{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T18:21:36Z","timestamp":1787768496649,"version":"build-2784847793"},"reference-count":7,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec>\n                    <jats:title>Case:<\/jats:title>\n                    <jats:p>A 40-year-old woman with diabetes presented with a nonhealing, ischemic through-knee amputation stump. To avoid transfemoral amputation, we adapted the transverse bone transport technique for the femur, modifying the surgical procedure by using a tibial fixator. A dual-cycle cortical distraction protocol successfully induced local angiogenesis, transforming the avascular tissue into a granulating wound bed and allowing for primary closure and limb salvage.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Previously described only in the tibia, this first application of transverse bone transport provides compelling early evidence, 8 months postoperatively, that distraction-induced angiogenesis is a feasible and promising limb-salvage strategy for refractory amputation stumps at the femoral level.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2106\/jbjs.cc.26.00235","type":"journal-article","created":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T18:00:29Z","timestamp":1787767229000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Transverse Femoral Bone Transport for Refractory Diabetic Stump Ulceration"],"prefix":"10.2106","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7887-497X","authenticated-orcid":false,"given":"Alex","family":"Trompeter","sequence":"first","affiliation":[{"name":"Trauma and Orthopaedics Department, St. George's University Hospitals NHS Foundation Trust, London, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-2831-1553","authenticated-orcid":false,"given":"Fabio","family":"Casero","sequence":"additional","affiliation":[{"name":"Trauma and Orthopaedics Department, St. George's University Hospitals NHS Foundation Trust, London, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-0127-9529","authenticated-orcid":false,"given":"Katie","family":"Hutchinson","sequence":"additional","affiliation":[{"name":"Trauma and Orthopaedics Department, St. George's University Hospitals NHS Foundation Trust, London, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,7]]},"reference":[{"issue":"1","key":"bib1-20260826","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1001\/jama.2023.10578","article-title":"Diabetic foot ulcers: a review","volume":"330","author":"Armstrong","year":"2023","journal-title":"JAMA."},{"key":"bib2-20260826","first-page":"1095361","article-title":"Effectiveness of transverse tibial bone transport in treatment of diabetic foot ulcer: a systematic review and meta-analysis","volume":"13","author":"Zhang","year":"2022","journal-title":"Front Endocrinol (Lausanne)."},{"issue":"8","key":"bib3-20260826","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1177\/10711007251341312","article-title":"A systematic review on tibial cortex transverse transport in the treatment of ischemic ulcers of the lower limb","volume":"46","author":"Luxon","year":"2025","journal-title":"Foot Ankle Int."},{"key":"bib4-20260826","doi-asserted-by":"crossref","first-page":"100353","DOI":"10.1016\/j.jvsvi.2026.100353","article-title":"Real-world outcomes of above-knee amputation: investigating the impact of peripheral arterial disease","volume":"4","author":"Thomas","year":"2026","journal-title":"JVS-Vascular Insights."},{"key":"bib5-20260826","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1097\/00003086-198901000-00038","article-title":"The tension-stress effect on the genesis and growth of tissues: part I: the influence of stability of fixation and soft-tissue preservation","volume":"238","author":"Ilizarov","year":"1989","journal-title":"Clin Orthop Relat Res."},{"issue":"9","key":"bib6-20260826","doi-asserted-by":"crossref","first-page":"2170","DOI":"10.1111\/os.13416","article-title":"Transverse tibial bone transport enhances distraction osteogenesis and vascularization in the treatment of diabetic foot","volume":"14","author":"Ou","year":"2022","journal-title":"Orthop Surg."},{"issue":"suppl 2","key":"bib7-20260826","doi-asserted-by":"crossref","first-page":"hcae175.282","DOI":"10.1093\/qjmed\/hcae175.282","article-title":"Evaluation of vacuum-assisted dressing on treatment of ischemic above knee amputation stump and the rate of healing of the amputation stump","volume":"117","author":"Abdelmageed","year":"2024","journal-title":"QJM: An Int J Med."}],"container-title":["JBJS Case Connector"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.2106\/JBJS.CC.26.00235","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T18:00:30Z","timestamp":1787767230000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.2106\/JBJS.CC.26.00235"}},"subtitle":["A Case Report"],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":7,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.2106\/jbjs.cc.26.00235","relation":{},"ISSN":["2160-3251"],"issn-type":[{"value":"2160-3251","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7]]}}}