{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T14:50:25Z","timestamp":1787755825479,"version":"build-2784847793"},"reference-count":35,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"22","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,11,15]]},"abstract":"<jats:sec>\n                    <jats:title>Update:<\/jats:title>\n                    <jats:p>This article was updated on July 22, 2024, because of a previous error. On page 1757, the Note that had read \u201cThe CORE Study Group includes Todd M. Chapman Jr., MD; Bruce E. Cohen, MD; Patrick M. Connor, MD; Brian M. Curtin, MD; W. Hodges Davis, MD; J. Kent Ellington, MD; James E. Fleischli, MD; Samuel E. Ford, MD; Todd A. Irwin, MD; Carroll P. Jones III, MD; R. Alden Milam IV, MD; Bryan M. Saltzman, MD; P. Bradley P. Segebarth; Shadley C. Schiffern, MD; and Scott B. Shawen, MD.\u201d now reads \u201cThe CORE Study Group includes Todd M. Chapman Jr., MD; Bruce E. Cohen, MD; Patrick M. Connor, MD; Brian M. Curtin, MD; W. Hodges Davis, MD; J. Kent Ellington, MD; James E. Fleischli, MD; Samuel E. Ford, MD; Todd A. Irwin, MD; Carroll P. Jones III, MD; Daniel P. Leas, MD; R. Alden Milam IV, MD; Bryan M. Saltzman, MD; P. Bradley Segebarth, MD; Shadley C. Schiffern, MD; and Scott B. Shawen, MD.\u201d<\/jats:p>\n                    <jats:p>An erratum has been published: J Bone Joint Surg Am. 2024 Sep 4;106(17):e39.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>We hypothesized that an opioid-free (OF), multimodal pain management pathway for thumb carpometacarpal (CMC) joint arthroplasty would not have inferior pain control compared with that of a standard opioid-containing (OC) pathway.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This was a single-center, randomized controlled clinical trial of patients undergoing primary thumb CMC joint arthroplasty. Patients were randomly allocated to either a completely OF analgesic pathway or a standard OC analgesic pathway. Patients in both cohorts received a preoperative brachial plexus block utilizing 30 mL of 0.5% ropivacaine that was administered via ultrasound guidance. The OF group was given a combination of cryotherapy, anti-inflammatory medications, acetaminophen, and gabapentin. The OC group was only given cryotherapy and opioid-containing medication for analgesia. Patient-reported pain was assessed with use of a 0 to 10 numeric rating scale at 24 hours, 2 weeks, and 6 weeks postoperatively. We compared the demographics, opioid-related side effects, patient satisfaction, and Veterans RAND 12-Item Health Survey (VR-12) results between these 2 groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>At 24 hours postoperatively, pain scores in the OF group were statistically noninferior to, and lower than, those in the OC group (median, 2 versus 4; p = 0.008). Pain scores continued to differ significantly at 2 weeks postoperatively (median, 2 versus 4; p = 0.001) before becoming more similar at 6 weeks (p &gt; 0.05). No difference was found between groups with respect to opioid-related side effects, patient satisfaction, or VR-12 results.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>A completely opioid-free perioperative protocol is effective for the treatment of pain following thumb CMC joint arthroplasty in properly selected patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence:<\/jats:title>\n                    <jats:p>\n                      Therapeutic\n                      <jats:underline>Level I<\/jats:underline>\n                      . See Instructions for Authors for a complete description of levels of evidence.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.2106\/jbjs.22.01278","type":"journal-article","created":{"date-parts":[[2023,8,31]],"date-time":"2023-08-31T14:36:11Z","timestamp":1693492571000},"page":"1750-1758","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":10,"title":["Opioid-Free Analgesia Provides Pain Control Following Thumb Carpometacarpal Joint Arthroplasty"],"prefix":"10.2106","volume":"105","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1731-1775","authenticated-orcid":false,"given":"Alexander A.","family":"Hysong","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery, Atrium Health Musculoskeletal Institute, Charlotte, North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7769-4782","authenticated-orcid":false,"given":"Susan 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