{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T14:39:52Z","timestamp":1787755192717,"version":"build-2784847793"},"reference-count":31,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec>\n                    <jats:title>Case:<\/jats:title>\n                    <jats:p>We present a case of progressive paraplegia because of extramedullary hematopoiesis and pathological vertebral fracture in thalassemia patient. The various surgical techniques including larger pedicle screws, bicortical fixation, and convergent direction to improve pullout strength had been used secondary to osteoporotic bone and kyphotic deformity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Prompt diagnosis and awareness of the compromised bone quality of the thalassemic patient is essential to guide the proper management and produce the desire outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2106\/jbjs.cc.21.00089","type":"journal-article","created":{"date-parts":[[2021,9,9]],"date-time":"2021-09-09T18:25:18Z","timestamp":1631211918000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["A Progressive Paraplegic Patient with Thalassemia Because of Extramedullary Hematopoiesis and Vertebral Fracture"],"prefix":"10.2106","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5060-1435","authenticated-orcid":false,"given":"Chaisiri","family":"Chaichankul","sequence":"first","affiliation":[{"name":"Department of Orthopaedics, Phramongkutklao Hospital and College of Medicine, Bangkok, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9093-5288","authenticated-orcid":false,"given":"Nattawat","family":"Srichandraphan","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Phramongkutklao Hospital and College of Medicine, Bangkok, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5957-8761","authenticated-orcid":false,"given":"Chaiyos","family":"Chaichankul","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Veterans General Hospital, Bangkok, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2174-8515","authenticated-orcid":false,"given":"Pawin","family":"Gajaseni","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Phramongkutklao Hospital and College of Medicine, Bangkok, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2021,7]]},"reference":[{"issue":"4","key":"bib1-20240805","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1038\/35066048","article-title":"Phenotype-genotype relationships in monogenic disease: lessons from the thalassaemias","volume":"2","author":"Weatherall","year":"2001","journal-title":"Nat Rev Genet."},{"key":"bib2-20240805","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1111\/j.1749-6632.2010.05542.x","article-title":"Treatment options for thalassemia patients with 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