{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T14:42:53Z","timestamp":1787755373856,"version":"build-2784847793"},"reference-count":21,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JBJS Case Connector"],"abstract":"<jats:sec>\n                    <jats:title>Case:<\/jats:title>\n                    <jats:p>We review the case of a 44-year-old man with Camurati-Engelmann disease, who presented with chronic right hip pain that did not improve following intra-articular hip injections. He was functionally debilitated because of the worsening pain. Routine radiographs demonstrated severe right hip osteoarthritis and severe diaphyseal sclerosis of the femur. To address the narrowed medullary cavity, appropriate reaming of the diaphysis and broaching to fill the metaphysis were performed. The patient underwent an uncemented total hip arthroplasty that resulted in an excellent recovery with no complications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Uncemented total hip arthroplasty serves as a good option for patients with hip osteoarthritis secondary to Camurati-Engelmann disease. Anticipation of potential operative challenges is the key to avoiding complications and achieving an optimal, durable outcome.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2106\/jbjs.cc.17.00286","type":"journal-article","created":{"date-parts":[[2018,6,26]],"date-time":"2018-06-26T18:58:16Z","timestamp":1530039496000},"page":"e45-e45","source":"Crossref","is-referenced-by-count":3,"title":["Total Hip Arthroplasty in a Patient with Camurati-Engelmann Disease"],"prefix":"10.2106","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8077-4270","authenticated-orcid":false,"given":"David H.","family":"Ge","sequence":"first","affiliation":[{"name":"Division of Adult Reconstruction, Department of Orthopedic Surgery, NYU Langone Orthopedic Hospital, New York, NY"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0107-5771","authenticated-orcid":false,"given":"Stephen","family":"Yu","sequence":"additional","affiliation":[{"name":"Division of Adult Reconstruction, Department of Orthopedic Surgery, NYU Langone Orthopedic Hospital, New York, NY"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1190-4764","authenticated-orcid":false,"given":"Jacob D.","family":"Ziegler","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Mayo Clinic Health System, Mankato, Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0681-7014","authenticated-orcid":false,"given":"Ran","family":"Schwarzkopf","sequence":"additional","affiliation":[{"name":"Division of Adult Reconstruction, Department of Orthopedic Surgery, NYU Langone Orthopedic Hospital, New York, NY"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2018,6]]},"reference":[{"issue":"3","key":"bib1-20230712","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1302\/0301-620X.78B3.0780488","article-title":"Engelmann\u2019s disease: a 45-year follow-up","volume":"78","author":"Grey","year":"1996","journal-title":"J Bone Joint Surg Br."},{"issue":"2","key":"bib2-20230712","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1542\/peds.75.2.321","article-title":"Progressive diaphyseal dysplasia: evaluation of corticosteroid therapy","volume":"75","author":"Naveh","year":"1985","journal-title":"Pediatrics."},{"key":"bib3-20230712","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1302\/0301-620X.43B2.273","article-title":"Engelmann\u2019s disease: report of a case with a review of the literature","volume":"43-B","author":"Lennon","year":"1961","journal-title":"J Bone Joint Surg Br."},{"issue":"1","key":"bib4-20230712","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1136\/jmg.2005.033522","article-title":"Camurati-Engelmann disease: review of the clinical, radiological, and molecular data of 24 families and implications for diagnosis and treatment","volume":"43","author":"Janssens","year":"2006","journal-title":"J Med Genet."},{"issue":"1","key":"bib5-20230712","doi-asserted-by":"crossref","first-page":"109","DOI":"10.4055\/cios.2017.9.1.109","article-title":"Orthopedic manifestations of type I Camurati-Engelmann disease","volume":"9","author":"Yuldashev","year":"2017","journal-title":"Clin Orthop Surg."},{"issue":"9","key":"bib6-20230712","doi-asserted-by":"crossref","first-page":"7718","DOI":"10.1074\/jbc.M208857200","article-title":"Transforming growth factor-beta 1 mutations in Camurati-Engelmann disease lead to increased signaling by altering either activation or secretion of the mutant protein","volume":"278","author":"Janssens","year":"2003","journal-title":"J Biol Chem."},{"issue":"15","key":"bib7-20230712","doi-asserted-by":"crossref","first-page":"11469","DOI":"10.1074\/jbc.C000859200","article-title":"Domain-specific mutations of a transforming growth factor (TGF)-beta 1 latency-associated peptide cause Camurati-Engelmann disease because of the formation of a constitutively active form of TGF-beta 1","volume":"276","author":"Saito","year":"2001","journal-title":"J Biol Chem."},{"issue":"6","key":"bib8-20230712","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1210\/er.2004-0001","article-title":"Transforming growth factor-beta1 to the bone","volume":"26","author":"Janssens","year":"2005","journal-title":"Endocr Rev."},{"issue":"7","key":"bib9-20230712","doi-asserted-by":"crossref","first-page":"1865","DOI":"10.1148\/rg.317115093","article-title":"Sclerosing bone dysplasias: review and differentiation from other causes of 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