{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T14:42:37Z","timestamp":1787755357958,"version":"build-2784847793"},"reference-count":16,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JBJS Case Connector"],"abstract":"\n Case:<\/jats:title>\n We report the case of a 13-year-old boy with Duchenne muscular dystrophy (DMD) who sustained bilateral femoral neck fractures associated with glucocorticoid-induced osteoporosis. Denosumab therapy for 18 months markedly improved the lumbar bone mineral density and the bone turnover markers. No fractures or complications were recorded during the treatment period.<\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n To the best of our knowledge, this is the first description of denosumab treatment for glucocorticoid-induced osteoporosis in a patient with DMD. The drug merits additional testing as an effective therapy for osteoporosis in patients with DMD.<\/jats:p>\n <\/jats:sec>","DOI":"10.2106\/jbjs.cc.17.00190","type":"journal-article","created":{"date-parts":[[2018,4,11]],"date-time":"2018-04-11T06:37:05Z","timestamp":1523428625000},"page":"e22-e22","source":"Crossref","is-referenced-by-count":21,"title":["Efficacy of Denosumab for Glucocorticoid-Induced Osteoporosis in an Adolescent Patient with Duchenne Muscular Dystrophy"],"prefix":"10.2106","volume":"8","author":[{"given":"Daiki","family":"Kumaki","sequence":"first","affiliation":[{"name":"Departments of Orthopaedic Surgery (D.K., Y.N., T.S., and H.K.) and Medical Genetics (T.K.) and Third Department of Medicine (A.N.), Shinshu University School of Medicine, Matsumoto, 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Matsumoto, Japan"},{"name":"Center for Medical Genetics, Shinshu University Hospital, Matsumoto, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akinori","family":"Nakamura","sequence":"additional","affiliation":[{"name":"Departments of Orthopaedic Surgery (D.K., Y.N., T.S., and H.K.) and Medical Genetics (T.K.) and Third Department of Medicine (A.N.), Shinshu University School of Medicine, Matsumoto, Japan"},{"name":"Department of Neurology, Matsumoto Medical Center, National Hospital Organization, Matsumoto, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinichi","family":"Hirabayashi","sequence":"additional","affiliation":[{"name":"Departments of Orthopaedic Surgery (N.S.) and Child Neurology (S.H.), Nagano Prefectural Children\u2019s Hospital, Azumino, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takako","family":"Suzuki","sequence":"additional","affiliation":[{"name":"Departments of Orthopaedic Surgery 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