{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T14:35:35Z","timestamp":1787754935955,"version":"build-2784847793"},"reference-count":13,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JBJS Case Connector"],"published-print":{"date-parts":[[2016,8,24]]},"abstract":"<jats:sec>\n                    <jats:title>Case:<\/jats:title>\n                    <jats:p>\n                      We present the case of a patient who had worsening pain following intra-articular knee corticosteroid injection and who subsequently underwent arthroscopic partial meniscectomy with positive intraoperative cultures for\n                      <jats:italic toggle=\"yes\">Staphylococcus lugdunensis<\/jats:italic>\n                      . He was treated with multiple irrigation and debridements, and subsequent work-up yielded a diagnosis of immunoglobulin G (IgG) deficiency. We believe that it is critical to maintain a high index of suspicion for underlying immune deficiency when faced with atypical presentations of infections or atypical bacteria in otherwise healthy patients.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Knee arthroscopy for the treatment of meniscal tears is one of the most common procedures performed by orthopaedic surgeons in the United States. Patients with an antibody deficiency may have a limited or reduced immune response when presented with a pathogen foreign to the body. This may place the patient at an increased risk of infection and should be addressed through referral to the appropriate subspecialists when recurrent or atypical infection presents to the orthopaedic surgeon.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2106\/jbjs.cc.15.00254","type":"journal-article","created":{"date-parts":[[2016,8,24]],"date-time":"2016-08-24T22:58:44Z","timestamp":1472079524000},"page":"e69","source":"Crossref","is-referenced-by-count":1,"title":["Immunoglobulin G Deficiency-Associated Septic Arthritis Identified Following Corticosteroid Injection and Knee Arthroscopy"],"prefix":"10.2106","volume":"6","author":[{"given":"Patrick S.","family":"Buckley","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery, Rothman Institute at Thomas Jefferson University, Philadelphia, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justin","family":"Kane","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Rothman Institute at Thomas Jefferson University, Philadelphia, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael G.","family":"Ciccotti","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Rothman Institute at Thomas Jefferson University, Philadelphia, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"issue":"3","key":"bib1-20230712","doi-asserted-by":"crossref","first-page":"660","DOI":"10.2106\/00004623-200603000-00027","article-title":"American Board of Orthopaedic Surgery practice of the orthopaedic surgeon: part-II, certification examination case mix","volume":"88","author":"Garrett","year":"2006","journal-title":"J Bone Joint Surg Am."},{"issue":"10","key":"bib2-20230712","doi-asserted-by":"crossref","first-page":"2333","DOI":"10.1177\/0363546513495641","article-title":"Trends in meniscus repair and meniscectomy in the United States, 2005-2011","volume":"41","author":"Abrams","year":"2013","journal-title":"Am J Sports Med."},{"issue":"6","key":"bib3-20230712","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1016\/S0749-8063(97)90000-1","article-title":"Fifteen-year follow-up of arthroscopic partial meniscectomy","volume":"13","author":"Burks","year":"1997","journal-title":"Arthroscopy."},{"issue":"2","key":"bib4-20230712","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1177\/0363546513510677","article-title":"Complications after arthroscopic knee surgery","volume":"42","author":"Salzler","year":"2014","journal-title":"Am J Sports Med."},{"issue":"3","key":"bib5-20230712","first-page":"168","article-title":"Septic arthritis","volume":"28","author":"Perry","year":"1999","journal-title":"Am J Orthop (Belle Mead NJ)."},{"issue":"3","key":"bib6-20230712","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1007\/s100670050098","article-title":"Perceived risks of joint infection following intra-articular corticosteroid injections: a survey of rheumatologists","volume":"18","author":"Pal","year":"1999","journal-title":"Clin Rheumatol."},{"issue":"10","key":"bib7-20230712","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1586\/eri.11.110","article-title":"Staphylococcus lugdunensis: the coagulase-negative Staphylococcus you don\u2019t want to ignore","volume":"9","author":"Babu","year":"2011","journal-title":"Expert Rev Anti Infect Ther."},{"issue":"3","key":"bib8-20230712","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1128\/CMR.00001-09","article-title":"Pathogenesis, diagnosis, and management of primary antibody deficiencies and infections","volume":"22","author":"Fried","year":"2009","journal-title":"Clin Microbiol Rev."},{"issue":"5","key":"bib9-20230712","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1007\/s11882-002-0067-1","article-title":"Immunoglobulin G subclass deficiency: fact or fancy?","volume":"2","author":"Buckley","year":"2002","journal-title":"Curr Allergy Asthma Rep."},{"issue":"1","key":"bib10-20230712","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/0090-1229(89)90203-1","article-title":"Serum IgG subclass levels in patients with primary immunodeficiency syndromes or abnormal susceptibility to infections","volume":"51","author":"Aucouturier","year":"1989","journal-title":"Clin Immunol Immunopathol."},{"issue":"2","key":"bib11-20230712","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1053\/j.jfas.2012.10.012","article-title":"Subtalar joint septic arthritis in a patient with hypogammaglobulinemia","volume":"52","author":"Wynes","year":"2013","journal-title":"J Foot Ankle Surg."},{"issue":"4","key":"bib12-20230712","doi-asserted-by":"crossref","first-page":"425","DOI":"10.2169\/internalmedicine.51.6058","article-title":"Hypogammaglobulinemic patient with polyarthritis mimicking rheumatoid arthritis finally diagnosed as septic arthritis caused by Mycoplasma hominis","volume":"51","author":"Sato","year":"2012","journal-title":"Intern Med."},{"issue":"2","key":"bib13-20230712","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1093\/clinids\/24.2.222","article-title":"Mycoplasma felis septic arthritis in a patient with hypogammaglobulinemia","volume":"24","author":"Bonilla","year":"1997","journal-title":"Clin Infect Dis."}],"container-title":["JBJS Case Connector"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/01709767-201606030-00018","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T13:35:11Z","timestamp":1787751311000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/01709767-201606030-00018"}},"subtitle":["A Case Report"],"short-title":[],"issued":{"date-parts":[[2016,8,24]]},"references-count":13,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2016]]}},"URL":"https:\/\/doi.org\/10.2106\/jbjs.cc.15.00254","relation":{},"ISSN":["2160-3251"],"issn-type":[{"value":"2160-3251","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,8,24]]}}}