{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T14:45:27Z","timestamp":1787755527441,"version":"build-2784847793"},"reference-count":9,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"\n Case:<\/jats:title>\n An 11-year-old female patient presented to our clinic with a low-grade lateral ankle sprain that was subsequently treated with a lace-up ankle brace. On the reintroduction of weight bearing, the patient developed recurrent ankle pain and symptoms consistent with complex regional pain syndrome (CRPS) Type 1. On physical examination, the patient was found to have a concurrent chromhidrosis in the injured area, which is a novel presentation of CRPS.<\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n Patients with CRPS found to have superficial skin discoloration should be evaluated further to investigate for chromhidrosis. Early diagnosis can improve the treatment of CRPS and allow for appropriate management of varying manifestations, such as chromhidrosis.<\/jats:p>\n <\/jats:sec>","DOI":"10.2106\/jbjs.cc.21.00194","type":"journal-article","created":{"date-parts":[[2022,1,31]],"date-time":"2022-01-31T23:00:18Z","timestamp":1643670018000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Novel Presentation of Pediatric Complex Regional Pain Syndrome with Concurrent Chromhidrosis"],"prefix":"10.2106","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5946-916X","authenticated-orcid":false,"given":"Calum","family":"Wallace","sequence":"first","affiliation":[{"name":"Geisinger Commonwealth School of Medicine, Scranton, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8332-7601","authenticated-orcid":false,"given":"John L.","family":"Coulter","sequence":"additional","affiliation":[{"name":"Geisinger Commonwealth School of Medicine, Scranton, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5737-1676","authenticated-orcid":false,"given":"Nick","family":"Sebes","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Geisinger Medical Center, Danville, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9158-0674","authenticated-orcid":false,"given":"Mark","family":"Seeley","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Geisinger Medical Center, Danville, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2021,7]]},"reference":[{"issue":"7","key":"bib1-20240731","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1016\/S1474-4422(11)70106-5","article-title":"Clinical features and pathophysiology of complex regional pain syndrome","volume":"10","author":"Marinus","year":"2011","journal-title":"Lancet Neurol."},{"issue":"1","key":"bib2-20240731","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1186\/s12969-016-0090-8","article-title":"Pediatric complex regional pain syndrome: a review","volume":"14","author":"Weissmann","year":"2016","journal-title":"Pediatr Rheumatol Online J."},{"issue":"2","key":"bib3-20240731","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1111\/pme.12033","article-title":"Complex regional pain syndrome: practical diagnostic and treatment guidelines, 4th edition","volume":"14","author":"Harden","year":"2013","journal-title":"Pain Med."},{"issue":"6","key":"bib4-20240731","first-page":"621","article-title":"Invasive management for pediatric complex regional pain syndrome: literature review of evidence","volume":"18","author":"Rodriguez","year":"2015","journal-title":"Pain Physician."},{"issue":"2","key":"bib5-20240731","first-page":"193","article-title":"Reflex sympathetic dystrophy in a child. A case report","volume":"32","author":"Matles","year":"1971","journal-title":"Bull Hosp Joint Dis."},{"key":"bib6-20240731","first-page":"CD010853","article-title":"Physiotherapy for pain and disability in adults with complex regional pain syndrome (CRPS) types I and II","volume":"2","author":"Smart","year":"2016","journal-title":"Cochrane Database Syst Rev."},{"key":"bib7-20240731","article-title":"Characteristics and treatment outcomes in chromhidrosis: a systematic review","author":"Kashetsky","year":"2020","journal-title":"J Am Acad Dermatol."},{"issue":"11","key":"bib8-20240731","first-page":"245","article-title":"Treatment of complex regional pain syndrome in children and adolescents: a structured literature scoping review","volume":"7","author":"Vescio","year":"2020","journal-title":"Children (Basel)."},{"issue":"2","key":"bib9-20240731","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1097\/AJP.0000000000000530","article-title":"The experience of pain dismissal in adolescence","volume":"34","author":"Defenderfer","year":"2018","journal-title":"Clin J Pain."}],"container-title":["JBJS Case Connector"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.2106\/JBJS.CC.21.00194","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T13:43:48Z","timestamp":1787751828000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.2106\/JBJS.CC.21.00194"}},"subtitle":["A Case Report"],"short-title":[],"issued":{"date-parts":[[2021,7]]},"references-count":9,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.2106\/jbjs.cc.21.00194","relation":{},"ISSN":["2160-3251"],"issn-type":[{"value":"2160-3251","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,7]]}}}