{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T14:42:27Z","timestamp":1787755347424,"version":"build-2784847793"},"reference-count":18,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JBJS Case Connector"],"abstract":"<jats:sec>\n                    <jats:title>Case:<\/jats:title>\n                    <jats:p>A 19-year-old adolescent with Kniest dysplasia was incidentally found to have osteosarcoma of the proximal aspect of the humerus after having a chest radiograph for evaluation of an upper respiratory infection. He underwent chemotherapy and resection of the tumor, and there was no evidence of metastasis at the 16-month follow-up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Patients with osteochondrodysplasias often have multiple orthopaedic symptoms. Changes in chronic pain symptoms should be investigated to rule out insidious secondary causes of musculoskeletal pain, such as osteosarcoma.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2106\/jbjs.cc.18.00047","type":"journal-article","created":{"date-parts":[[2018,10,9]],"date-time":"2018-10-09T21:48:57Z","timestamp":1539121737000},"page":"e78-e78","source":"Crossref","is-referenced-by-count":0,"title":["Osteosarcoma in an Adolescent with Kniest Dysplasia"],"prefix":"10.2106","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3844-9984","authenticated-orcid":false,"given":"Allison","family":"Tetreault","sequence":"first","affiliation":[{"name":"Musculoskeletal Research Center, Department of Orthopaedic Surgery, Children\u2019s Hospital Colorado, Aurora, Colorado"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3316-1228","authenticated-orcid":false,"given":"Wendy","family":"Ramalingam","sequence":"additional","affiliation":[{"name":"Musculoskeletal Research Center, Department of Orthopaedic Surgery, Children\u2019s Hospital Colorado, Aurora, Colorado"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2181-9344","authenticated-orcid":false,"given":"Jennifer","family":"Black","sequence":"additional","affiliation":[{"name":"Department of Pathology, Children\u2019s Hospital Colorado, Aurora, Colorado"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8107-3943","authenticated-orcid":false,"given":"Nancy H.","family":"Miller","sequence":"additional","affiliation":[{"name":"Musculoskeletal Research Center, Department of Orthopaedic Surgery, Children\u2019s Hospital Colorado, Aurora, Colorado"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6595-804X","authenticated-orcid":false,"given":"Nathan","family":"Donaldson","sequence":"additional","affiliation":[{"name":"Musculoskeletal Research Center, Department of Orthopaedic Surgery, Children\u2019s Hospital Colorado, Aurora, Colorado"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2018,12]]},"reference":[{"issue":"5","key":"bib1-20230713","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1097\/01241398-200009000-00010","article-title":"The genetic basis of the osteochondrodysplasias","volume":"20","author":"Baitner","year":"2000","journal-title":"J Pediatr Orthop."},{"issue":"6","key":"bib2-20230713","first-page":"1128","article-title":"Expression, in cartilage, of a 7-amino-acid deletion in type II collagen from two unrelated individuals with Kniest dysplasia","volume":"55","author":"Bogaert","year":"1994","journal-title":"Am J Hum Genet."},{"issue":"11","key":"bib3-20230713","doi-asserted-by":"crossref","first-page":"1266","DOI":"10.1203\/00006450-197911000-00012","article-title":"Kniest dysplasia. 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