{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T14:47:25Z","timestamp":1787755645953,"version":"build-2784847793"},"reference-count":28,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"\n Case:<\/jats:title>\n \n We present a 23-year-old woman on immunosuppressive therapy with polyarticular, culture-negative septic arthritis. She underwent irrigation and debridement with empiric antibiotic therapy but had recurrence of septic arthritis despite treatment. Polymerase chain reaction testing eventually identified\n Ureaplasma<\/jats:italic>\n as the causative organism. She was successfully treated with an extended course of organism-specific antibiotics.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n More patients are being treated with immune modulating therapies. Immunosuppressed patients are at risk for atypical infections and may have different presentations than immunocompetent patients. Newer diagnostic modalities can help identify causative organisms and direct treatment in the case of negative cultures.<\/jats:p>\n <\/jats:sec>","DOI":"10.2106\/jbjs.cc.20.00057","type":"journal-article","created":{"date-parts":[[2020,7,16]],"date-time":"2020-07-16T10:15:40Z","timestamp":1594894540000},"page":"e20.00057-e20.00057","source":"Crossref","is-referenced-by-count":3,"title":["Diagnosis of Culture-Negative Septic Arthritis with Polymerase Chain Reaction in an Immunosuppressed Patient"],"prefix":"10.2106","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3284-4606","authenticated-orcid":false,"given":"Zachariah G.","family":"Whiting","sequence":"first","affiliation":[{"name":"The George Washington University School of Medicine and Health Sciences, Washington, District of Columbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2805-1152","authenticated-orcid":false,"given":"Teresa","family":"Doerre","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, The George Washington University School of Medicine and Health Sciences, Washington, District of Columbia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2020]]},"reference":[{"issue":"9717","key":"bib1-20230720","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1016\/S0140-6736(09)61595-6","article-title":"Bacterial septic arthritis in adults","volume":"375","author":"Mathews","year":"2010","journal-title":"Lancet."},{"issue":"2","key":"bib2-20230720","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1136\/emj.2006.037929","article-title":"Diagnostic utility of laboratory tests in septic 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