{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T03:36:45Z","timestamp":1787888205394,"version":"build-2784847793"},"reference-count":9,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"\n Case:<\/jats:title>\n A 52-year-old woman presented with localized hypersensitivity symptoms immediately after insertion of a carbon fiber-polyetheretherketone (CF-PEEK) vertebral fusion device. After a modified cutaneous patch test confirmed an allergic reaction to the implant, the device was surgically removed. The patient's symptoms were largely resolved 1 month after the removal of the device.<\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n CF-PEEK is a commonly used biomaterial in surgical implants. As far as we know, this is the first reported case of a hypersensitivity reaction to CF-PEEK.<\/jats:p>\n <\/jats:sec>","DOI":"10.2106\/jbjs.cc.21.00731","type":"journal-article","created":{"date-parts":[[2022,6,15]],"date-time":"2022-06-15T06:01:21Z","timestamp":1655272881000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Hypersensitivity Reaction to Carbon Fiber-Polyetheretherketone Composite Spinal Implant"],"prefix":"10.2106","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1952-6638","authenticated-orcid":false,"given":"Brian T.","family":"Bueno","sequence":"first","affiliation":[{"name":"Department of Orthopedics, Icahn School of Medicine at Mount Sinai, New York, New York"},{"name":"Department of Orthopaedics, Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7275-0607","authenticated-orcid":false,"given":"Mark","family":"Henry","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, Icahn School of Medicine at Mount Sinai, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7511-2486","authenticated-orcid":false,"given":"Samuel K.","family":"Cho","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, Icahn School of Medicine at Mount Sinai, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2022,4]]},"reference":[{"issue":"5","key":"bib1-20240805","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1007\/s00256-020-03622-6","article-title":"Multimodal imaging of composite carbon fiber-based implants for orthopedic spinal 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implants","volume":"28","author":"Kurtz","year":"2007","journal-title":"Biomaterials."},{"key":"bib5-20240805","doi-asserted-by":"crossref","first-page":"33","DOI":"10.4137\/CMAMD.S20354","article-title":"The use of carbon-fiber-reinforced (CFR) PEEK material in orthopedic implants: a systematic review","volume":"8","author":"Li","year":"2015","journal-title":"Clin Med Insights Arthritis Musculoskelet Disord."},{"key":"bib6-20240805","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1016\/j.wneu.2020.04.093","article-title":"Metal hypersensitivity after spinal instrumentation: when to suspect and how to treat","volume":"139","author":"Curley","year":"2020","journal-title":"World Neurosurg."},{"issue":"3","key":"bib7-20240805","doi-asserted-by":"crossref","first-page":"e241","DOI":"10.1097\/SCS.0000000000005192","article-title":"Allergic epidural effusion following polyetheretherketone cranioplasty","volume":"30","author":"Qiu","year":"2019","journal-title":"J Craniofac Surg."},{"issue":"1","key":"bib8-20240805","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1177\/1203475416665606","article-title":"Allergic reaction to polyether ether ketone following cross-reactivity to epoxy resin","volume":"21","author":"Kofler","year":"2017","journal-title":"J Cutan Med Surg."},{"issue":"1","key":"bib9-20240805","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1111\/os.12413","article-title":"Integral fixation titanium\/polyetheretherketone cages for cervical arthrodesis: evolution of cage design and early radiological outcomes and fusion rates","volume":"11","author":"Phan","year":"2019","journal-title":"Orthop Surg."}],"container-title":["JBJS Case 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