{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T14:43:27Z","timestamp":1787755407795,"version":"build-2784847793"},"reference-count":18,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JBJS Case Connector"],"abstract":"<jats:sec>\n                    <jats:title>Case:<\/jats:title>\n                    <jats:p>A 19-year-old woman presented with a 3-month history of an enlarging lesion on the proximal aspect of the femur. After imaging studies and a biopsy had been performed, the mass was determined to represent heterotopic ossification (HO). The only known risk factor was a history of concussion. The mass was resected and, as of the 12-month follow-up, had not recurred.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>HO is a potentially serious complication of ossification in soft tissues that can develop secondary to several disease states; it commonly occurs following traumatic brain injury. To our knowledge, this is the only case report that describes HO associated with a concussion and no other risk factors.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2106\/jbjs.cc.17.00158","type":"journal-article","created":{"date-parts":[[2018,5,9]],"date-time":"2018-05-09T21:59:47Z","timestamp":1525903187000},"page":"e26-e26","source":"Crossref","is-referenced-by-count":1,"title":["Heterotopic Ossification Formation Following a Simple Concussion"],"prefix":"10.2106","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8792-4155","authenticated-orcid":false,"given":"Patrick K.","family":"O\u2019Callaghan","sequence":"first","affiliation":[{"name":"Departments of Orthopaedics (P.K.O\u2019C. and Z.W.), Radiology (R.C.), and Pathology and Laboratory Medicine (E.B.), Medical University of South Carolina (E.C.), Charleston, South Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elliott","family":"Carter","sequence":"additional","affiliation":[{"name":"Departments of Orthopaedics (P.K.O\u2019C. and Z.W.), Radiology (R.C.), and Pathology and Laboratory Medicine (E.B.), Medical University of South Carolina (E.C.), Charleston, South Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zeke","family":"Walton","sequence":"additional","affiliation":[{"name":"Departments of Orthopaedics (P.K.O\u2019C. and Z.W.), Radiology (R.C.), and Pathology and Laboratory Medicine (E.B.), Medical University of South Carolina (E.C.), Charleston, South Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Russell","family":"Chapin","sequence":"additional","affiliation":[{"name":"Departments of Orthopaedics (P.K.O\u2019C. and Z.W.), Radiology (R.C.), and Pathology and Laboratory Medicine (E.B.), Medical University of South Carolina (E.C.), Charleston, South Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evelyn","family":"Bruner","sequence":"additional","affiliation":[{"name":"Departments of Orthopaedics (P.K.O\u2019C. and Z.W.), Radiology (R.C.), and Pathology and Laboratory Medicine (E.B.), Medical University of South Carolina (E.C.), Charleston, South Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2018,6]]},"reference":[{"issue":"6","key":"bib1-20230712","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1007\/s11916-016-0573-9","article-title":"The pathophysiology of concussion","volume":"20","author":"Choe","year":"2016","journal-title":"Curr Pain Headache Rep."},{"issue":"5","key":"bib2-20230712","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1136\/bjsports-2013-092313","article-title":"Consensus statement on concussion in sport: the 4th International Conference on Concussion in Sport held in Zurich, November 2012","volume":"47","author":"McCrory","year":"2013","journal-title":"Br J Sports Med."},{"issue":"4","key":"bib3-20230712","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/j.jamcollsurg.2010.05.020","article-title":"Second impact syndrome: concussion and second injury brain complications","volume":"211","author":"Wetjen","year":"2010","journal-title":"J Am Coll Surg."},{"issue":"11","key":"bib4-20230712","doi-asserted-by":"crossref","first-page":"689","DOI":"10.5435\/00124635-200911000-00003","article-title":"Heterotopic ossification following traumatic brain injury and spinal cord injury","volume":"17","author":"Cipriano","year":"2009","journal-title":"J Am Acad Orthop Surg."},{"key":"bib5-20230712","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1097\/00003086-199102000-00003","article-title":"A clinical perspective on common forms of acquired heterotopic ossification","volume":"263","author":"Garland","year":"1991","journal-title":"Clin Orthop Relat Res."},{"key":"bib6-20230712","first-page":"113","article-title":"Funnybones: a review of the problem of heterotopic bone formation","volume":"8","author":"Bayley","year":"1979","journal-title":"Orthop Rev."},{"issue":"2","key":"bib7-20230712","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1302\/0301-620X.74B2.1544955","article-title":"Heterotopic ossification after spinal cord injury. 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