{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T14:44:45Z","timestamp":1787755485132,"version":"build-2784847793"},"reference-count":39,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec>\n                    <jats:title>Case:<\/jats:title>\n                    <jats:p>An 18-year-old immunocompetent man presented with symptomatic lumbar canal stenosis, discharging sinuses, and cold abscess for 3 years treated with multiple incision drainage procedures with cottonoid packing antibiotic therapy. Radiographic imaging showed a soft tissue mass in the canal causing bony destruction. Postoperative histopathological examination showed an Aspergillus fungal ball. Patient showed improvement at 6-month follow-up with medical management.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>As far as we know, this is the first case report showing an aspergilloma involving the vertebral column. Inadequate antibiotic treatment and blind introduction of a foreign body into sinus tracts can lead to fungal infections mimicking tuberculosis, causing disastrous outcomes. Fungal cultures are recommended routinely.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2106\/jbjs.cc.24.00190","type":"journal-article","created":{"date-parts":[[2024,8,29]],"date-time":"2024-08-29T19:09:08Z","timestamp":1724958548000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Aspergilloma Superinfection in the Spinal Canal of an 18-Year-Old Man"],"prefix":"10.2106","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-8010-8657","authenticated-orcid":false,"given":"Yash Prakash","family":"Ved","sequence":"first","affiliation":[{"name":"Department of Orthopaedics, Lokmanya Tilak Municipal Medical College and General Hospital, Mumbai, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-1196-9376","authenticated-orcid":false,"given":"Deepika","family":"Jain","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Seth G. S. Medical College and K. E. M. Hospital, Mumbai, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1031-9245","authenticated-orcid":false,"given":"Tushar","family":"Rathod","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Seth G. S. Medical College and K. E. M. Hospital, Mumbai, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,7]]},"reference":[{"issue":"3","key":"bib2-20240829","doi-asserted-by":"crossref","first-page":"1801184","DOI":"10.1183\/13993003.01184-2018","article-title":"Chronic pulmonary aspergillosis commonly complicates treated pulmonary tuberculosis with residual cavitation","volume":"53","author":"Page","year":"2019","journal-title":"Eur Respir J."},{"issue":"8","key":"bib3-20240829","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1136\/thoraxjnl-2020-216464","article-title":"A prospective longitudinal study of chronic pulmonary aspergillosis in pulmonary tuberculosis in Indonesia (APICAL)","volume":"77","author":"Setianingrum","year":"2022","journal-title":"Thorax."},{"issue":"2","key":"bib4-20240829","doi-asserted-by":"crossref","first-page":"91","DOI":"10.5005\/jp-journals-10079-1051","article-title":"Thoracic fungal osteomyelitis with compressive myelopathy in an immunocompetent individual by a rare Fusarium species: a case report","volume":"3","author":"Raju","year":"2021","journal-title":"J Orthopedics Joint Surg."},{"key":"bib5-20240829","first-page":"8705204","article-title":"A rare case of pheohyphomycotic lumbar spondylodiscitis mistreated as Koch's spine","volume":"2016","author":"Goel","year":"2016","journal-title":"Case Rep Orthopedics."},{"issue":"5","key":"bib6-20240829","doi-asserted-by":"crossref","first-page":"W919","DOI":"10.2214\/AJR.11.6786","article-title":"MRI findings of Aspergillus spondylitis","volume":"197","author":"Jong","year":"2011","journal-title":"AJR Am J Roentgenol."},{"issue":"2","key":"bib7-20240829","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1007\/s00264-011-1461-x","article-title":"Microbiological diagnosis of spinal tuberculosis","volume":"36","author":"Merino","year":"2012","journal-title":"Int Orthopaedics."},{"issue":"296","key":"bib8-20240829","first-page":"192","article-title":"Comparison of tuberculous and pyogenic spondylitis. An analysis of 122 cases","volume":"296","author":"Buchelt","year":"1993","journal-title":"Clin Orthopaedics Relat Res."},{"issue":"1","key":"bib9-20240829","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1186\/s12879-016-1897-0","article-title":"Comparison of characteristics of culture-negative pyogenic spondylitis and tuberculous spondylitis: a retrospective study","volume":"16","author":"Kim","year":"2016","journal-title":"BMC Infect Dis."},{"issue":"6","key":"bib10-20240829","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1046\/j.1365-2303.1999.00206.x","article-title":"Value of radiologically guided fine needle aspiration cytology (FNAC) in the diagnosis of spinal tuberculosis: a study of 29 cases","volume":"10","author":"Francis","year":"1999","journal-title":"Cytopathology."},{"issue":"20","key":"bib11-20240829","doi-asserted-by":"crossref","first-page":"1140","DOI":"10.21037\/atm-22-4661","article-title":"Image-guided percutaneous biopsy and pathological diagnosis in atypical tuberculous spondylitis: a case series and clinical outcomes","volume":"10","author":"Lu","year":"2022","journal-title":"Ann Translational Med."},{"key":"bib12-20240829","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.ijid.2022.05.021","article-title":"Positivity rates of mycobacterial culture in patients with tuberculous spondylitis according to methods and sites of biopsies: an analysis of 206 cases","volume":"121","author":"Lee","year":"2022","journal-title":"Int J Infect Dis."},{"issue":"6","key":"bib13-20240829","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1007\/s10096-004-1148-y","article-title":"Tuberculous vertebral osteomyelitis in the new millennium: still a diagnostic and therapeutic challenge","volume":"23","author":"Colmenero","year":"2004","journal-title":"Eur J Clin Microbiol Infect Dis."},{"issue":"9","key":"bib14-20240829","first-page":"855","article-title":"Yield of smear, culture and amplification tests from repeated sputum induction for the diagnosis of pulmonary tuberculosis","volume":"5","author":"Al Zahrani","year":"2001","journal-title":"Int J Tuberculosis Lung Dis."},{"issue":"5","key":"bib15-20240829","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1016\/j.jinf.2013.12.008","article-title":"Aspergillus osteomyelitis: epidemiology, clinical manifestations, management, and outcome","volume":"68","author":"Gamaletsou","year":"2014","journal-title":"J Infect."},{"issue":"6","key":"bib16-20240829","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1111\/myc.12165","article-title":"Aspergillosis of bones and joints - a review from 2002 until today","volume":"57","author":"Koehler","year":"2014","journal-title":"Mycoses."},{"issue":"1","key":"bib17-20240829","doi-asserted-by":"crossref","first-page":"23","DOI":"10.14245\/ns.2040338.169","article-title":"Spontaneous vertebral aspergillosis, the state of art: a systematic literature review","volume":"18","author":"Perna","year":"2021","journal-title":"Neurospine."},{"issue":"6","key":"bib18-20240829","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1111\/1469-0691.12389","article-title":"Osteomyelitis caused by Aspergillus species: a review of 310 reported cases","volume":"20","author":"Gabrielli","year":"2014","journal-title":"Clin Microbiol Infect."},{"issue":"4","key":"bib21-20240829","doi-asserted-by":"crossref","first-page":"422","DOI":"10.5152\/balkanmedj.2013.8732","article-title":"Spinal textiloma (gossypiboma): a report of three cases misdiagnosed as tumour","volume":"30","author":"\u015eahin","year":"2013","journal-title":"Balkan Med J."},{"key":"bib22-20240829","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/j.wneu.2018.05.119","article-title":"Retention of nonabsorbable hemostatic materials (retained surgical sponge, gossypiboma, textiloma, gauzoma, muslinoma) after spinal surgery: a systematic review of cases reported during the last half-century","volume":"116","author":"Turgut","year":"2018","journal-title":"World Neurosurg."},{"issue":"1","key":"bib23-20240829","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1186\/s12891-020-03582-x","article-title":"Aspergillus spondylitis: case series and literature review","volume":"21","author":"Dai","year":"2020","journal-title":"BMC Musculoskelet Disord."},{"issue":"4","key":"bib24-20240829","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1093\/cid\/ciw444","article-title":"Executive summary: practice guidelines for the diagnosis and management of aspergillosis: 2016 update by the infectious diseases society of America","volume":"63","author":"Patterson","year":"2016","journal-title":"Clin Infect Dis."},{"issue":"8","key":"bib25-20240829","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/j.eimc.2018.03.018","article-title":"Executive summary of clinical practice guideline for the management of invasive diseases caused by Aspergillus: 2018 Update by the GEMICOMED-SEIMC\/REIPI","volume":"37","author":"Garcia-Vidal","year":"2018","journal-title":"Enferm Infecc Microbiol Clinica (Engl Ed)."},{"issue":"3","key":"bib26-20240829","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1016\/j.spinee.2018.08.001","article-title":"Fungal spinal epidural abscess: a case series of nine patients","volume":"19","author":"Yang","year":"2019","journal-title":"Spine J."},{"issue":"6","key":"bib27-20240829","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1056\/NEJMoa020191","article-title":"Voriconazole versus amphotericin B for primary therapy of invasive aspergillosis","volume":"347","author":"Herbrecht","year":"2002","journal-title":"New Engl J Med."},{"issue":"5","key":"bib28-20240829","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1093\/cid\/ciu911","article-title":"Application of the 2008 definitions for invasive fungal diseases to the trial comparing voriconazole versus amphotericin B for therapy of invasive aspergillosis: a collaborative study of the mycoses study group (MSG 05) and the European organization for research and treatment of cancer infectious diseases group","volume":"60","author":"Herbrecht","year":"2015","journal-title":"Clin Infect Dis."},{"issue":"10","key":"bib29-20240829","doi-asserted-by":"crossref","first-page":"1899","DOI":"10.3390\/diagnostics11101899","article-title":"Spondylodiscitis caused by Aspergillus species","volume":"11","author":"Koutserimpas","year":"2021","journal-title":"Diagnostics."},{"issue":"6","key":"bib30-20240829","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.2214\/ajr.182.6.1821405","article-title":"Discrimination of tuberculous spondylitis from pyogenic spondylitis on MRI","volume":"182","author":"Jung","year":"2004","journal-title":"AJR Am J Roentgenol."},{"issue":"1070","key":"bib31-20240829","doi-asserted-by":"crossref","first-page":"20160761","DOI":"10.1259\/bjr.20160761","article-title":"Gossypibomas, a surgeon's nightmare\u2014patient demographics, risk factors, imaging and how we can prevent it","volume":"90","author":"Mathew","year":"2017","journal-title":"Br J Radiol."},{"issue":"4","key":"bib32-20240829","first-page":"709","article-title":"MR imaging findings of paravertebral gossypiboma","volume":"28","author":"Kim","year":"2007","journal-title":"AJNR Am J Neuroradiol."},{"issue":"3","key":"bib33-20240829","first-page":"98","article-title":"MR findings of surgically retained sponges and towels: report of two cases","volume":"11","author":"Kuwashima","year":"1993","journal-title":"Radiat Med."},{"issue":"6","key":"bib34-20240829","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1097\/00004728-199611000-00009","article-title":"CT of retained surgical sponges (Textilomas): pitfalls in detection and evaluation","volume":"20","author":"Kopka","year":"1996","journal-title":"J Comput Assist Tomography."},{"issue":"31","key":"bib35-20240829","doi-asserted-by":"crossref","first-page":"4927","DOI":"10.3748\/wjg.v11.i31.4927","article-title":"Calcified reticulate rind sign: a characteristic feature of gossypiboma on computed tomography","volume":"11","author":"Lu","year":"2005","journal-title":"World J Gastroenterol."},{"issue":"3","key":"bib36-20240829","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1097\/WCO.0b013e3282fee95b","article-title":"Fungal brain infections","volume":"21","author":"Scully","year":"2008","journal-title":"Curr Opin Neurol."},{"key":"bib37-20240829","first-page":"211","article-title":"Brain aspergilloma in an immunocompetent individual: a case report","volume":"11","author":"Ribeiro Mem\u00f3ria","year":"2020","journal-title":"Surg Neurol Int."},{"issue":"2","key":"bib38-20240829","doi-asserted-by":"crossref","first-page":"89","DOI":"10.2176\/nmc.47.89","article-title":"Local administration of amphotericin B against aspergilloma in the prepontine cistern--case report","volume":"47","author":"Nabika","year":"2007","journal-title":"Neurol Med Chir (Tokyo)."},{"issue":"2","key":"bib39-20240829","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1080\/10790268.2010.11689691","article-title":"Imaging diagnosis of spinal intramedullary tuberculoma: case reports and literature review","volume":"33","author":"Lu","year":"2010","journal-title":"J Spinal Cord Med."},{"issue":"10","key":"bib40-20240829","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1055\/s-0043-120766","article-title":"CT and MRI findings in cerebral aspergilloma","volume":"190","author":"G\u00e4rtner","year":"2018","journal-title":"RoFo."},{"issue":"12","key":"bib41-20240829","first-page":"e20133","article-title":"Diagnostic and neurological overview of brain tuberculomas: a review of literature","volume":"13","author":"Perez-Malagon","year":"2021","journal-title":"Cureus."},{"issue":"3","key":"bib42-20240829","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/j.ijid.2005.04.008","article-title":"Isolated spinal intramedullary tuberculoma in a healthy immunocompetent adult","volume":"10","author":"Deogaonkar","year":"2006","journal-title":"Int J Infect Dis IJID."}],"container-title":["JBJS Case Connector"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.2106\/JBJS.CC.24.00190","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T13:43:56Z","timestamp":1787751836000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.2106\/JBJS.CC.24.00190"}},"subtitle":["A Case Report"],"short-title":[],"issued":{"date-parts":[[2024,7]]},"references-count":39,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.2106\/jbjs.cc.24.00190","relation":{},"ISSN":["2160-3251"],"issn-type":[{"value":"2160-3251","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7]]}}}