{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T14:28:05Z","timestamp":1787754485022,"version":"build-2784847793"},"reference-count":13,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JBJS Case Connector"],"published-print":{"date-parts":[[2015,3,25]]},"abstract":"<jats:sec>\n                    <jats:title>Case:<\/jats:title>\n                    <jats:p>Prior to the emergence of bone marrow transplantation as a treatment for Hurler syndrome, most individuals with this syndrome did not survive into their teenage years. We describe a twenty-three-year-old patient with Hurler syndrome who had been treated with bone marrow transplantation; we focus on the presentation and treatment of the associated carpal tunnel syndrome and trigger digits. After initial trigger digit release and revision bilateral carpal tunnel release with a tenosynovectomy, he maintained symptom-free hand function.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Surgical treatment of median nerve compression and trigger digits due to Hurler syndrome is effective in the long term.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2106\/jbjs.cc.n.00132","type":"journal-article","created":{"date-parts":[[2015,3,26]],"date-time":"2015-03-26T06:08:57Z","timestamp":1427350137000},"page":"e27","source":"Crossref","is-referenced-by-count":3,"title":["Long-Term Results of Carpal Tunnel and Trigger Finger Releases in a Patient with Hurler Syndrome"],"prefix":"10.2106","volume":"5","author":[{"given":"Mitchell","family":"Wyffels","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery, University of Minnesota, 2450 Riverside Avenue, Suite R200, Minneapolis, MN 55454. E-mail address for A.E. Van Heest:"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul J.","family":"Orchard","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University of Minnesota, 420 Delaware Street S.E., MMC 366, Minneapolis, MN 55455"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ann E.","family":"Van Heest","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, University of Minnesota, 2450 Riverside Avenue, Suite R200, Minneapolis, MN 55454. E-mail address for A.E. Van Heest:"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"issue":"5","key":"bib1-20230712","first-page":"802","article-title":"Chromosomal localization of the human alpha-L-iduronidase gene (IDUA) to 4p16.3","volume":"47","author":"Scott","year":"1990","journal-title":"Am J Hum Genet."},{"issue":"6","key":"bib2-20230712","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1007\/s10545-005-0112-z","article-title":"Cumulative incidence rates of the mucopolysaccharidoses in Germany","volume":"28","author":"Baehner","year":"2005","journal-title":"J Inherit Metab Dis."},{"issue":"5","key":"bib4-20230712","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1016\/j.bbmt.2008.01.009","article-title":"The clinical outcome of Hurler syndrome after stem cell transplantation","volume":"14","author":"Aldenhoven","year":"2008","journal-title":"Biol Blood Marrow Transplant."},{"issue":"5","key":"bib5-20230712","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1016\/j.bbmt.2009.01.020","article-title":"Risk factor analysis of outcomes after unrelated cord blood transplantation in patients with hurler syndrome","volume":"15","author":"Boelens","year":"2009","journal-title":"Biol Blood Marrow Transplant."},{"issue":"7","key":"bib6-20230712","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.1038\/bmt.2009.319","article-title":"Pre-transplant risk factors affecting outcome in Hurler syndrome","volume":"45","author":"Orchard","year":"2010","journal-title":"Bone Marrow Transplant."},{"issue":"1","key":"bib7-20230712","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1053\/j.seminhematol.2009.10.008","article-title":"Transplant outcomes in mucopolysaccharidoses","volume":"47","author":"Prasad","year":"2010","journal-title":"Semin Hematol."},{"issue":"19","key":"bib8-20230712","doi-asserted-by":"crossref","first-page":"3981","DOI":"10.1182\/blood-2012-09-455238","article-title":"Outcomes of transplantation using various hematopoietic cell sources in children with Hurler syndrome after myeloablative conditioning","volume":"121","author":"Boelens","year":"2013","journal-title":"Blood."},{"issue":"7","key":"bib9-20230712","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1016\/S0002-9149(03)00909-3","article-title":"Usefulness of bone marrow transplantation in the Hurler syndrome","volume":"92","author":"Braunlin","year":"2003","journal-title":"Am J Cardiol."},{"issue":"3","key":"bib10-20230712","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1007\/s10545-011-9304-x","article-title":"Orthopaedic management of Hurler\u2019s disease after hematopoietic stem cell transplantation: a systematic review","volume":"34","author":"van der Linden","year":"2011","journal-title":"J Inherit Metab Dis."},{"issue":"104","key":"bib11-20230712","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1097\/00003086-197410000-00020","article-title":"The hand in mucopolysaccharide disorders","author":"Fisher","year":"1974","journal-title":"Clin Orthop Relat Res."},{"issue":"2","key":"bib12-20230712","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/S0363-5023(98)80120-2","article-title":"Surgical treatment of carpal tunnel syndrome and trigger digits in children with mucopolysaccharide storage disorders","volume":"23","author":"Van Heest","year":"1998","journal-title":"J Hand Surg Am."},{"issue":"6","key":"bib13-20230712","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1038\/sj.bmt.1705586","article-title":"Analysis of factors affecting development of carpal tunnel syndrome in patients with Hurler syndrome after hematopoietic cell transplantation","volume":"39","author":"Khanna","year":"2007","journal-title":"Bone Marrow Transplant."},{"key":"bib14-20230712","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD009354.pub2","article-title":"Enzyme replacement therapy with laronidase (Aldurazyme) for treating mucopolysaccharidosis type I","volume":"11","author":"Jameson","year":"2013","journal-title":"Cochrane Database Syst Rev."}],"container-title":["JBJS Case Connector"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/01709767-201505010-00027","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T13:28:13Z","timestamp":1787750893000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/01709767-201505010-00027"}},"subtitle":["A Case Report"],"short-title":[],"issued":{"date-parts":[[2015,3,25]]},"references-count":13,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2015]]}},"URL":"https:\/\/doi.org\/10.2106\/jbjs.cc.n.00132","relation":{},"ISSN":["2160-3251"],"issn-type":[{"value":"2160-3251","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,3,25]]}}}