{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T14:45:49Z","timestamp":1787755549499,"version":"build-2784847793"},"reference-count":24,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:sec>\n                    <jats:title>Case:<\/jats:title>\n                    <jats:p>A 29-year-old motor vehicle collision passenger presented with fractures of the pelvic ring, bilateral femurs, and right tibia\/fibula. All fractures were stabilized with external fixation and fixed definitively 48 hours later. Postoperatively, the patient suffered rapid clinical decline. Emergent head computed tomography (CT) demonstrated tonsillar herniation with loss of gray-white matter differentiation. Although respiratory status remained uncompromised throughout presentation, pathology revealed extensive cerebral fat embolism.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Fat embolism can traverse the lungs without eliciting an inflammatory response, radiographic infiltrate, or impairing gas exchange. This may lead to a clinically silent, fatal cerebral fat embolism in an intubated, sedated patient.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2106\/jbjs.cc.20.00127","type":"journal-article","created":{"date-parts":[[2020,11,24]],"date-time":"2020-11-24T18:51:47Z","timestamp":1606243907000},"page":"e20.00127-e20.00127","source":"Crossref","is-referenced-by-count":0,"title":["Fatal Cerebral Fat Embolism After Pelvic and Multiple Long Bone Fractures without Associated Lung Injury"],"prefix":"10.2106","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8574-636X","authenticated-orcid":false,"given":"William J.","family":"Hadden","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery, The Ottawa Hospital, Ottawa, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6436-8686","authenticated-orcid":false,"given":"Brent","family":"Herritt","sequence":"additional","affiliation":[{"name":"Department of Critical Care, The Ottawa Hospital, Ottawa, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5409-3308","authenticated-orcid":false,"given":"Richard","family":"Hoang","sequence":"additional","affiliation":[{"name":"Department of Critical Care, The Ottawa Hospital, Ottawa, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1522-1423","authenticated-orcid":false,"given":"Christopher","family":"Milroy","sequence":"additional","affiliation":[{"name":"Department of Pathology, The Ottawa Hospital, Ottawa, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9525-2272","authenticated-orcid":false,"given":"John","family":"Hooper","sequence":"additional","affiliation":[{"name":"Department of Critical Care, The Ottawa Hospital, Ottawa, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9807-7916","authenticated-orcid":false,"given":"Geoffrey","family":"Wilkin","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, The Ottawa Hospital, Ottawa, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2020]]},"reference":[{"key":"bib1-20230719","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1054\/arth.2001.21457","article-title":"Systemic fat and thrombus embolization in patients undergoing total knee arthroplasty with regional heparinization","volume":"16","author":"Giachino","year":"2001","journal-title":"J Arthroplasty."},{"key":"bib2-20230719","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1097\/MAJ.0b013e318172f5d2","article-title":"Fat embolism syndrome","volume":"336","author":"Stein","year":"2008","journal-title":"Am J Med Sci."},{"key":"bib3-20230719","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/S1726-4901(10)70088-5","article-title":"Fat embolism syndrome in long bone fracture\u2014clinical experience in a tertiary referral center in Taiwan","volume":"73","author":"Tsai","year":"2010","journal-title":"J Chin Med Assoc."},{"key":"bib4-20230719","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1302\/0301-620X.52B4.732","article-title":"Fat embolism: an aid to diagnosis","volume":"52","author":"Gurd","year":"1970","journal-title":"J Bone Joint Surg Br Vol."},{"key":"bib5-20230719","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1302\/0301-620X.69B1.3818718","article-title":"Fat embolism and the fat embolism syndrome. 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