{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T14:43:40Z","timestamp":1787755420448,"version":"build-2784847793"},"reference-count":28,"publisher":"Ovid Technologies (Wolters Kluwer Health)","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"\n Background:<\/jats:title>\n The aim of this study was to ascertain whether mild cartilage damage of the lateral condyle of the femur influences the mid-term clinical outcomes of medial unicompartmental knee arthroplasty (mUKA) and exacerbates the progression of osteoarthritis in the lateral compartment.<\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n Patients with normal cartilage or mild cartilage damage of the lateral femoral condyle (Outerbridge grade, \u2264II) who underwent mUKA between March 2016 and December 2020 were retrospectively divided into 4 groups: a normal cartilage group and a cartilage damage group that was subdivided on the basis of the damage location (weight-bearing area, posterior weight-bearing area, and medial side of the lateral condyle). Patients with postoperative overcorrection of limb alignment or preoperative lateral meniscal extrusion were excluded. Outcomes that were compared among the groups included the hip-knee-ankle angle (HKA), lateral compartment Kellgren-Lawrence (K-L) grade, Oxford Knee Score (OKS), Forgotten Joint Score (FJS), Kujala score, patient satisfaction, and complications.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n The study included 203 knees in 177 patients (136 female patients; 177 East Asian; mean age, 68.3 \u00b1 7.1 years) with a mean follow-up of 70.8 months (range, 48 to 106 months). The postoperative OKS, FJS, and Kujala score showed no significant differences among the groups. Mid-term full-length standing radiographs of the lower limbs were obtained for 99 of the 203 knees, with a mean follow-up of 54.1 months (range, 49 to 104 months). Of the 99 knees, 26 (26.3%) showed an increase of 1 K-L grade in the lateral compartment and 73 (73.7%) remained unchanged. Three knees (1.5%) from the normal group experienced complications, including 1 periprosthetic fracture, 1 bearing dislocation, and 1 bearing rotation, but none required conversion to TKA.<\/jats:p>\n <\/jats:sec>\n \n Conclusions:<\/jats:title>\n In patients in whom postoperative alignment is not overcorrected and preoperative lateral meniscal function is intact, mild cartilage damage (Outerbridge grade I or II) of the lateral femoral condyle does not impact the mid-term clinical outcomes of mUKA and does not exacerbate the progression of osteoarthritis in the lateral compartment.<\/jats:p>\n <\/jats:sec>\n \n Level of Evidence:<\/jats:title>\n \n Prognostic\n Level III<\/jats:underline>\n . See Instructions for Authors for a complete description of levels of evidence.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.2106\/jbjs.25.01031","type":"journal-article","created":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T19:00:31Z","timestamp":1772132431000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Mild Lateral Femoral Condyle Cartilage Damage Does Not Affect the Outcomes of Medial Unicompartmental Knee Arthroplasty"],"prefix":"10.2106","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-5955-537X","authenticated-orcid":false,"given":"Mincong","family":"Du","sequence":"first","affiliation":[{"name":"Beijing Jishuitan Hospital, Capital Medical University, Beijing, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4272-1311","authenticated-orcid":false,"given":"Zheng","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, Xuanwu Hospital, Capital Medical University, Beijing, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2469-4030","authenticated-orcid":false,"given":"Xufeng","family":"Jiao","sequence":"additional","affiliation":[{"name":"China-Japan Friendship Hospital, Institute of Clinical Medical Sciences, Chinese Academy of Medical Sciences\/Peking Union Medical College, Beijing, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4234-2634","authenticated-orcid":false,"given":"Shuai","family":"An","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, Xuanwu Hospital, Capital Medical University, Beijing, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1210-3758","authenticated-orcid":false,"given":"Xiaomei","family":"Yao","sequence":"additional","affiliation":[{"name":"Department of Health Research Methods, Evidence & Impact, McMaster University, Hamilton, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-7948-993X","authenticated-orcid":false,"given":"Jiang","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, Xuanwu Hospital, Capital Medical University, Beijing, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-3474-5705","authenticated-orcid":false,"given":"Guobin","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, The First Hospital of Hebei Medical University, Shijiazhuang, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8456-9522","authenticated-orcid":false,"given":"Guanglei","family":"Cao","sequence":"additional","affiliation":[{"name":"Beijing Jishuitan Hospital, Capital Medical University, Beijing, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3336-0785","authenticated-orcid":false,"given":"Ye","family":"Huang","sequence":"additional","affiliation":[{"name":"Beijing Jishuitan Hospital, Capital Medical University, Beijing, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,2,26]]},"reference":[{"issue":"9","key":"bib1-20260630","doi-asserted-by":"crossref","first-page":"979","DOI":"10.3928\/0147-7447-20000901-29","article-title":"Unicompartmental knee replacement: now or never?","volume":"23","author":"Murray","year":"2000","journal-title":"Orthopedics."},{"issue":"12","key":"bib2-20260630","doi-asserted-by":"crossref","first-page":"2341","DOI":"10.1007\/s00264-015-2809-4","article-title":"Unicompartmental knee arthroplasty is effective: ten year results","volume":"39","author":"Vasso","year":"2015","journal-title":"Int Orthop."},{"key":"bib3-20260630","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.knee.2021.01.009","article-title":"Forgotten Joint Score: Comparison between total and unicondylar knee arthroplasty","volume":"29","author":"Gill","year":"2021","journal-title":"Knee."},{"issue":"7","key":"bib4-20260630","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1016\/j.arth.2023.01.024","article-title":"15-Year Follow-Up of Mobile Bearing Medial Unicompartmental Knee Arthroplasty","volume":"38","author":"Crawford","year":"2023","journal-title":"J Arthroplasty."},{"issue":"23","key":"bib5-20260630","article-title":"The effects of varus degree on the early metabolic changes of the lateral compartment cartilage in knees with medial unicompartmental osteoarthritis","volume":"38","author":"Wan","year":"2018","journal-title":"Zhonghua Guke Zazhi."},{"issue":"1","key":"bib6-20260630","doi-asserted-by":"crossref","first-page":"145","DOI":"10.2106\/00004623-198971010-00023","article-title":"Unicondylar knee arthroplasty","volume":"71","author":"Kozinn","year":"1989","journal-title":"J Bone Joint Surg Am."},{"issue":"12","key":"bib8-20260630","doi-asserted-by":"crossref","first-page":"3949","DOI":"10.1007\/s00402-021-04254-8","article-title":"Slight cartilage damage in weight-bearing area of lateral femoral condyle do not compromise short-term outcomes of medial unicompartmental knee arthroplasty","volume":"142","author":"Jiao","year":"2022","journal-title":"Arch Orthop Trauma Surg."},{"issue":"9","key":"bib9-20260630","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/j.arth.2013.01.005","article-title":"Medial mobile bearing unicompartmental knee arthroplasty: early survivorship and analysis of failures in 1000 consecutive cases","volume":"28","author":"Bergeson","year":"2013","journal-title":"J Arthroplasty."},{"issue":"5","key":"bib10-20260630","doi-asserted-by":"crossref","first-page":"469","DOI":"10.3109\/17453679808997780","article-title":"Revision of unicompartmental knee arthroplasty: outcome in 1,135 cases from the Swedish Knee Arthroplasty study","volume":"69","author":"Lewold","year":"1998","journal-title":"Acta Orthop Scand."},{"issue":"2","key":"bib11-20260630","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1302\/0301-620X.93B2.25767","article-title":"Minimally invasive Oxford phase 3 unicompartmental knee replacement: results of 1000 cases","volume":"93","author":"Pandit","year":"2011","journal-title":"J Bone Joint Surg Br."},{"issue":"4","key":"bib12-20260630","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/j.jclinepi.2007.11.008","article-title":"The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies","volume":"61","author":"von Elm","year":"2008","journal-title":"J Clin Epidemiol."},{"issue":"5","key":"bib13-20260630","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1302\/2633-1462.25.BJO-2021-0028.R1","article-title":"Arithmetic hip-knee-ankle angle (aHKA): An algorithm for estimating constitutional lower limb alignment in the arthritic patient population","volume":"2","author":"Griffiths-Jones","year":"2021","journal-title":"Bone Jt Open."},{"issue":"12","key":"bib14-20260630","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.2106\/JBJS.21.00801","article-title":"Pre-Arthritic\/Kinematic Alignment in Fixed-Bearing Medial Unicompartmental Knee Arthroplasty Results in Return to Activity at Mean 10-Year Follow-up","volume":"104","author":"Plancher","year":"2022","journal-title":"J Bone Joint Surg Am."},{"issue":"2","key":"bib15-20260630","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1002\/mrm.21146","article-title":"Impact of coil design on the contrast-to-noise ratio, precision, and consistency of quantitative cartilage morphometry at 3 Tesla: a pilot study for the osteoarthritis initiative","volume":"57","author":"Eckstein","year":"2007","journal-title":"Magn Reson Med."},{"issue":"4","key":"bib16-20260630","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1302\/0301-620X.68B4.3733839","article-title":"Stress radiography in degenerative arthritis of the knee","volume":"68","author":"Gibson","year":"1986","journal-title":"J Bone Joint Surg Br."},{"issue":"9","key":"bib17-20260630","doi-asserted-by":"crossref","first-page":"3236","DOI":"10.1007\/s00167-021-06729-y","article-title":"Lateral osteoarthritis progression is associated with a postoperative residual tibiofemoral subluxation in Oxford UKA","volume":"30","author":"Kamenaga","year":"2022","journal-title":"Knee Surg Sports Traumatol Arthrosc."},{"issue":"3","key":"bib18-20260630","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.knee.2011.03.001","article-title":"The effect of gender on outcome of unicompartmental knee arthroplasty","volume":"19","author":"Lustig","year":"2012","journal-title":"Knee."},{"issue":"3","key":"bib19-20260630","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1302\/0301-620X.92B3.23561","article-title":"The implications of damage to the lateral femoral condyle on medial unicompartmental knee replacement","volume":"92","author":"Kendrick","year":"2010","journal-title":"J Bone Joint Surg Br."},{"issue":"1","key":"bib20-20260630","doi-asserted-by":"crossref","first-page":"46","DOI":"10.5792\/ksrr.2016.28.1.46","article-title":"Analysis and treatment of complications after unicompartmental knee arthroplasty","volume":"28","author":"Kim","year":"2016","journal-title":"Knee Surg Relat Res."},{"issue":"8","key":"bib21-20260630","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1016\/j.otsr.2009.10.006","article-title":"Fixed versus mobile bearing unicompartmental knee replacement: a meta-analysis","volume":"95","author":"Smith","year":"2009","journal-title":"Orthop Traumatol Surg Res."},{"issue":"5","key":"bib22-20260630","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.jisako.2022.06.001","article-title":"Disease progression, aseptic loosening and bearing dislocations are the main revision indications after lateral unicompartmental knee arthroplasty: a systematic review","volume":"7","author":"Tay","year":"2022","journal-title":"J ISAKOS."},{"issue":"1","key":"bib23-20260630","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1186\/s43019-024-00217-6","article-title":"Coronal plane alignment of the knee (CPAK) classification and its impact on medial unicompartmental knee arthroplasty: exposing a unexpected external shift of limb mechanical axis in case of prearthritic constitutional valgus alignment: a retrospective radiographic study","volume":"36","author":"Digennaro","year":"2024","journal-title":"Knee Surg Relat Res."},{"issue":"21","key":"bib24-20260630","doi-asserted-by":"crossref","first-page":"2563","DOI":"10.4103\/0366-6999.217076","article-title":"Effects of Lower Limb Alignment and Tibial Component Inclination on the Biomechanics of Lateral Compartment in Unicompartmental Knee Arthroplasty","volume":"130","author":"Wen","year":"2017","journal-title":"Chin Med J (Engl)."},{"issue":"2","key":"bib25-20260630","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1002\/art.37726","article-title":"Valgus malalignment is a risk factor for lateral knee osteoarthritis incidence and progression: findings from the Multicenter Osteoarthritis Study and the Osteoarthritis Initiative","volume":"65","author":"Felson","year":"2013","journal-title":"Arthritis Rheum."},{"issue":"3","key":"bib26-20260630","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/j.joca.2012.11.015","article-title":"Tibial coverage, meniscus position, size and damage in knees discordant for joint space narrowing - data from the Osteoarthritis Initiative","volume":"21","author":"Bloecker","year":"2013","journal-title":"Osteoarthritis Cartilage."},{"issue":"6","key":"bib27-20260630","first-page":"618","article-title":"The Influence of Obesity on Unicompartmental Knee Arthroplasty Outcomes: A Systematic Review And Meta-Analysis","volume":"9","author":"Ng","year":"2021","journal-title":"Arch Bone Jt Surg."},{"issue":"10","key":"bib28-20260630","doi-asserted-by":"crossref","first-page":"3467","DOI":"10.1007\/s00167-020-06297-7","article-title":"The effect of obesity on revision rate in unicompartmental knee arthroplasty: a systematic review and meta-analysis","volume":"29","author":"Musbahi","year":"2021","journal-title":"Knee Surg Sports Traumatol Arthrosc."},{"issue":"2","key":"bib29-20260630","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/S0749-8063(05)80366-4","article-title":"Scoring of patellofemoral disorders","volume":"9","author":"Kujala","year":"1993","journal-title":"Arthroscopy."}],"container-title":["Journal of Bone and Joint Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.2106\/JBJS.25.01031","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T13:42:33Z","timestamp":1787751753000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.2106\/JBJS.25.01031"}},"subtitle":["A Mean 6-Year Follow-up Study"],"short-title":[],"issued":{"date-parts":[[2026,2,26]]},"references-count":28,"URL":"https:\/\/doi.org\/10.2106\/jbjs.25.01031","relation":{},"ISSN":["0021-9355","1535-1386"],"issn-type":[{"value":"0021-9355","type":"print"},{"value":"1535-1386","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,26]]}}}