{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T14:43:22Z","timestamp":1787755402055,"version":"build-2784847793"},"reference-count":5,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JBJS Case Connector"],"abstract":"<jats:sec>\n                    <jats:title>Case:<\/jats:title>\n                    <jats:p>We present an unusual case of a distal metaphyseal femur insufficiency fracture in an adolescent with a history of multiple low-energy appendicular fractures. A genetic workup was significant for a variant of unknown significance to the Col1A1 gene.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>To our knowledge, this is the first report of this collagen gene variant as a risk factor for multiple fractures. The case illustrates the presentation of this gene\u2019s phenotype and suggested medical management.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2106\/jbjs.cc.18.00317","type":"journal-article","created":{"date-parts":[[2019,9,15]],"date-time":"2019-09-15T13:40:00Z","timestamp":1568554800000},"page":"e0317-e0317","source":"Crossref","is-referenced-by-count":0,"title":["Distal Femur Insufficiency Fracture in a Pediatric Patient: An Atypical Presentation of Osteogenesis Imperfecta"],"prefix":"10.2106","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2859-0263","authenticated-orcid":false,"given":"Kessiena L.","family":"Aya","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery and Rehabilitation, The University of Texas Medical Branch, Galveston, Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5612-0058","authenticated-orcid":false,"given":"Kelly D.","family":"Carmichael","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery and Rehabilitation, The University of Texas Medical Branch, Galveston, Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1621-3214","authenticated-orcid":false,"given":"Matthew","family":"Igbinigie","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery and Rehabilitation, The University of Texas Medical Branch, Galveston, Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2019]]},"reference":[{"issue":"310","key":"bib1-20230712","first-page":"165","article-title":"Stress fractures of the femoral diaphysis in young children: a report of 2 cases","author":"Buckley","year":"1995","journal-title":"Clin Orthop Relat Res."},{"issue":"2","key":"bib2-20230712","doi-asserted-by":"crossref","first-page":"245","DOI":"10.2214\/ajr.159.2.1632335","article-title":"Stress fractures: current concepts","volume":"159","author":"Daffner","year":"1992","journal-title":"AJR Am J Roentgenol."},{"issue":"742","key":"bib3-20230712","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1259\/0007-1285-62-742-893","article-title":"Fatigue fractures of the femoral diaphysis in the skeletally immature simulating malignancy","volume":"62","author":"Davies","year":"1989","journal-title":"Br J Radiol."},{"issue":"7","key":"bib4-20230712","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1136\/jmg.28.7.433","article-title":"Osteogenesis imperfecta: translation of mutation to phenotype","volume":"28","author":"Byers","year":"1991","journal-title":"J Med Genet."},{"issue":"3","key":"bib5-20230712","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.anpedi.2013.01.019","article-title":"Idiopathic juvenile osteoporosis [in Spanish]","volume":"79","author":"Guagnelli","year":"2013","journal-title":"An Pediatr (Barc)."}],"container-title":["JBJS Case Connector"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.2106\/JBJS.CC.18.00317","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T13:42:35Z","timestamp":1787751755000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.2106\/JBJS.CC.18.00317"}},"subtitle":["A Case Report"],"short-title":[],"issued":{"date-parts":[[2019]]},"references-count":5,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2019]]}},"URL":"https:\/\/doi.org\/10.2106\/jbjs.cc.18.00317","relation":{},"ISSN":["2160-3251"],"issn-type":[{"value":"2160-3251","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019]]}}}