{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T14:45:17Z","timestamp":1787755517992,"version":"build-2784847793"},"reference-count":19,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:sec>\n                    <jats:title>Case:<\/jats:title>\n                    <jats:p>A 69-year-old woman presented with a painful mass at her first metatarsophalangeal joint. Further evaluation was concerning for a neoplastic process, leading to surgical intervention. Pathological examination demonstrated hemosiderotic synovitis, and hematologic evaluation led to a new diagnosis of von Willebrand disease.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Hemorrhagic synovitis, involving mostly larger joints, has been well described. However, a literature search demonstrates no cases of this in the foot or toes. Presentation of hemarthroses and underlying coagulopathies can be subtle and must be considered in patients presenting with soft-tissue masses or pseudotumors, despite having no previous diagnosis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2106\/jbjs.cc.20.00168","type":"journal-article","created":{"date-parts":[[2020,7,24]],"date-time":"2020-07-24T11:00:59Z","timestamp":1595588459000},"page":"e20.00168-e20.00168","source":"Crossref","is-referenced-by-count":2,"title":["Hemorrhagic Synovitis of the First Metatarsophalangeal Joint"],"prefix":"10.2106","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6769-9475","authenticated-orcid":false,"given":"William P.","family":"Ensminger","sequence":"first","affiliation":[{"name":"Department of Orthopedic Surgery, University of Kansas Medical Center Kansas City, Kansas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6170-6635","authenticated-orcid":false,"given":"Elizabeth","family":"Friedman","sequence":"additional","affiliation":[{"name":"Department of Pathology, University of Kansas Medical Center, Kansas City, Kansas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7805-2658","authenticated-orcid":false,"given":"Kimberly J.","family":"Templeton","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, University of Kansas Medical Center Kansas City, Kansas"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2020]]},"reference":[{"issue":"1","key":"bib1-20230720","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1186\/s12885-018-4648-3","article-title":"Distribution patterns of foot and ankle tumors: a university tumor institute experience","volume":"18","author":"Toepfer","year":"2018","journal-title":"BMC Cancer."},{"issue":"3","key":"bib2-20230720","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1308\/003588407X168235","article-title":"The differential diagnosis of foot lumps: 101 cases treated surgically in North Glasgow over 4 years","volume":"89","author":"MacDonald","year":"2007","journal-title":"Ann R Coll Surg Eng."},{"issue":"4","key":"bib3-20230720","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1007\/s13244-011-0087-2","article-title":"Pseudotumoural soft tissue lesions of the foot and ankle: a pictorial review","volume":"2","author":"Van Hul","year":"2011","journal-title":"Insights Imaging."},{"issue":"5","key":"bib4-20230720","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1309\/LWW3-5XK0-FKG9-HDRK","article-title":"Pathology of the synovium","volume":"114","author":"O'Connell","year":"2000","journal-title":"Am J Clin Pathol."},{"key":"bib5-20230720","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1097\/00003086-199101000-00019","article-title":"Nonhemophilic hemosiderotic synovitis of the shoulder. A case report","volume":"262","author":"France","year":"1991","journal-title":"Clin Orthop Relat Res."},{"issue":"6","key":"bib6-20230720","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/j.blre.2012.09.002","article-title":"Hemophilic arthropathy in patients with von Willebrand disease","volume":"26","author":"van Galen","year":"2012","journal-title":"Blood Rev."},{"issue":"1","key":"bib7-20230720","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1182\/asheducation-2014.1.524","article-title":"Clinical and laboratory diagnosis of VWD","volume":"2014","author":"Federici","year":"2014","journal-title":"Hematol Am Soc Hematol Educ Program."},{"issue":"6","key":"bib8-20230720","first-page":"391","article-title":"von Willebrand's disease with haemarthrosis (a case report)","volume":"24","author":"Misra","year":"1976","journal-title":"J Assoc Physicians India."},{"issue":"3","key":"bib9-20230720","doi-asserted-by":"crossref","first-page":"e185","DOI":"10.1111\/hae.12670","article-title":"Joint bleeds in von Willebrand disease patients have significant impact on quality of life and joint integrity: a cross-sectional study","volume":"21","author":"van Galen","year":"2015","journal-title":"Haemophilia."},{"issue":"1","key":"bib10-20230720","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1007\/BF02031077","article-title":"Arthropathy in von Willebrand's disease","volume":"8","author":"MacFarlane","year":"1989","journal-title":"Clin Rheumatol."},{"issue":"5","key":"bib11-20230720","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1111\/j.1365-2516.2005.01133.x","article-title":"Outcome of surgical concepts in haemophilic arthropathy of the hindfoot","volume":"11","author":"Panotopoulos","year":"2005","journal-title":"Haemophilia."},{"issue":"2","key":"bib12-20230720","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1136\/emj.16.2.153","article-title":"An acutely painful elbow as a first presentation of von Willebrand's disease","volume":"16","author":"Poncia","year":"1999","journal-title":"J Accid Emerg Med."},{"issue":"2","key":"bib13-20230720","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1111\/j.1365-2257.1983.tb01347.x","article-title":"Chronic arthropathy in von Willebrand's disease","volume":"5","author":"Sankarankutty","year":"1983","journal-title":"Clin Lab Haematol."},{"issue":"1","key":"bib14-20230720","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1111\/hae.12258","article-title":"Orthopaedic surgery in patients with von Willebrand disease","volume":"20","author":"Siboni","year":"2014","journal-title":"Haemophilia."},{"issue":"8","key":"bib15-20230720","doi-asserted-by":"crossref","first-page":"1465","DOI":"10.1160\/TH16-12-0967","article-title":"Joint assessment in von Willebrand disease. 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