{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T14:41:34Z","timestamp":1787755294377,"version":"build-2784847793"},"reference-count":20,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec>\n                    <jats:title>Case:<\/jats:title>\n                    <jats:p>A 66-year-old man presented with new left hip pain after total hip arthroplasty 21 years earlier. Computed tomography imaging revealed massive osteolysis involving the ileum behind the well-fixed acetabular component. The patient was indicated for head and liner exchange with grafting of the osteolytic lesion. Surgery was complicated by cardiopulmonary arrest after injection of a bone graft substitute into the lesion. Despite resuscitation attempts, the patient died.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Embolism is a rare complication of bone graft substitute injection for pelvic osteolysis. This material can extravasate from bone and deposit in the pulmonary and cerebral microcirculation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2106\/jbjs.cc.22.00338","type":"journal-article","created":{"date-parts":[[2022,9,22]],"date-time":"2022-09-22T14:29:49Z","timestamp":1663856989000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Embolism After Injection of a Calcium Sulfate Bone Graft Substitute"],"prefix":"10.2106","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2522-8744","authenticated-orcid":false,"given":"Jacob M.","family":"Tadje","sequence":"first","affiliation":[{"name":"University of Washington School of Medicine, Seattle, Washington"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7690-918X","authenticated-orcid":false,"given":"S. Bradley","family":"Daines","sequence":"additional","affiliation":[{"name":"The Idaho Clinic, Boise, Idaho"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2022,7]]},"reference":[{"key":"bib2-20240805","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1302\/0301-620X.86B1.14040","article-title":"Biodegradation and biocompatibility of a calcium sulphate-hydroxyapatite bone substitute","volume":"86","author":"Nilsson","year":"2004","journal-title":"J Bone Joint Surg [Br]."},{"key":"bib3-20240805","first-page":"189PMC7785199","article-title":"Vascular extravasation of injectable bioresorbable bone cement during aspiration and injection of calcaneal bone cyst","volume":"34","author":"Wood","year":"2020","journal-title":"Proc (Bayl Univ Med Cent)."},{"key":"bib4-20240805","first-page":"7","article-title":"Lethality of embolized Norian bone cement varies with the time between mixing and embolization","author":"Bernards","year":"2004","journal-title":"50th Annu Meet Orthopaedic Res Soc."},{"issue":"2","key":"bib5-20240805","first-page":"235","article-title":"Unusual finding after contrast injection of a solitary bone cyst. 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