{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T14:51:47Z","timestamp":1787755907812,"version":"build-2784847793"},"reference-count":17,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec>\n                    <jats:title>Case:<\/jats:title>\n                    <jats:p>Familial expansile osteolysis (FEO) is a rare inherited autosomal dominant condition causing the development of painful lytic bone lesions. We present the case of a 54-year-old man with FEO who was treated with denosumab. The patient's progress was monitored with radiographs, magnetic resonance imaging, bone turnover markers, pain, and functional scores.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The use of denosumab for FEO displays improvement in radiological appearances of the affected bone, increased quality of life and may prevent the development of further lesions. It is a safe treatment modality for patients with FEO that allows for limb salvage surgery rather than amputation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2106\/jbjs.cc.25.00353","type":"journal-article","created":{"date-parts":[[2025,11,20]],"date-time":"2025-11-20T19:00:30Z","timestamp":1763665230000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["A Novel Approach to the Treatment of Familial Expansile Osteolysis: A Rare Genetic Bone Pathology"],"prefix":"10.2106","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1163-8598","authenticated-orcid":false,"given":"Stephanie","family":"Lennon","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery, Flinders Medical Centre, Bedford Park, South Australia, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phil","family":"Allen","sequence":"additional","affiliation":[{"name":"Department of 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