{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T14:37:14Z","timestamp":1787755034314,"version":"build-2784847793"},"reference-count":27,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec>\n                    <jats:title>Case:<\/jats:title>\n                    <jats:p>We present a 36-year-old man with L1 burst fracture after a sneeze. He was in follow-up for indolent systemic mastocytosis (ISM), and osteoporosis was treated with bisphosphonate. Owing to neurologic impairment, posterior decompressive laminectomy and thoraco-lumbar fusion with cemented screws were performed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Vertebral fractures in young patients affected by ISM required a multidisciplinary approach and a careful preoperative planning to achieve acceptable results. These fractures are so rare that even an experienced spine surgeon may not come across them during his whole career. Nevertheless, diagnostic tool improvement makes its diagnosis more frequent, that is why every spine surgeon should know this disease.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2106\/jbjs.cc.20.00259","type":"journal-article","created":{"date-parts":[[2021,8,27]],"date-time":"2021-08-27T15:00:15Z","timestamp":1630076415000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Management of a Lumbar Burst Fracture Occurring After a Sneeze in a Patient Affected by Systemic Mastocytosis"],"prefix":"10.2106","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7411-0355","authenticated-orcid":false,"given":"Federico","family":"De Iure","sequence":"first","affiliation":[{"name":"Department of Spine Surgery \u2013 Maggiore Hospital, Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2052-4437","authenticated-orcid":false,"given":"Luca","family":"Amendola","sequence":"additional","affiliation":[{"name":"Department of Orthopedics and Traumatology \u2013 Maggiore Hospital, Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2853-2178","authenticated-orcid":false,"given":"Daniele","family":"Fabbri","sequence":"additional","affiliation":[{"name":"Department of Orthopedics \u2013 IRCCS Orthopedic Institute Galeazzi, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3068-9764","authenticated-orcid":false,"given":"Mohammadreza","family":"Chehrassan","sequence":"additional","affiliation":[{"name":"Department of Orthopedics and Traumatology \u2013 Shahid Beheshti University of Medical Sciences, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0176-2889","authenticated-orcid":false,"given":"Alessandro","family":"Corghi","sequence":"additional","affiliation":[{"name":"Department of Orthopedics and Traumatology \u2013 Maggiore Hospital, Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7096-1964","authenticated-orcid":false,"given":"Michele","family":"Cappuccio","sequence":"additional","affiliation":[{"name":"Department of Spine Surgery \u2013 Maggiore Hospital, Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2021,7]]},"reference":[{"issue":"2","key":"bib1-20240805","first-page":"159","article-title":"Mastocytosis: a paradigmatic example of a rare disease with complex biology and pathology","volume":"3","author":"Valent","year":"2013","journal-title":"Am J Cancer Res."},{"issue":"12","key":"bib2-20240805","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1001\/archderm.1983.01650360067017","article-title":"Monozygotic twins discordant for cutaneous mastocytosis","volume":"119","author":"Cainelli","year":"1983","journal-title":"Arch Dermatol."},{"issue":"3","key":"bib3-20240805","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1016\/j.jaci.2012.04.013","article-title":"Adult-onset systemic mastocytosis in monozygotic twins with KIT D816V and JAK2 V617F mutations","volume":"130","author":"Broesby-Olsen","year":"2012","journal-title":"J Allergy Clin Immunol."},{"issue":"4","key":"bib4-20240805","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1046\/j.1525-1470.2001.01939.x","article-title":"Familial cutaneous mastocytosis","volume":"18","author":"Chang","year":"2001","journal-title":"Pediatr Dermatol."},{"issue":"6","key":"bib5-20240805","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1111\/j.1365-2362.2007.01807.x","article-title":"Standards and standardization in mastocytosis: consensus statements on diagnostics, treatment recommendations and response criteria","volume":"37","author":"Valent","year":"2007","journal-title":"Eur J Clin Invest."},{"issue":"3","key":"bib6-20240805","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1111\/joim.12410","article-title":"Mastocytosis: the puzzling clinical spectrum and challenging diagnostic aspects of an enigmatic disease","volume":"279","author":"G\u00fclen","year":"2016","journal-title":"J Intern Med."},{"issue":"9","key":"bib7-20240805","doi-asserted-by":"crossref","first-page":"1691","DOI":"10.1093\/annonc\/mdu047","article-title":"Refined diagnostic criteria and classification of mast cell leukemia (MCL) and myelomastocytic leukemia (MML): a consensus proposal","volume":"25","author":"Valent","year":"2014","journal-title":"Ann Oncol."},{"issue":"10","key":"bib8-20240805","doi-asserted-by":"crossref","first-page":"1838","DOI":"10.1136\/ard.2009.124511","article-title":"Systemic mastocytosis and bone involvement in a cohort of 75 patients","volume":"69","author":"Barete","year":"2010","journal-title":"Ann Rheum Dis."},{"issue":"3","key":"bib9-20240805","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1111\/j.1398-9995.2011.02780.x","article-title":"High prevalence of fractures and osteoporosis in patients with indolent systemic mastocytosis","volume":"67","author":"Van der Veer","year":"2012","journal-title":"Allergy."},{"issue":"3","key":"bib10-20240805","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1016\/j.iac.2006.05.002","article-title":"Diagnostic evaluation and classification of mastocytosis","volume":"26","author":"Valent","year":"2006","journal-title":"Immunol Allergy Clin North Am."},{"issue":"5","key":"bib11-20240805","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1097\/PAS.0b013e31824c0d92","article-title":"Malignant transformation of mastocytoma developed on skin mastocytosis into cutaneous mast cell sarcoma","volume":"36","author":"Auquit-Auckbur","year":"2012","journal-title":"Am J Surg Pathol."},{"issue":"3","key":"bib12-20240805","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/j.iac.2006.05.006","article-title":"Systemic mastocytosis: clinical manifestations and differential diagnosis","volume":"26","author":"Butterfield","year":"2006","journal-title":"Immunol Allergy Clin North Am."},{"issue":"1","key":"bib13-20240805","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1007\/s10067-005-1132-7","article-title":"Transiliac bone biopsy in osteoporosis: frequency, indications, consequences and complications. An evaluation of 99 consecutive cases over a period of 14 years","volume":"25","author":"Kann","year":"2006","journal-title":"Clin Rheumatol."},{"issue":"1","key":"bib14-20240805","first-page":"44","article-title":"Diagnosis and management of vertebral compression fractures","volume":"94","author":"McCarthy","year":"2016","journal-title":"Am Fam Physician."},{"issue":"17","key":"bib15-20240805","doi-asserted-by":"crossref","first-page":"E626","DOI":"10.1097\/BRS.0b013e3181a6bc4f","article-title":"Multimodal therapy for vertebral involvement of systemic mastocytosis","volume":"34","author":"Kr\u00fcger","year":"2009","journal-title":"Spine."},{"issue":"4","key":"bib16-20240805","first-page":"290","article-title":"A 41-years-old man with a vertebral fracture and bone marrow mastocytosis","volume":"10","author":"Makras","year":"2010","journal-title":"J Musculoskelet Neuronal Interact."},{"issue":"6","key":"bib17-20240805","first-page":"326","article-title":"Mast cell leukaemia presenting with multiple osteoporotic fractures in an elderly woman","volume":"72","author":"de Boer","year":"2014","journal-title":"Neth J Med."},{"issue":"1","key":"bib18-20240805","first-page":"97","article-title":"Osteoporosis with vertebral fractures in young males, due to bone marrow mastocytosis: a report of two cases","volume":"28","author":"Manara","year":"2010","journal-title":"Clin Exp Rheumatol."},{"issue":"2","key":"bib19-20240805","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.iac.2014.01.011","article-title":"Bone involvement and osteoporosis in mastocytosis","volume":"34","author":"Rossini","year":"2014","journal-title":"Immunol Allergy Clin North Am."},{"issue":"3","key":"bib20-20240805","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1097\/00002517-200006000-00006","article-title":"Biomechanical evaluation and preliminary clinical experience with an expansive pedicle screw design","volume":"13","author":"Cook","year":"2000","journal-title":"J Spinal Disord."},{"issue":"3","key":"bib21-20240805","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/j.spinee.2004.11.010","article-title":"Hydroxyapatite-coating of pedicle screws improves resistance against pull-out force in the osteoporotic canine lumbar spine model: a pilot study","volume":"5","author":"Hasegawa","year":"2005","journal-title":"Spine J."},{"issue":"4","key":"bib22-20240805","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1007\/s10195-011-0164-9","article-title":"Fenestrated pedicle screws for cement-augmented purchase in patients with bone softening: a review of 21 cases","volume":"12","author":"Amendola","year":"2011","journal-title":"J Orthop Traumatol."},{"issue":"10","key":"bib23-20240805","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1213\/XAA.0000000000001093","article-title":"Undiagnosed systemic mastocytosis presenting as postoperative distributive shock: a case report","volume":"13","author":"Ripoll","year":"2019","journal-title":"A A Pract."},{"key":"bib24-20240805","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.jclinane.2018.06.047","article-title":"Anesthetic management of patients with systemic mastocytosis","volume":"50","author":"Ishii","year":"2018","journal-title":"J Clin Anesth."},{"issue":"4","key":"bib25-20240805","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1016\/j.anai.2017.07.022","article-title":"Management around invasive procedures in mastocytosis: an update","volume":"119","author":"Hermans","year":"2017","journal-title":"Ann Allergy Asthma Immunol."},{"issue":"6","key":"bib26-20240805","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1093\/bja\/65.6.833","article-title":"Massive histamine release in a patient with systemic mastocytosis","volume":"65","author":"Desborough","year":"1990","journal-title":"Br J Anaesth."},{"issue":"3","key":"bib27-20240805","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1177\/1076029607309173","article-title":"Fatal bleeding due to a heparin-like anticoagulant in a 37-year-old woman suffering from systemic mastocytosis","volume":"14","author":"Sucker","year":"2008","journal-title":"Clin Appl Thromb Hemost."}],"container-title":["JBJS Case Connector"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.2106\/JBJS.CC.20.00259","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T13:36:30Z","timestamp":1787751390000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.2106\/JBJS.CC.20.00259"}},"subtitle":["A Case Report"],"short-title":[],"issued":{"date-parts":[[2021,7]]},"references-count":27,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.2106\/jbjs.cc.20.00259","relation":{},"ISSN":["2160-3251"],"issn-type":[{"value":"2160-3251","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,7]]}}}