{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T14:46:02Z","timestamp":1787755562957,"version":"build-2784847793"},"reference-count":42,"publisher":"Ovid Technologies (Wolters Kluwer Health)","license":[{"start":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T00:00:00Z","timestamp":1771459200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Periprosthetic femoral fractures (PFFs) are an increasingly common indication for revision total hip arthroplasty (THA). While patient-related risk factors are well documented, the influence of femoral stem design on PFF risk remains poorly characterized. In this study using nationwide data, we assessed the association between stem design and PFF risk.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We analyzed 182,118 primary THAs (performed from 2015 to 2023) from the Swiss National Joint Registry (SIRIS). Cementless stems were categorized according to the Kheir classification, and cemented stems were categorized as double-tapered polished, triple-tapered polished, composite-beam, or custom. A multivariable Cox regression model, including variables such as age, sex, American Society of Anesthesiologists (ASA) class, body mass index (BMI), surgical indication, prior ipsilateral hip surgery, stem design, collar, dual-mobility cup, bearing, and head size, was analyzed. Hazard ratios (HRs) with 95% confidence intervals (CIs) are reported.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Among 182,118 THAs (mean patient age, 68.9 \u00b1 11.5 years; female sex in 53.1% of cases), 1,226 (0.7%) were complicated by PFF. The cumulative incidence of PFF reached 0.7% at 5 years and 1.3% at 10 years. Higher PFF risk was associated with an age of 75 to 84 years (HR = 1.68 [95% CI = 1.44 to 1.96]) and \u226585 years (HR = 1.86 [95% CI = 1.47 to 2.35]), ASA class of 3 to 5 (females, HR = 1.70; males, HR = 1.73), BMI of &lt;18.5 kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      (HR = 1.61) or \u226540 kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      (HR = 1.64), prior ipsilateral hip surgery (HR = 1.32), and use of a dual-mobility cup (HR = 1.56). Elective procedures (HR = 0.36) and collared stems (HR = 0.26) were associated with a lower risk. Compared with cementless type-3 stems, cementless type-7 (anatomic) stems showed a higher risk of PFF (HR = 1.88), whereas cementless type-1B (HR = 0.62) and composite-beam cemented stems (HR = 0.45) were protective.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>In this large nationwide registry study, femoral stem design independently influenced PFF risk after primary THA. Cementless anatomic stems increased the risk, whereas composite-beam cemented stems and the presence of a collar conferred a protective effect. These findings support personalized implant selection, particularly for older patients or those with frailty.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence:<\/jats:title>\n                    <jats:p>\n                      Prognostic\n                      <jats:underline>Level III<\/jats:underline>\n                      . See Instructions for Authors for a complete description of levels of evidence.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.2106\/jbjs.25.01203","type":"journal-article","created":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T19:00:45Z","timestamp":1771527645000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Impact of Stem Design on Periprosthetic Femoral Fracture Risk"],"prefix":"10.2106","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4117-4651","authenticated-orcid":false,"given":"P.A.","family":"Bouch\u00e9","sequence":"first","affiliation":[{"name":"Division of Orthopedic Surgery and Traumatology, Geneva University Hospitals, Geneva, Switzerland"},{"name":"Faculty of Medicine, University of Paris Cit\u00e9, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"L\u00fcbbeke","sequence":"additional","affiliation":[{"name":"Division of Orthopedic Surgery and Traumatology, Geneva University Hospitals, Geneva, Switzerland"},{"name":"Faculty of Medicine, University of Geneva, Geneva, Switzerland"},{"name":"Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8623-9909","authenticated-orcid":false,"given":"C.","family":"Brand","sequence":"additional","affiliation":[{"name":"Swiss National Joint Registry (SIRIS), Bern, Switzerland"},{"name":"Institute of Social and Preventive Medicine, Bern, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9231-0353","authenticated-orcid":false,"given":"A.I.","family":"Gonzalez","sequence":"additional","affiliation":[{"name":"Division of Orthopedic Surgery and Traumatology, Geneva University Hospitals, Geneva, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0697-946X","authenticated-orcid":false,"given":"M.","family":"Beck","sequence":"additional","affiliation":[{"name":"Swiss National Joint Registry (SIRIS), Bern, Switzerland"},{"name":"Orthopaedic Clinic Lucerne, Lucerne, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Hannouche","sequence":"additional","affiliation":[{"name":"Division of Orthopedic Surgery and Traumatology, Geneva University Hospitals, Geneva, Switzerland"},{"name":"Faculty of Medicine, University of Geneva, Geneva, 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A regional registry-based study on 12,010 total hip arthroplasty implants according to stem length and neck modularity","volume":"26","author":"Di Martino","year":"2025","journal-title":"J Orthop Traumatol."},{"issue":"1","key":"bib25-20260415","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1302\/0301-620X.99B1.BJJ-2016-0220.R1","article-title":"Periprosthetic femoral fractures and trying to avoid them: what is the contribution of femoral component design to the increased risk of periprosthetic femoral fracture?","volume":"99-B","author":"Carli","year":"2017","journal-title":"Bone Joint J."},{"issue":"4","key":"bib26-20260415","doi-asserted-by":"crossref","first-page":"1062","DOI":"10.1016\/j.arth.2024.10.028","article-title":"Does Femoral Stem Design Influence Periprosthetic Fracture Incidence and Morphology in Total Hip Arthroplasty?","volume":"40","author":"Cochrane","year":"2025","journal-title":"J Arthroplasty."},{"issue":"8S1","key":"bib27-20260415","doi-asserted-by":"crossref","first-page":"S322","DOI":"10.1016\/j.arth.2025.02.036","article-title":"Does Stem Design Affect the Incidence of Periprosthetic Femoral Fractures in Arthroplasty for Femoral Neck Fractures? 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