{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T14:46:44Z","timestamp":1787755604944,"version":"build-2784847793"},"reference-count":27,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec>\n                    <jats:title>Case:<\/jats:title>\n                    <jats:p>A 68-year-old woman presented with pain in her left hip and a discharging sinus for 8 months. Ten months previously, she had undergone a revision total hip arthroplasty (THA) for aseptic loosening of a THA initially performed 30 years ago. This time, she underwent a 2-stage re-revision. Targeted next-generation sequencing identified the organism as Mycobacterium Tuberculosis, followed by antitubercular therapy for 9 months. After a 5-year follow-up, Harris Hip Score was 85%, and there was no evidence of infection or prosthetic loosening.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>High index of suspicion and genomic sequencing may be required to identify the organism in tubercular periprosthetic infections.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2106\/jbjs.cc.25.00175","type":"journal-article","created":{"date-parts":[[2025,6,5]],"date-time":"2025-06-05T14:10:31Z","timestamp":1749132631000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Two-Stage Re-revision for Tuberculosis Affecting a Revision Total Hip Arthroplasty"],"prefix":"10.2106","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5088-2561","authenticated-orcid":false,"given":"Narayan","family":"Hulse","sequence":"first","affiliation":[{"name":"Department of Bone and Joints, Fortis Hospital, Bangalore, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,4]]},"reference":[{"issue":"11","key":"bib1-20250605","doi-asserted-by":"crossref","first-page":"1464","DOI":"10.1302\/0301-620X.96B11.33949","article-title":"Early morbidity after aseptic revision hip arthroplasty in Denmark: a two-year nationwide study","volume":"96-B","author":"Lindberg-Larsen","year":"2014","journal-title":"Bone Joint J."},{"issue":"9","key":"bib2-20250605","first-page":"B5397","article-title":"Prosthetic joint infection following total hip arthroplasty - incidence, mortality and validation of the diagnosis in the Danish hip arthroplasty register","volume":"64","author":"Gundtoft","year":"2017","journal-title":"Dan Med J."},{"issue":"2","key":"bib3-20250605","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1302\/0301-620X.88B2.17058","article-title":"The management of peri-prosthetic infection in total joint arthroplasty","volume":"88","author":"Toms","year":"2006","journal-title":"J Bone Joint Surg Br."},{"issue":"1","key":"bib4-20250605","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1186\/s12891-024-08053-1","article-title":"Total hip arthroplasty in hip tuberculosis: a systematic review","volume":"26","author":"Zheng","year":"2025","journal-title":"BMC Musculoskelet Disord."},{"issue":"8","key":"bib5-20250605","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1007\/s00264-009-0854-6","article-title":"Total hip arthroplasty for active tuberculosis of the hip","volume":"34","author":"Wang","year":"2010","journal-title":"Int Orthop."},{"issue":"3-4","key":"bib6-20250605","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1007\/s004230050130","article-title":"Haematogenous tuberculous infection following revision of a loosened total hip replacement","volume":"383","author":"Bruns","year":"1998","journal-title":"Langenbecks Arch Surg."},{"key":"bib7-20250605","doi-asserted-by":"crossref","first-page":"107601","DOI":"10.1016\/j.rmed.2024.107601","article-title":"Diagnosis of extra pulmonary tuberculosis: an update on novel diagnostic approaches","volume":"225","author":"Jain","year":"2024","journal-title":"Respir Med."},{"issue":"4","key":"bib8-20250605","doi-asserted-by":"crossref","first-page":"1202","DOI":"10.1128\/JCM.02268-10","article-title":"Rapid molecular detection of extrapulmonary tuberculosis by the automated genexpert MTB\/RIF system","volume":"49","author":"Hillemann","year":"2011","journal-title":"J Clin Microbiol."},{"issue":"5","key":"bib9-20250605","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1016\/j.arth.2018.02.078","article-title":"The 2018 definition of periprosthetic hip and knee infection: an evidence-based and validated criteria","volume":"33","author":"Parvizi","year":"2018","journal-title":"J Arthroplasty."},{"issue":"7","key":"bib10-20250605","doi-asserted-by":"crossref","first-page":"e147","DOI":"10.1093\/cid\/ciw376","article-title":"Official American thoracic society\/centers for disease control and prevention\/infectious diseases society of America clinical practice guidelines: treatment of drug-susceptible tuberculosis","volume":"63","author":"Nahid","year":"2016","journal-title":"Clin Infect Dis."},{"key":"bib11-20250605","first-page":"119","article-title":"Hip replacement: treatment of femoral bone loss using distal bypass fixation","volume":"49","author":"Paprosky","year":"2000","journal-title":"Instr Course Lect."},{"issue":"1","key":"bib12-20250605","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/0883-5403(94)90135-X","article-title":"Acetabular defect classification and surgical reconstruction in revision arthroplasty. 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