{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T21:28:50Z","timestamp":1789680530918,"version":"4.0.1"},"reference-count":26,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"12","license":[{"start":{"date-parts":[[2023,4,26]],"date-time":"2023-04-26T00:00:00Z","timestamp":1682467200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,6,21]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>We evaluated long-term outcomes (radiographic parameters and pulmonary function) at a minimum follow-up of 5 years after use of dual growing rods (DGRs) to treat severe early-onset scoliosis (sEOS).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Among a total of 112 patients who were diagnosed with early-onset scoliosis (EOS) and were treated with DGRs between 2006 and 2015, 52 patients had sEOS, with a major Cobb angle of &gt;80\u00b0. Of these patients, 39 with a minimum follow-up of 5 years had complete radiographic and pulmonary function test results and were included. The Cobb angle of the major curve, T1-S1 height, T1-T12 height, and maximum kyphosis angle in the sagittal plane were measured on radiographs. Pulmonary function test results were collected in all patients before the initial operation (preoperatively), 12 months after the initial operation (postoperatively), and at the last follow-up. The changes in pulmonary function and complications during treatment were analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The mean age of patients before the initial operation was 7.7 \u00b1 1.2 years, and the mean follow-up period was 75.0 \u00b1 14.1 months. The mean number of lengthenings was 4.5 \u00b1 1.3, and the mean interval between lengthenings was 11.2 \u00b1 2.1 months. The Cobb angle improved from 104.5\u00b0 \u00b1 18.2\u00b0 preoperatively to 38.1\u00b0 \u00b1 10.1\u00b0 after the initial surgical procedure (postoperatively) and 21.9\u00b0 \u00b1 8.6\u00b0 at the final follow-up. The T1-S1 height increased from 25.1 \u00b1 4.0 cm preoperatively to 32.4 \u00b1 3.5 cm postoperatively and to 39.5 \u00b1 4.0 cm at the final follow-up. However, no significant difference was detected between the increased pulmonary function parameters at 1 year and those before the operation (p &gt; 0.05), except for residual volume, whereas pulmonary function parameters had significantly increased at the final follow-up (p &lt; 0.05). During the treatment period, 17 complications occurred in 12 patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>DGRs are effective in treating sEOS in the long term. They allow longitudinal growth of the spine, and the correction of the spinal deformity can provide conditions that make improving pulmonary function possible in patients with sEOS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence:<\/jats:title>\n                    <jats:p>\n                      Therapeutic\n                      <jats:underline>Level IV<\/jats:underline>\n                      . See Instructions for Authors for a complete description of levels of evidence.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.2106\/jbjs.22.01088","type":"journal-article","created":{"date-parts":[[2023,4,26]],"date-time":"2023-04-26T14:25:45Z","timestamp":1682519145000},"page":"915-923","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":19,"title":["Long-Term Radiographic and Pulmonary Function Outcomes After Dual Growing-Rod Treatment for Severe Early-Onset Scoliosis"],"prefix":"10.2106","volume":"105","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0258-3698","authenticated-orcid":false,"given":"Yunsheng","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Orthopedic Surgery, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7206-325X","authenticated-orcid":false,"given":"Yong","family":"Hai","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8864-9124","authenticated-orcid":false,"given":"Nan","family":"Kang","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2779-7593","authenticated-orcid":false,"given":"Jincai","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9563-138X","authenticated-orcid":false,"given":"Qingjun","family":"Su","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2128-4594","authenticated-orcid":false,"given":"Yuzeng","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8879-6338","authenticated-orcid":false,"given":"Li","family":"Guan","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8752-9414","authenticated-orcid":false,"given":"Xianglong","family":"Meng","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2023,4,26]]},"reference":[{"issue":"1","key":"bib1-20250430","doi-asserted-by":"crossref","first-page":"S109","DOI":"10.1016\/j.otsr.2014.06.032","article-title":"Early-onset scoliosis: current treatment","volume":"101","author":"Cunin","year":"2015","journal-title":"Orthop Traumatol Surg Res."},{"issue":"1","key":"bib2-20250430","doi-asserted-by":"crossref","DOI":"10.1542\/peds.2015-0709","article-title":"Early-onset scoliosis: a review of history, current 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