{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T14:38:55Z","timestamp":1787755135387,"version":"build-2784847793"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec>\n                    <jats:title>Case:<\/jats:title>\n                    <jats:p>The phenomenon of acro-osteolysis often intrigues clinicians and patients alike, as it causes bone resorption. One such condition is Hajdu-Cheney syndrome. We report our experience in identifying and halting the active bone resorption in a patient and his father with 2-year follow-up results.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Management included identification of the NOTCH2 mutation and treatment with antiresorptive measures. In addition, genetic counseling and antenatal counseling are recommended to explain the risk of inheritance.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2106\/jbjs.cc.20.00711","type":"journal-article","created":{"date-parts":[[2021,5,21]],"date-time":"2021-05-21T14:06:52Z","timestamp":1621606012000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Hajdu-Cheney Syndrome"],"prefix":"10.2106","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7468-1414","authenticated-orcid":false,"given":"Gopinath","family":"Duraiswamy","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery, Consultant Orthopaedic Surgeon, Dr. Rela Institute and Medical Center, Chennai, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3657-9478","authenticated-orcid":false,"given":"Munis","family":"Ashraf","sequence":"additional","affiliation":[{"name":"Fellow in Arthroscopy and Sports Medicine, Senior Registrar, Ortho One Hospital, Coimbatore, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7074-9197","authenticated-orcid":false,"given":"Senthil Nathan","family":"Sambandam","sequence":"additional","affiliation":[{"name":"Consultant Orthopaedic Surgeon, Department of Orthopaedic Surgery, Boston VA Medical center, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3953-0968","authenticated-orcid":false,"given":"Saseendar","family":"Shanmugasundaram","sequence":"additional","affiliation":[{"name":"Consultant Shoulder and Knee Arthroscopy Surgeon, Apollo Hospital, Muscat, Sultanate of Oman"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2021,4]]},"reference":[{"issue":"241","key":"bib1-20240805","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1259\/0007-1285-21-241-42","article-title":"Cranio-skeletal dysplasia","volume":"21","author":"Hajdu","year":"1948","journal-title":"Br J Radiol."},{"issue":"1","key":"bib2-20240805","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1186\/s13023-014-0200-y","article-title":"Hajdu-Cheney syndrome: a review","volume":"9","author":"Canalis","year":"2014","journal-title":"Orphanet J Rare Dis."},{"issue":"1","key":"bib3-20240805","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12891-020-3181-0","article-title":"Distinct severity of phenotype in Hajdu-Cheney syndrome: a case report and literature review","volume":"21","author":"Zeng","year":"2020","journal-title":"BMC Musculoskelet 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Am."},{"issue":"2","key":"bib7-20240805","first-page":"169","article-title":"Hajdu-Cheney syndrome: case report","volume":"20","author":"Prabhu","year":"1996","journal-title":"J Clin Pediatr Dentistry."},{"issue":"9","key":"bib8-20240805","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3941\/jrcr.v8i9.1833","article-title":"Hajdu-Cheney syndrome: a case report with review of literature","volume":"8","author":"Palav","year":"2014","journal-title":"J Radiol case Rep."},{"issue":"5","key":"bib9-20240805","doi-asserted-by":"crossref","first-page":"663","DOI":"10.4103\/0971-5916.187117","article-title":"Hajdu-Cheney syndrome-a rare cause of micrognathia","volume":"143","author":"Amalnath","year":"2016","journal-title":"Indian J Med Res."},{"issue":"2","key":"bib10-20240805","first-page":"OD07","article-title":"Hajdu Cheney syndrome","volume":"10","author":"Samuel","year":"2016","journal-title":"J Clin Diagn Res."}],"container-title":["JBJS Case Connector"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.2106\/JBJS.CC.20.00711","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T13:38:09Z","timestamp":1787751489000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.2106\/JBJS.CC.20.00711"}},"subtitle":["A Report on Successful Halting of Acro-osteolysis"],"short-title":[],"issued":{"date-parts":[[2021,4]]},"references-count":10,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.2106\/jbjs.cc.20.00711","relation":{},"ISSN":["2160-3251"],"issn-type":[{"value":"2160-3251","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,4]]}}}