{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T20:05:02Z","timestamp":1792872302773,"version":"4.5.0"},"reference-count":25,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec>\n                    <jats:title>Case:<\/jats:title>\n                    <jats:p>\n                      A 74-year-old woman developed refractory\n                      <jats:italic toggle=\"yes\">Candida parapsilosis<\/jats:italic>\n                      periprosthetic joint infection (PJI) after total knee arthroplasty. Despite repeated debridement, implant removal, antifungal-loaded cement spacers, and prolonged systemic antifungal therapy, infection recurred and amputation was considered. Daily intra-articular low-dose povidone-iodine instillation achieved infection control without adverse events. After a 1-month drug holiday, hinged revision arthroplasty was performed. At 2 years, she ambulated independently without recurrence.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Repeated low-dose povidone-iodine instillation may be a salvage option for refractory fungal PJI.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2106\/jbjs.cc.26.00121","type":"journal-article","created":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T18:01:34Z","timestamp":1783620094000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Daily Low-Dose Intra-Articular Povidone-Iodine Salvage of Refractory Fungal Total Knee Arthroplasty Infection"],"prefix":"10.2106","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-2094-4804","authenticated-orcid":false,"given":"Yutaka","family":"Fujita","sequence":"first","affiliation":[{"name":"Department of 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