{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T14:39:35Z","timestamp":1787755175949,"version":"build-2784847793"},"reference-count":17,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec>\n                    <jats:title>Case:<\/jats:title>\n                    <jats:p>A 66-year-old woman with polymyositis and recurrent urinary tract infections presented with lumbar pain and progressive lower extremity neuropathy. Imaging showed lytic destruction of the vertebral bone from L2 to L4 with extension into adjacent musculature. Histological examination demonstrated Michaelis-Gutmann bodies consistent with malakoplakia. The patient underwent revision T12-sacrum posterior fusion, L2-5 laminectomy, and anterior L3-4 corpectomy, followed by L2-4 anterior stabilization and a 6-week course of ceftriaxone. At 3 months postoperatively, she was asymptomatic without recurrence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Malakoplakia of bone should be considered in the differential diagnosis of lytic bone lesions and can be effectively treated with surgical debulking with penetrative antibiotics.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2106\/jbjs.cc.21.00328","type":"journal-article","created":{"date-parts":[[2021,9,3]],"date-time":"2021-09-03T10:03:54Z","timestamp":1630663434000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Surgically Managed Malakoplakia of the Spine"],"prefix":"10.2106","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3651-2361","authenticated-orcid":false,"given":"Amy L.","family":"Xu","sequence":"first","affiliation":[{"name":"From the Department of Orthopaedics, The Johns Hopkins Hospital, Baltimore, Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2477-8901","authenticated-orcid":false,"given":"Olivia","family":"Petrusky","sequence":"additional","affiliation":[{"name":"From the Department of Orthopaedics, The Johns Hopkins Hospital, Baltimore, Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0803-788X","authenticated-orcid":false,"given":"Jacob","family":"Babu","sequence":"additional","affiliation":[{"name":"From the Department of Orthopaedics, The Johns Hopkins Hospital, Baltimore, Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin Y.","family":"Wang","sequence":"additional","affiliation":[{"name":"From the Department of Orthopaedics, The Johns Hopkins Hospital, Baltimore, Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1743-7693","authenticated-orcid":false,"given":"Wesley M.","family":"Durand","sequence":"additional","affiliation":[{"name":"From the Department of Orthopaedics, The Johns Hopkins Hospital, Baltimore, Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4444-0297","authenticated-orcid":false,"given":"John M.","family":"Gross","sequence":"additional","affiliation":[{"name":"From the Department of Orthopaedics, The Johns Hopkins Hospital, Baltimore, Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian J.","family":"Neuman","sequence":"additional","affiliation":[{"name":"From the Department of Orthopaedics, The Johns Hopkins Hospital, Baltimore, Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2021,7]]},"reference":[{"issue":"pt 2","key":"bib1-20240805","first-page":"103","article-title":"Malakoplakia","volume":"16","author":"Damjanov","year":"1981","journal-title":"Pathol Annu."},{"issue":"2","key":"bib2-20240805","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/S0022-5347(17)54940-X","article-title":"Malacoplakia: a study of the literature and current concepts of pathogenesis, diagnosis and treatment","volume":"125","author":"Stanton","year":"1981","journal-title":"J Urol."},{"issue":"6","key":"bib3-20240805","doi-asserted-by":"crossref","first-page":"1703","DOI":"10.2214\/ajr.183.6.01831703","article-title":"Malacoplakia presenting as a solitary renal mass","volume":"183","author":"Wielenberg","year":"2004","journal-title":"AJR Am J Roentgenol."},{"issue":"2","key":"bib4-20240805","doi-asserted-by":"crossref","first-page":"297","DOI":"10.5858\/2007-131-297-MOTUT","article-title":"Malakoplakia outside the urinary tract","volume":"131","author":"Yousef","year":"2007","journal-title":"Arch Pathol Lab Med."},{"issue":"2","key":"bib5-20240805","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1302\/0301-620X.63B2.7217151","article-title":"Malacoplakia of bone: a case report","volume":"63-B","author":"Van den Bout","year":"1981","journal-title":"J Bone Joint Surg Br."},{"issue":"4","key":"bib6-20240805","doi-asserted-by":"crossref","first-page":"e116","DOI":"10.2106\/JBJS.CC.N.00103","article-title":"Malakoplakia of bone: a case report and review of the literature","volume":"4","author":"Lane","year":"2014","journal-title":"JBJS Case Connect."},{"issue":"3","key":"bib7-20240805","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1159\/000327638","article-title":"Malakoplakia of bone. 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