{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T07:25:54Z","timestamp":1791617154040,"version":"4.3.4"},"reference-count":54,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"8","license":[{"start":{"date-parts":[[2025,12,9]],"date-time":"2025-12-09T00:00:00Z","timestamp":1765238400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,4,15]]},"abstract":"<jats:p>Talar OsteoPeriostic grafting from the Iliac Crest (TOPIC) for large osteochondral lesions of the medial talar dome was shown to be effective at 2 years of follow-up. In this prospective cohort study, our aim was to evaluate the clinical and radiographic outcomes at 5 years of follow-up. The primary outcome was the Numeric Rating Scale (NRS) score for pain during walking. Secondary outcomes included NRS scores for pain during rest and during stair-climbing as well as scores on the Foot and Ankle Outcome Score (FAOS) subscales, Short Form (SF)-36 Physical Component Summary and Mental Component Summary scores, and the American Orthopaedic Foot &amp; Ankle Society (AOFAS) ankle-hindfoot score. Computed tomography (CT) scans were evaluated. Thirty-seven patients were included. Two patients died and 2 underwent ankle arthrodesis before 5 years and thus were not included in the 5-year statistical analysis of outcomes. The median NRS score for pain during walking improved from 7 (interquartile range [IQR], 5 to 8) preoperatively to 2 (IQR, 1 to 4) at 5 years (p &lt; 0.001), surpassing the minimal clinically important difference. All secondary clinical outcomes improved significantly. All grafts showed incorporation, and 87% of the patients with a CT scan at 5 years demonstrated evidence of cyst formation. Osteoperiosteal autografting using the TOPIC technique is an effective treatment option for large medial osteochondral lesions of the talus, with durable results at 5 years of follow-up.<\/jats:p>\n                  <jats:sec>\n                    <jats:title>Level of Evidence:<\/jats:title>\n                    <jats:p>\n                      Therapeutic\n                      <jats:underline>Level IV<\/jats:underline>\n                      . See Instructions for Authors for a complete description of levels of evidence.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.2106\/jbjs.24.01377","type":"journal-article","created":{"date-parts":[[2025,12,9]],"date-time":"2025-12-09T19:00:26Z","timestamp":1765306826000},"page":"593-599","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":6,"title":["Sustained Improvement in Pain with Talar OsteoPeriostic Grafting from the Iliac Crest (TOPIC) for Medial Osteochondral Lesions of the Talus"],"prefix":"10.2106","volume":"108","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8345-1648","authenticated-orcid":false,"given":"Julian J.","family":"Hollander","sequence":"first","affiliation":[{"name":"Department of Orthopedic Surgery and Sports Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands"},{"name":"Amsterdam Movement Sciences, Programs Sports and Musculoskeletal Health, 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