{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T14:50:23Z","timestamp":1787755823589,"version":"build-2784847793"},"reference-count":12,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec>\n                    <jats:title>Case:<\/jats:title>\n                    <jats:p>Drug-induced fever is a rare adverse reaction to antibiotics. This case report describes 2 cases of suspected rifampicin-induced fever in patients undergoing periprosthetic joint infection treatment. Both patients experienced fever with the absence of inflammatory symptoms and a discrepancy between clinical improvement and persistent fever. Discontinuation of rifampicin led to rapid symptom resolution.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Drug-induced fever should be considered when fever persists without infectious symptoms and after excluding other causes. Prompt recognition and discontinuation can lead to rapid resolution and minimize unnecessary interventions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2106\/jbjs.cc.25.00230","type":"journal-article","created":{"date-parts":[[2025,12,5]],"date-time":"2025-12-05T19:00:28Z","timestamp":1764961228000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Suspected Rifampicin-Induced Fever During Periprosthetic Joint Infection Treatment"],"prefix":"10.2106","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-5948-704X","authenticated-orcid":false,"given":"Sophie A.","family":"Zwarts","sequence":"first","affiliation":[{"name":"Department of Orthopedic Surgery, Frisius Medical Centre, Leeuwarden, the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8455-9690","authenticated-orcid":false,"given":"Kyrill","family":"Rykov","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, Isala Hospital, Zwolle, the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-2144-3497","authenticated-orcid":false,"given":"Pelle","family":"Bos","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, Frisius Medical Centre, Leeuwarden, the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1644-4015","authenticated-orcid":false,"given":"Joris J.W.","family":"Ploegmakers","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, University Medical Center Groningen, Groningen, the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6410-3824","authenticated-orcid":false,"given":"Wierd P.","family":"Zijlstra","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, Frisius Medical Centre, Leeuwarden, the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7866-2467","authenticated-orcid":false,"given":"Marjan","family":"Wouthuyzen-Bakker","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology and Infection Prevention, University Medical Center Groningen, Groningen, the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,10]]},"reference":[{"issue":"4","key":"bib1-20251205","doi-asserted-by":"crossref","first-page":"95","DOI":"10.37737\/ace.23013","article-title":"Drug fever: a narrative 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Cases"],"short-title":[],"issued":{"date-parts":[[2025,10]]},"references-count":12,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.2106\/jbjs.cc.25.00230","relation":{},"ISSN":["2160-3251"],"issn-type":[{"value":"2160-3251","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10]]}}}