{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T14:23:41Z","timestamp":1787754221716,"version":"build-2784847793"},"reference-count":20,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec>\n                    <jats:title>Case:<\/jats:title>\n                    <jats:p>Erdheim-Chester's disease (ECD) is a rare multisystem disorder considered as a neoplasm of non\u2013Langerhans cell histiocytes. We report a case of uncemented total hip arthroplasty in a 74-year-old patient with ECD for femoral neck fracture with pathological involvement of distal metaphysis and diaphysis. We reviewed the literature on bony involvement.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Adequate osseointegration was achieved in our case; however, longer follow-up is essential. Vigilant reporting of bony involvement, such as pathological fractures, fracture healing, deformities, osteosynthesis, and outcome of joint replacement surgeries, is needed in ECD-like bone diseases.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2106\/jbjs.cc.20.01021","type":"journal-article","created":{"date-parts":[[2024,12,12]],"date-time":"2024-12-12T14:01:22Z","timestamp":1734012082000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Total Hip Replacement in a Patient with Erdheim-Chester's Disease"],"prefix":"10.2106","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6994-7994","authenticated-orcid":false,"given":"Ramneek","family":"Mahajan","sequence":"first","affiliation":[{"name":"Max Institute of Musculoskeletal Sciences, Max Super Speciality Hospital, Saket, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4247-7531","authenticated-orcid":false,"given":"Piyush","family":"Nashikkar","sequence":"additional","affiliation":[{"name":"Max Institute of Musculoskeletal Sciences, Max Super Speciality Hospital, Saket, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5831-6863","authenticated-orcid":false,"given":"Varun","family":"Khanna","sequence":"additional","affiliation":[{"name":"Max Institute of Musculoskeletal Sciences, Max Super Speciality Hospital, Saket, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,10]]},"reference":[{"key":"bib1-20241212","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1186\/1750-1172-8-137","article-title":"Erdheim-Chester Disease: a comprehensive review of the literature","volume":"8","author":"Mazor","year":"2013","journal-title":"Orphanet J Rare Dis."},{"issue":"22","key":"bib2-20241212","doi-asserted-by":"crossref","first-page":"1929","DOI":"10.1182\/blood.2019003507","article-title":"Erdheim-Chester disease: consensus recommendations for evaluation, diagnosis, and treatment in the molecular era","volume":"135","author":"Goyal","year":"2020","journal-title":"Blood."},{"issue":"1","key":"bib3-20241212","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1186\/s13023-020-01518-1","article-title":"Bone mineral density and bone microarchitecture in a cohort of patients with Erdheim-Chester Disease","volume":"15","author":"He","year":"2020","journal-title":"Orphanet J Rare Dis."},{"issue":"4","key":"bib4-20241212","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1182\/blood-2014-03-561381","article-title":"Consensus guidelines for the diagnosis and clinical management of Erdheim-Chester disease","volume":"124","author":"Diamond","year":"2014","journal-title":"Blood."},{"issue":"10","key":"bib5-20241212","doi-asserted-by":"crossref","first-page":"2783","DOI":"10.1182\/blood-2010-10-313510","article-title":"Systemic perturbation of cytokine and chemokine networks in Erdheim-Chester disease: a single-center series of 37 patients","volume":"117","author":"Arnaud","year":"2011","journal-title":"Blood."},{"issue":"2","key":"bib6-20241212","doi-asserted-by":"crossref","first-page":"e51","DOI":"10.1111\/bjh.16177","article-title":"Concomitant Erdheim-Chester disease and chronic myelomonocytic leukaemia: genomic insights into a common clonal origin","volume":"187","author":"Goyal","year":"2019","journal-title":"Br J Haematol."},{"issue":"1","key":"bib7-20241212","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.critrevonc.2015.02.004","article-title":"Erdheim-Chester disease: a systematic review","volume":"95","author":"Cives","year":"2015","journal-title":"Crit Rev Oncol Hematol."},{"issue":"2","key":"bib8-20241212","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/j.rdc.2013.02.011","article-title":"Erdheim-Chester disease","volume":"39","author":"Haroche","year":"2013","journal-title":"Rheum Dis Clin North Am."},{"issue":"6","key":"bib9-20241212","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1053\/hupa.2000.8229","article-title":"Erdheim-Chester disease: evidence for a disease entity different from Langerhans cell histiocytosis? Three cases with detailed radiological and immunohistochemical analysis","volume":"31","author":"Kenn","year":"2000","journal-title":"Hum Pathol."},{"issue":"2","key":"bib10-20241212","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1148\/radiol.2382041525","article-title":"Bone involvement in Erdheim-Chester disease: imaging findings including periostitis and partial epiphyseal involvement","volume":"238","author":"Dion","year":"2006","journal-title":"Radiology."},{"issue":"4","key":"bib11-20241212","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1038\/modpathol.2017.160","article-title":"The histopathology of Erdheim-Chester disease: a comprehensive review of a molecularly characterized cohort","volume":"31","author":"Ozkaya","year":"2018","journal-title":"Mod Pathol."},{"issue":"6","key":"bib12-20241212","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1007\/s00256-013-1793-2","article-title":"Erdheim-Chester disease: an unusual presentation of an uncommon disease","volume":"43","author":"Bindra","year":"2014","journal-title":"Skeletal Radiol."},{"issue":"4","key":"bib13-20241212","doi-asserted-by":"crossref","first-page":"e257","DOI":"10.1016\/j.spinee.2015.10.050","article-title":"Erdheim-Chester disease in thoracic spine: a rare case of compression fracture","volume":"16","author":"Caglar","year":"2016","journal-title":"Spine J."},{"issue":"6","key":"bib14-20241212","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1016\/S0212-6982(05)74190-2","article-title":"Occult femoral neck fracture in a patient with Erdheim-Chester disease [2in Spanish]","volume":"24","author":"Ramos-Font","year":"2005","journal-title":"Rev Esp Med Nucl."},{"issue":"7","key":"bib15-20241212","doi-asserted-by":"crossref","first-page":"e29","DOI":"10.2106\/JBJS.J.00025","article-title":"Total knee arthroplasty in a patient with Erdheim-Chester disease with massive joint destruction: a case report","volume":"93","author":"Steinert","year":"2011","journal-title":"J Bone Joint Surg Am."},{"issue":"4","key":"bib16-20241212","doi-asserted-by":"crossref","first-page":"357","DOI":"10.5312\/wjo.v8.i4.357","article-title":"Total hip arthroplasty in patients with Paget's disease of bone: a systematic review","volume":"8","author":"Hanna","year":"2017","journal-title":"World J Orthop."},{"key":"bib17-20241212","article-title":"A brief overview of cellular and molecular mechanisms of osseointegration","volume":"2015","author":"Hosseini","year":"2015","journal-title":"Int J Contemp Dent Med Rev"},{"issue":"3","key":"bib18-20241212","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/0022-3913(92)90399-U","article-title":"Implant rehabilitation in Erdheim-Chester disease: a clinical report","volume":"68","author":"Brahim","year":"1992","journal-title":"J Prosthet Dent."},{"issue":"4","key":"bib19-20241212","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.ejim.2015.03.004","article-title":"Erdheim-Chester disease","volume":"26","author":"Campochiaro","year":"2015","journal-title":"Eur J Intern Med."},{"issue":"2","key":"bib20-20241212","doi-asserted-by":"crossref","first-page":"e113","DOI":"10.1016\/S1470-2045(17)30031-1","article-title":"Histiocytoses: emerging neoplasia behind inflammation","volume":"18","author":"Haroche","year":"2017","journal-title":"Lancet Oncol."}],"container-title":["JBJS Case Connector"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.2106\/JBJS.CC.20.01021","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T13:24:16Z","timestamp":1787750656000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.2106\/JBJS.CC.20.01021"}},"subtitle":["A Case Report"],"short-title":[],"issued":{"date-parts":[[2022,10]]},"references-count":20,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.2106\/jbjs.cc.20.01021","relation":{},"ISSN":["2160-3251"],"issn-type":[{"value":"2160-3251","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,10]]}}}