{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T14:46:19Z","timestamp":1787755579781,"version":"build-2784847793"},"reference-count":20,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec>\n                    <jats:title>Case:<\/jats:title>\n                    <jats:p>\n                      A 16-year-old boy with a history of Down syndrome presented with right knee pain and swelling. He was diagnosed with isolated septic arthritis of the knee due to\n                      <jats:italic toggle=\"yes\">Fusobacterium necrophorum<\/jats:italic>\n                      in the absence of current or recent oropharyngeal infection. He was successfully treated with arthroscopic irrigation and debridement and 12 weeks of oral antibiotics.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>\n                      <jats:italic toggle=\"yes\">Fusobacterium necrophorum<\/jats:italic>\n                      is a part of the normal oral flora and a rare cause of septic arthritis, typically associated with recent oropharyngeal infection. However, patients with immune dysregulation such as those with Down syndrome may develop isolated septic arthritis due to transient hematogenous seeding.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.2106\/jbjs.cc.22.00297","type":"journal-article","created":{"date-parts":[[2022,8,17]],"date-time":"2022-08-17T14:00:30Z","timestamp":1660744830000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Pediatric Septic Arthritis of the Knee due to Fusobacterium necrophorum in a Patient with Down Syndrome"],"prefix":"10.2106","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2226-4192","authenticated-orcid":false,"given":"Zoe","family":"Trutner","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery, University of California, Los Angeles, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4487-2818","authenticated-orcid":false,"given":"Richard","family":"Hwang","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, University of California, Los Angeles, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6563-3891","authenticated-orcid":false,"given":"Richard","family":"Bowen","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, University of California, Los Angeles, California"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2022,7]]},"reference":[{"issue":"2","key":"bib1-20240805","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.ocl.2016.12.008","article-title":"Pediatric septic arthritis","volume":"48","author":"Montgomery","year":"2017","journal-title":"Orthop Clin North 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