{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T14:39:14Z","timestamp":1787755154738,"version":"build-2784847793"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec>\n                    <jats:title>Case:<\/jats:title>\n                    <jats:p>Here, we present the case of a pediatric polytrauma patient found to have lower extremity intra-arterial fat embolism causing ischemic necrosis and ultimately necessitating below-the-knee amputation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Fat embolism, a common complication of long bone fractures in adults, can be associated with significant morbidity. Although rare, it should be considered among the possible etiologies for a pulseless limb after trauma. Early fracture stabilization may prevent fat embolism and fat embolism syndrome; however, there is no known definitive treatment, and management is supportive.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2106\/jbjs.cc.20.00485","type":"journal-article","created":{"date-parts":[[2021,7,8]],"date-time":"2021-07-08T14:06:11Z","timestamp":1625753171000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Arterial Fat Embolism in a Pediatric Patient with Femur Fracture"],"prefix":"10.2106","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1436-2390","authenticated-orcid":false,"given":"Regina","family":"Toto","sequence":"first","affiliation":[{"name":"Division of Emergency Medicine, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eron Y.","family":"Friedlaender","sequence":"additional","affiliation":[{"name":"Division of Emergency Medicine, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4468-2950","authenticated-orcid":false,"given":"Gary W.","family":"Nace","sequence":"additional","affiliation":[{"name":"Division of General, Thoracic and Fetal Surgery and Trauma Center, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7171-9835","authenticated-orcid":false,"given":"Alexandre","family":"Arkader","sequence":"additional","affiliation":[{"name":"Division of Orthopedics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L. Scott","family":"Levin","sequence":"additional","affiliation":[{"name":"Division of Orthopedics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania"},{"name":"Departments of Orthopedic Surgery and Plastic Surgery, University of Pennsylvania, Philadelphia, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2021,7]]},"reference":[{"issue":"1","key":"bib1-20240809","doi-asserted-by":"crossref","first-page":"221.e1","DOI":"10.1016\/j.jcrc.2014.09.008","article-title":"Fat embolism in pediatric patients: an autopsy evaluation of incidence and etiology","volume":"30","author":"Eriksson","year":"2015","journal-title":"J Crit Care."},{"issue":"4","key":"bib2-20240809","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1177\/1460408610396026","article-title":"Fat embolism syndrome: what have we learned over the years?","volume":"13","author":"Tzioupis","year":"2011","journal-title":"Trauma."},{"key":"bib3-20240809","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1046\/j.1365-2044.2001.01724.x","article-title":"Fat embolism","volume":"56","author":"Mellor","year":"2001","journal-title":"Anesthesia."},{"key":"bib4-20240809","doi-asserted-by":"crossref","first-page":"e346","DOI":"10.5435\/JAAOS-D-17-00571","article-title":"Fat embolism and fat embolism syndrome","volume":"27","author":"Rothberg","year":"2019","journal-title":"J Am Acad Orthop Surg."},{"issue":"4","key":"bib5-20240809","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1001\/archsurg.1997.01430280109019","article-title":"Fat embolism syndrome: a 10-year review","volume":"132","author":"Bulger","year":"1997","journal-title":"Arch Surg."},{"issue":"4","key":"bib6-20240809","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1302\/0301-620X.52B4.732","article-title":"Fat embolism: an aid to diagnosis","volume":"52B","author":"Gurd","year":"1970","journal-title":"J Bone Joint Surg Br."},{"key":"bib7-20240809","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1161\/CIRCULATIONAHA.114.010835","article-title":"Fat embolism syndrome","volume":"131","author":"Kosova","year":"2015","journal-title":"Circulation."},{"key":"bib8-20240809","doi-asserted-by":"crossref","first-page":"S8","DOI":"10.1016\/j.injury.2006.08.036","article-title":"Bone marrow fat in the circulation: clinical entities and pathophysiological mechanisms","volume":"375","author":"Husebye","year":"2006","journal-title":"Injury."},{"key":"bib9-20240809","article-title":"The fat embolism syndrome as a cause of paraplegia","volume":"6","author":"Peters","year":"2018","journal-title":"Sage Open Med Case Rep."},{"issue":"5","key":"bib10-20240809","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1097\/BOT.0000000000000246","article-title":"A lower extremity musculoskeletal and vascular trauma protocol in a children's hospital may improve treatment response times and appropriate microvascular coverage","volume":"29","author":"Gans","year":"2015","journal-title":"J Orthop Trauma."}],"container-title":["JBJS Case Connector"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.2106\/JBJS.CC.20.00485","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T13:38:26Z","timestamp":1787751506000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.2106\/JBJS.CC.20.00485"}},"subtitle":["A Case Report"],"short-title":[],"issued":{"date-parts":[[2021,7]]},"references-count":10,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.2106\/jbjs.cc.20.00485","relation":{},"ISSN":["2160-3251"],"issn-type":[{"value":"2160-3251","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,7]]}}}