dwelling older adults","volume":"33","author":"Koel\u00e9","year":"2022","journal-title":"Osteoporos Int."},{"issue":"1","key":"bib39-20250430","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1007\/s00198-017-4253-3","article-title":"Kyphosis and incident falls among community-dwelling older adults","volume":"29","author":"McDaniels-Davidson","year":"2018","journal-title":"Osteoporos Int."},{"issue":"15","key":"bib40-20250430","doi-asserted-by":"crossref","first-page":"1232","DOI":"10.1097\/BRS.0000000000001602","article-title":"Relationship between kyphotic posture and falls in community-dwelling men and women: The Locomotive Syndrome and Health Outcome in Aizu Cohort Study","volume":"41","author":"Tominaga","year":"2016","journal-title":"Spine (Phila Pa 1976)."},{"issue":"1","key":"bib41-20250430","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1007\/s00774-019-01023-x","article-title":"Comparison of once-weekly teriparatide and alendronate against new osteoporotic vertebral fractures at week 12","volume":"38","author":"Ikeda","year":"2020","journal-title":"J Bone Miner Metab."},{"issue":"1","key":"bib42-20250430","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1186\/s12891-017-1509-1","article-title":"Effect of teriparatide (rh-PTH 1-34) versus bisphosphonate on the healing of osteoporotic vertebral compression fracture: A retrospective comparative study","volume":"18","author":"Iwata","year":"2017","journal-title":"BMC Musculoskelet Disord."},{"issue":"1","key":"bib43-20250430","doi-asserted-by":"crossref","first-page":"19","DOI":"10.13004\/kjnt.2019.15.e13","article-title":"Can three months of teriparatide be one of treatment options for osteoporotic vertebral compression fracture patients?","volume":"15","author":"Kang","year":"2019","journal-title":"Korean J Neurotrauma."},{"issue":"5","key":"bib44-20250430","doi-asserted-by":"crossref","first-page":"763","DOI":"10.31616\/asj.2018.0311","article-title":"Effects of weekly teriparatide administration for vertebral stability and bony union in patients with acute osteoporotic vertebral fractures","volume":"13","author":"Kitaguchi","year":"2019","journal-title":"Asian Spine J."},{"issue":"11","key":"bib45-20250430","doi-asserted-by":"crossref","first-page":"2249","DOI":"10.1007\/s00198-019-05125-0","article-title":"Effects of anti-osteoporosis medications on radiological and clinical results after acute osteoporotic spinal fractures: a retrospective analysis of prospectively designed study","volume":"30","author":"Min","year":"2019","journal-title":"Osteoporos Int."},{"issue":"2","key":"bib46-20250430","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1007\/s00198-013-2458-7","article-title":"Preventive effects of conservative treatment with short-term teriparatide on the progression of vertebral body collapse after osteoporotic vertebral compression fracture","volume":"25","author":"Park","year":"2014","journal-title":"Osteoporos Int."},{"key":"bib47-20250430","doi-asserted-by":"crossref","first-page":"100217","DOI":"10.1016\/j.bonr.2019.100217","article-title":"The efficacy of osteoporotic treatment in patients with new spinal vertebral compression fracture pain, ADL, QOL, bone metabolism and fracture-healing - In comparison with weekly teriparatide with bisphosphonate","volume":"11","author":"Shigenobu","year":"2019","journal-title":"Bone Rep."},{"issue":"2","key":"bib48-20250430","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1007\/s00198-015-3243-6","article-title":"Does bisphosphonate-based anti-osteoporosis medication affect osteoporotic spinal fracture healing?","volume":"27","author":"Ha","year":"2016","journal-title":"Osteoporos Int."},{"issue":"1","key":"bib49-20250430","doi-asserted-by":"crossref","first-page":"15","DOI":"10.11005\/jbm.2020.27.1.15","article-title":"Effect of osteoporosis medication on fracture healing: An evidence based review","volume":"27","author":"Shin","year":"2020","journal-title":"J Bone Metab."}],"container-title":["Journal of Bone and Joint Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.2106\/JBJS.22.00116","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T13:45:10Z","timestamp":1787751910000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.2106\/JBJS.22.00116"}},"subtitle":["A Prospective Cohort Study"],"short-title":[],"issued":{"date-parts":[[2022,8,24]]},"references-count":49,"journal-issue":{"issue":"20","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.2106\/jbjs.22.00116","relation":{},"ISSN":["0021-9355","1535-1386"],"issn-type":[{"value":"0021-9355","type":"print"},{"value":"1535-1386","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,8,24]]}}}